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Murcko scaffold

Ring system with 2 rings and 11 atoms

49 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
49
With full pages
3
Scaffold SMILES

C1=NC(c2ccccc2)CO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1=NC(c2ccccc2)CO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 49 chemicals

Rexamino chemical structure, C9H10N2O, CAS 52883-35-9
Rexamino
CAS 52883-35-9C9H10N2O
(4R)-2-Methyl-4-phenyl-4,5-dihydro-1,3-oxazole chemical structure, C10H11NO, CAS 116173-81-0
(4R)-2-Methyl-4-phenyl-4,5-dihydro-1,3-oxazole
CAS 116173-81-0C10H11NO
Oxazole, 2-(1,1-dimethylethyl)-4,5-dihydro-4-phenyl-, (R)- chemical structure, C13H17NO, CAS 168034-01-3
Oxazole, 2-(1,1-dimethylethyl)-4,5-dihydro-4-phenyl-, (R)-
CAS 168034-01-3C13H17NO
(S)-Rexamino chemical structure, C9H10N2O, CAS 165035-65-4
(S)-Rexamino
CAS 165035-65-4C9H10N2O
(4R)-4-Phenyl-2-oxazoline chemical structure, C9H9NO, CAS 132377-01-6
(4R)-4-Phenyl-2-oxazoline
CAS 132377-01-6C9H9NO
4,5-Dihydro-5-methyl-4-phenyl-2-oxazolamine chemical structure, C10H12N2O, CAS 90917-82-1
4,5-Dihydro-5-methyl-4-phenyl-2-oxazolamine
CAS 90917-82-1C10H12N2O
(4S,5R)-4,5-Dihydro-5-methyl-4-phenyl-2-oxazolamine chemical structure, C10H12N2O, CAS 1257614-47-3
(4S,5R)-4,5-Dihydro-5-methyl-4-phenyl-2-oxazolamine
CAS 1257614-47-3C10H12N2O
rel-(4R,5R)-4,5-Dihydro-5-methyl-4-phenyl-2-oxazolamine chemical structure, C10H12N2O, CAS 63204-72-8
rel-(4R,5R)-4,5-Dihydro-5-methyl-4-phenyl-2-oxazolamine
CAS 63204-72-8C10H12N2O
(4R)-2-(Chloromethyl)-4-phenyl-4,5-dihydro-1,3-oxazole chemical structure, C10H10ClNO, CAS 221196-89-0
(4R)-2-(Chloromethyl)-4-phenyl-4,5-dihydro-1,3-oxazole
CAS 221196-89-0C10H10ClNO
4-(4-Fluorophenyl)-4,5-dihydrooxazol-2-amine chemical structure, C9H9FN2O, CAS 81880-01-5
4-(4-Fluorophenyl)-4,5-dihydrooxazol-2-amine
CAS 81880-01-5C9H9FN2O
(S)-4-(4-Chlorophenyl)-4,5-dihydrooxazol-2-amine chemical structure, C9H9ClN2O, CAS 1043493-37-3
(S)-4-(4-Chlorophenyl)-4,5-dihydrooxazol-2-amine
CAS 1043493-37-3C9H9ClN2O
(4S)-4-(2,4-Difluorophenyl)-4,5-dihydro-1,3-oxazol-2-amine chemical structure, C9H8F2N2O, CAS 1043489-40-2
(4S)-4-(2,4-Difluorophenyl)-4,5-dihydro-1,3-oxazol-2-amine
CAS 1043489-40-2C9H8F2N2O
(S)-4-(3,4-Dichlorophenyl)-4,5-dihydrooxazol-2-amine chemical structure, C9H8Cl2N2O, CAS 1043491-54-8
(S)-4-(3,4-Dichlorophenyl)-4,5-dihydrooxazol-2-amine
CAS 1043491-54-8C9H8Cl2N2O
(S)-4-(4-Bromophenyl)-4,5-dihydrooxazol-2-amine chemical structure, C9H9BrN2O, CAS 1043491-86-6
(S)-4-(4-Bromophenyl)-4,5-dihydrooxazol-2-amine
CAS 1043491-86-6C9H9BrN2O
(S)-4-(3-Chloro-4-fluorophenyl)-4,5-dihydrooxazol-2-amine chemical structure, C9H8ClFN2O, CAS 1043493-49-7
(S)-4-(3-Chloro-4-fluorophenyl)-4,5-dihydrooxazol-2-amine
CAS 1043493-49-7C9H8ClFN2O
(S)-4-(3-Chloro-5-fluorophenyl)-4,5-dihydrooxazol-2-amine chemical structure, C9H8ClFN2O, CAS 1043493-71-5
(S)-4-(3-Chloro-5-fluorophenyl)-4,5-dihydrooxazol-2-amine
CAS 1043493-71-5C9H8ClFN2O
(S)-4-[3-(Trifluoromethyl)phenyl]-4,5-dihydrooxazol-2-amine chemical structure, C10H9F3N2O, CAS 1043492-90-5
(S)-4-[3-(Trifluoromethyl)phenyl]-4,5-dihydrooxazol-2-amine
CAS 1043492-90-5C10H9F3N2O
RO-5263397 chemical structure, C10H11FN2O, CAS 1357266-05-7
RO-5263397
CAS 1357266-05-7C10H11FN2O
4-(3,5-Dichlorophenyl)-4,5-dihydrooxazol-2-amine chemical structure, C9H8Cl2N2O, CAS 1043494-00-3
4-(3,5-Dichlorophenyl)-4,5-dihydrooxazol-2-amine
CAS 1043494-00-3C9H8Cl2N2O
(S)-4-(3-Fluorophenyl)-4,5-dihydrooxazol-2-amine chemical structure, C9H9FN2O, CAS 1043494-23-0
(S)-4-(3-Fluorophenyl)-4,5-dihydrooxazol-2-amine
CAS 1043494-23-0C9H9FN2O
4-(4-Chlorophenyl)-4,5-dihydrooxazol-2-amine chemical structure, C9H9ClN2O, CAS 1043488-74-9
4-(4-Chlorophenyl)-4,5-dihydrooxazol-2-amine
CAS 1043488-74-9C9H9ClN2O
4-(3-Chlorophenyl)-4,5-dihydrooxazol-2-amine chemical structure, C9H9ClN2O, CAS 1043493-88-4
4-(3-Chlorophenyl)-4,5-dihydrooxazol-2-amine
CAS 1043493-88-4C9H9ClN2O
4-(3-Fluoro-2-methylphenyl)-4,5-dihydrooxazol-2-amine chemical structure, C10H11FN2O, CAS 1043498-53-8
4-(3-Fluoro-2-methylphenyl)-4,5-dihydrooxazol-2-amine
CAS 1043498-53-8C10H11FN2O
(S)-4-(3-Chlorophenyl)-4,5-dihydrooxazol-2-amine chemical structure, C9H9ClN2O, CAS 1043494-09-2
(S)-4-(3-Chlorophenyl)-4,5-dihydrooxazol-2-amine
CAS 1043494-09-2C9H9ClN2O