CompoundList
Sign in
Murcko scaffold

Pyrimidine scaffold

19,000 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
19,000
With full pages
2,066
Scaffold SMILES

c1cncnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Pyrimidine page
Murcko scaffold c1cncnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,825 to 1,872 of 19,000 chemicals

2-Chloro-pyrimidine-5-carboxylic acid ethyl ester chemical structure, C7H7ClN2O2, CAS 89793-12-4
2-Chloro-pyrimidine-5-carboxylic acid ethyl ester
CAS 89793-12-4C7H7ClN2O2
4-Chloro-5-(2-chloroethyl)-6-methylpyrimidin-2-amine chemical structure, C7H9Cl2N3, CAS 306314-90-9
4-Chloro-5-(2-chloroethyl)-6-methylpyrimidin-2-amine
CAS 306314-90-9C7H9Cl2N3
Ethyl 4-(Isopropylamino)-2-(methylthio)pyrimidine-5-carboxylate chemical structure, C11H17N3O2S, CAS 25693-79-2
Ethyl 4-(Isopropylamino)-2-(methylthio)pyrimidine-5-carboxylate
CAS 25693-79-2C11H17N3O2S
2,4-Bis-(trifluoromethyl)pyrimidine-5-carboxylic acid ethyl ester chemical structure, C9H6F6N2O2, CAS 188781-15-9
2,4-Bis-(trifluoromethyl)pyrimidine-5-carboxylic acid ethyl ester
CAS 188781-15-9C9H6F6N2O2
3-[(Pyrimidin-2-yl)amino]propanoic acid chemical structure, C7H9N3O2, CAS 339195-50-5
3-[(Pyrimidin-2-yl)amino]propanoic acid
CAS 339195-50-5C7H9N3O2
N'4'-sec-Butyl-6-chloro-pyrimidine-4,5-diamine chemical structure, C8H13ClN4, CAS 195252-58-5
N'4'-sec-Butyl-6-chloro-pyrimidine-4,5-diamine
CAS 195252-58-5C8H13ClN4
4-Methyl-2-(trifluoromethyl)pyrimidine-5-carboxylic acid chemical structure, C7H5F3N2O2, CAS 306960-74-7
4-Methyl-2-(trifluoromethyl)pyrimidine-5-carboxylic acid
CAS 306960-74-7C7H5F3N2O2
2-(Dimethylamino)-4-propylpyrimidine-5-carboxylic acid chemical structure, C10H15N3O2, CAS 180283-74-3
2-(Dimethylamino)-4-propylpyrimidine-5-carboxylic acid
CAS 180283-74-3C10H15N3O2
5-Iodo-2-methoxypyrimidine chemical structure, C5H5IN2O, CAS 101803-06-9
5-Iodo-2-methoxypyrimidine
CAS 101803-06-9C5H5IN2O
Ethyl 4-(ethylamino)-2-(methylthio)pyrimidine-5-carboxylate chemical structure, C10H15N3O2S, CAS 185040-33-9
Ethyl 4-(ethylamino)-2-(methylthio)pyrimidine-5-carboxylate
CAS 185040-33-9C10H15N3O2S
Methyl 2,6-dimethoxy-5-nitropyrimidine-4-carboxylate chemical structure, C8H9N3O6, CAS 226559-52-0
Methyl 2,6-dimethoxy-5-nitropyrimidine-4-carboxylate
CAS 226559-52-0C8H9N3O6
4-(Isobutylamino)-2-(methylthio)pyrimidine-5-carboxylic acid ethyl ester chemical structure, C12H19N3O2S, CAS 1027013-37-1
4-(Isobutylamino)-2-(methylthio)pyrimidine-5-carboxylic acid ethyl ester
CAS 1027013-37-1C12H19N3O2S
2-Chloro-6-methylpyrimidine-4-carboxylic acid chemical structure, C6H5ClN2O2, CAS 89581-58-8
2-Chloro-6-methylpyrimidine-4-carboxylic acid
CAS 89581-58-8C6H5ClN2O2
(4-(Isopropylamino)-2-(methylthio)pyrimidin-5-yl)methanol chemical structure, C9H15N3OS, CAS 321690-72-6
(4-(Isopropylamino)-2-(methylthio)pyrimidin-5-yl)methanol
CAS 321690-72-6C9H15N3OS
2,4-Bis(trifluoromethyl)pyrimidine-5-carboxylic acid chemical structure, C7H2F6N2O2, CAS 188781-46-6
2,4-Bis(trifluoromethyl)pyrimidine-5-carboxylic acid
CAS 188781-46-6C7H2F6N2O2
Heteromine G chemical structure, C9H15N5O2, CAS 196090-70-7
Heteromine G
CAS 196090-70-7C9H15N5O2
5-Iodo-4-methoxypyrimidine chemical structure, C5H5IN2O, CAS 219915-13-6
5-Iodo-4-methoxypyrimidine
CAS 219915-13-6C5H5IN2O
2-Trifluoromethyl-4-chloropyrimidine-5-carbonyl chloride chemical structure, C6HCl2F3N2O, CAS 188781-20-6
2-Trifluoromethyl-4-chloropyrimidine-5-carbonyl chloride
CAS 188781-20-6C6HCl2F3N2O
5-Amino-2-chloropyrimidine-4-carboxamide chemical structure, C5H5ClN4O, CAS 189747-29-3
5-Amino-2-chloropyrimidine-4-carboxamide
CAS 189747-29-3C5H5ClN4O
2-(Trifluoromethyl)pyrimidine-5-carboxylic acid chemical structure, C6H3F3N2O2, CAS 306960-77-0
2-(Trifluoromethyl)pyrimidine-5-carboxylic acid
CAS 306960-77-0C6H3F3N2O2
(4-(Ethylamino)-2-(methylthio)pyrimidin-5-yl)methanol chemical structure, C8H13N3OS, CAS 185040-34-0
(4-(Ethylamino)-2-(methylthio)pyrimidin-5-yl)methanol
CAS 185040-34-0C8H13N3OS
2-Cyano-4-trifluoromethylpyrimidine-5-carboxylic acid chemical structure, C7H2F3N3O2, CAS 188781-47-7
2-Cyano-4-trifluoromethylpyrimidine-5-carboxylic acid
CAS 188781-47-7C7H2F3N3O2
4-[(1-Methylpropyl)amino]-2-(methylthio)-5-pyrimidinemethanol chemical structure, C10H17N3OS, CAS 1025907-15-6
4-[(1-Methylpropyl)amino]-2-(methylthio)-5-pyrimidinemethanol
CAS 1025907-15-6C10H17N3OS
2,6-Dimethoxy-5-nitro-4-pyrimidinecarboxylic acid chemical structure, C7H7N3O6, CAS 226559-53-1
2,6-Dimethoxy-5-nitro-4-pyrimidinecarboxylic acid
CAS 226559-53-1C7H7N3O6