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Murcko scaffold

Ring system with 2 rings and 14 atoms

30 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
30
With full pages
6
Scaffold SMILES

O=C(Nc1nncs1)C1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1nncs1)C1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 30 of 30 chemicals

N-(5-Ethyl-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide chemical structure, C11H17N3OS, CAS 312754-89-5
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide
CAS 312754-89-5C11H17N3OS
N-(5-(Methoxymethyl)-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide chemical structure, C11H17N3O2S, CAS 685847-69-2
N-(5-(Methoxymethyl)-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide
CAS 685847-69-2C11H17N3O2S
N-[5-(2-Methylpropyl)-1,3,4-thiadiazol-2-yl]cyclohexanecarboxamide chemical structure, C13H21N3OS, CAS 510737-07-2
N-[5-(2-Methylpropyl)-1,3,4-thiadiazol-2-yl]cyclohexanecarboxamide
CAS 510737-07-2C13H21N3OS
N-(5-Isopropyl-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide chemical structure, C12H19N3OS, CAS 353467-82-0
N-(5-Isopropyl-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide
CAS 353467-82-0C12H19N3OS
N-[5-(2-Ethoxyethyl)-1,3,4-thiadiazol-2-yl]cyclohexanecarboxamide chemical structure, C13H21N3O2S, CAS 702647-42-5
N-[5-(2-Ethoxyethyl)-1,3,4-thiadiazol-2-yl]cyclohexanecarboxamide
CAS 702647-42-5C13H21N3O2S
4-Butyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)cyclohexane-1-carboxamide chemical structure, C14H23N3OS, CAS 714262-22-3
4-Butyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)cyclohexane-1-carboxamide
CAS 714262-22-3C14H23N3OS
4-Butyl-N-(5-propyl-1,3,4-thiadiazol-2-yl)cyclohexane-1-carboxamide chemical structure, C16H27N3OS, CAS 714262-23-4
4-Butyl-N-(5-propyl-1,3,4-thiadiazol-2-yl)cyclohexane-1-carboxamide
CAS 714262-23-4C16H27N3OS
4-Butyl-N-(5-(methylthio)-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide chemical structure, C14H23N3OS2, CAS 391875-84-6
4-Butyl-N-(5-(methylthio)-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide
CAS 391875-84-6C14H23N3OS2
4-Butyl-N-(5-ethylsulfanyl-1,3,4-thiadiazol-2-yl)cyclohexane-1-carboxamide chemical structure, C15H25N3OS2, CAS 827008-79-7
4-Butyl-N-(5-ethylsulfanyl-1,3,4-thiadiazol-2-yl)cyclohexane-1-carboxamide
CAS 827008-79-7C15H25N3OS2
2-[(5-Methyl-1,3,4-thiadiazol-2-yl)carbamoyl]cyclohexane-1-carboxylic acid chemical structure, C11H15N3O3S, CAS 560107-29-1
2-[(5-Methyl-1,3,4-thiadiazol-2-yl)carbamoyl]cyclohexane-1-carboxylic acid
CAS 560107-29-1C11H15N3O3S
N-(5-Methyl-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide chemical structure, C10H15N3OS, CAS 313517-87-2
N-(5-Methyl-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide
CAS 313517-87-2C10H15N3OS
4-Butyl-N-(5-(butylthio)-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide chemical structure, C17H29N3OS2, CAS 391875-99-3
4-Butyl-N-(5-(butylthio)-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide
CAS 391875-99-3C17H29N3OS2
2-({[5-(Ethylsulfanyl)-1,3,4-thiadiazol-2-yl]amino}carbonyl)cyclohexanecarboxylic acid chemical structure, C12H17N3O3S2, CAS 438528-65-5
2-({[5-(Ethylsulfanyl)-1,3,4-thiadiazol-2-yl]amino}carbonyl)cyclohexanecarboxylic acid
CAS 438528-65-5C12H17N3O3S2
4-Butyl-N-(5-(sec-butylthio)-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide chemical structure, C17H29N3OS2, CAS 474621-50-6
4-Butyl-N-(5-(sec-butylthio)-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide
CAS 474621-50-6C17H29N3OS2
Ethyl 2-((5-(cyclohexanecarboxamido)-1,3,4-thiadiazol-2-yl)thio)acetate chemical structure, C13H19N3O3S2, CAS 392317-97-4
Ethyl 2-((5-(cyclohexanecarboxamido)-1,3,4-thiadiazol-2-yl)thio)acetate
CAS 392317-97-4C13H19N3O3S2
4-Butyl-N-(5-(isopropylthio)-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide chemical structure, C16H27N3OS2, CAS 391875-69-7
4-Butyl-N-(5-(isopropylthio)-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide
CAS 391875-69-7C16H27N3OS2
4-Butyl-N-(5-(propylthio)-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide chemical structure, C16H27N3OS2, CAS 391875-35-7
4-Butyl-N-(5-(propylthio)-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide
CAS 391875-35-7C16H27N3OS2
N-(5-(Methylthio)-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide chemical structure, C10H15N3OS2, CAS 393565-62-3
N-(5-(Methylthio)-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide
CAS 393565-62-3C10H15N3OS2
N-(5-Butan-2-ylsulfanyl-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide chemical structure, C13H21N3OS2, CAS 893233-36-8
N-(5-Butan-2-ylsulfanyl-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide
CAS 893233-36-8C13H21N3OS2
N-(5-Propylsulfanyl-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide chemical structure, C12H19N3OS2, CAS 393565-63-4
N-(5-Propylsulfanyl-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide
CAS 393565-63-4C12H19N3OS2
N-[5-(2-Amino-2-oxoethyl)sulfanyl-1,3,4-thiadiazol-2-yl]cyclohexanecarboxamide chemical structure, C11H16N4O2S2, CAS 868972-80-9
N-[5-(2-Amino-2-oxoethyl)sulfanyl-1,3,4-thiadiazol-2-yl]cyclohexanecarboxamide
CAS 868972-80-9C11H16N4O2S2
4-Butyl-N-[5-(ethylsulfonyl)-1,3,4-thiadiazol-2-yl]cyclohexanecarboxamide chemical structure, C15H25N3O3S2, CAS 892627-46-2
4-Butyl-N-[5-(ethylsulfonyl)-1,3,4-thiadiazol-2-yl]cyclohexanecarboxamide
CAS 892627-46-2C15H25N3O3S2
4-Butyl-N-[5-(butylsulfonyl)-1,3,4-thiadiazol-2-yl]cyclohexanecarboxamide chemical structure, C17H29N3O3S2, CAS 898525-19-4
4-Butyl-N-[5-(butylsulfonyl)-1,3,4-thiadiazol-2-yl]cyclohexanecarboxamide
CAS 898525-19-4C17H29N3O3S2
4-Butyl-N-[5-(propylsulfonyl)-1,3,4-thiadiazol-2-yl]cyclohexanecarboxamide chemical structure, C16H27N3O3S2, CAS 898643-71-5
4-Butyl-N-[5-(propylsulfonyl)-1,3,4-thiadiazol-2-yl]cyclohexanecarboxamide
CAS 898643-71-5C16H27N3O3S2