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Murcko scaffold

Ring system with 3 rings and 27 atoms

17 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
27
Chemicals
17
With full pages
5
Scaffold SMILES

O=S(=O)(NCCS(=O)(=O)N1CCN(c2ccccc2)CC1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(NCCS(=O)(=O)N1CCN(c2ccccc2)CC1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

2,5-Dimethoxy-N-(2-((4-phenylpiperazin-1-yl)sulfonyl)ethyl)benzenesulfonamide chemical structure, C20H27N3O6S2, CAS 933218-41-8
2,5-Dimethoxy-N-(2-((4-phenylpiperazin-1-yl)sulfonyl)ethyl)benzenesulfonamide
CAS 933218-41-8C20H27N3O6S2
2,4,6-Trimethyl-N-(2-((4-phenylpiperazin-1-yl)sulfonyl)ethyl)benzenesulfonamide chemical structure, C21H29N3O4S2, CAS 932970-85-9
2,4,6-Trimethyl-N-(2-((4-phenylpiperazin-1-yl)sulfonyl)ethyl)benzenesulfonamide
CAS 932970-85-9C21H29N3O4S2
N-(2-{[4-(4-Methoxyphenyl)piperazin-1-yl]sulfonyl}ethyl)benzenesulfonamide chemical structure, C19H25N3O5S2, CAS 897622-20-7
N-(2-{[4-(4-Methoxyphenyl)piperazin-1-yl]sulfonyl}ethyl)benzenesulfonamide
CAS 897622-20-7C19H25N3O5S2
4-Methoxy-N-(2-((4-phenylpiperazin-1-yl)sulfonyl)ethyl)benzenesulfonamide chemical structure, C19H25N3O5S2, CAS 897622-26-3
4-Methoxy-N-(2-((4-phenylpiperazin-1-yl)sulfonyl)ethyl)benzenesulfonamide
CAS 897622-26-3C19H25N3O5S2
4-Fluoro-N-(2-((4-(2-fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)benzenesulfonamide chemical structure, C18H21F2N3O4S2, CAS 897622-13-8
4-Fluoro-N-(2-((4-(2-fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)benzenesulfonamide
CAS 897622-13-8C18H21F2N3O4S2
N-(2-((4-(4-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)benzenesulfonamide chemical structure, C18H22FN3O4S2, CAS 897622-16-1
N-(2-((4-(4-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)benzenesulfonamide
CAS 897622-16-1C18H22FN3O4S2
N-(2-{[4-(4-Fluorophenyl)piperazin-1-yl]sulfonyl}ethyl)-4-methylbenzene-1-sulfonamide chemical structure, C19H24FN3O4S2, CAS 897622-17-2
N-(2-{[4-(4-Fluorophenyl)piperazin-1-yl]sulfonyl}ethyl)-4-methylbenzene-1-sulfonamide
CAS 897622-17-2C19H24FN3O4S2
4-Fluoro-N-(2-((4-(4-fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)benzenesulfonamide chemical structure, C18H21F2N3O4S2, CAS 897622-18-3
4-Fluoro-N-(2-((4-(4-fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)benzenesulfonamide
CAS 897622-18-3C18H21F2N3O4S2
4-Fluoro-N-(2-((4-phenylpiperazin-1-yl)sulfonyl)ethyl)benzenesulfonamide chemical structure, C18H22FN3O4S2, CAS 897622-25-2
4-Fluoro-N-(2-((4-phenylpiperazin-1-yl)sulfonyl)ethyl)benzenesulfonamide
CAS 897622-25-2C18H22FN3O4S2
4-Chloro-N-(2-{[4-(4-fluorophenyl)piperazin-1-yl]sulfonyl}ethyl)benzene-1-sulfonamide chemical structure, C18H21ClFN3O4S2, CAS 933218-20-3
4-Chloro-N-(2-{[4-(4-fluorophenyl)piperazin-1-yl]sulfonyl}ethyl)benzene-1-sulfonamide
CAS 933218-20-3C18H21ClFN3O4S2
2,5-Difluoro-N-(2-{[4-(4-fluorophenyl)piperazin-1-yl]sulfonyl}ethyl)benzene-1-sulfonamide chemical structure, C18H20F3N3O4S2, CAS 946308-07-2
2,5-Difluoro-N-(2-{[4-(4-fluorophenyl)piperazin-1-yl]sulfonyl}ethyl)benzene-1-sulfonamide
CAS 946308-07-2C18H20F3N3O4S2
N-(2-{[4-(4-Fluorophenyl)piperazin-1-yl]sulfonyl}ethyl)-2,5-dimethoxybenzene-1-sulfonamide chemical structure, C20H26FN3O6S2, CAS 932970-73-5
N-(2-{[4-(4-Fluorophenyl)piperazin-1-yl]sulfonyl}ethyl)-2,5-dimethoxybenzene-1-sulfonamide
CAS 932970-73-5C20H26FN3O6S2
4-Fluoro-N-(2-{[4-(4-methoxyphenyl)piperazin-1-yl]sulfonyl}ethyl)benzene-1-sulfonamide chemical structure, C19H24FN3O5S2, CAS 932970-76-8
4-Fluoro-N-(2-{[4-(4-methoxyphenyl)piperazin-1-yl]sulfonyl}ethyl)benzene-1-sulfonamide
CAS 932970-76-8C19H24FN3O5S2
N-{4-[(2-{[4-(4-Methoxyphenyl)piperazin-1-yl]sulfonyl}ethyl)sulfamoyl]phenyl}acetamide chemical structure, C21H28N4O6S2, CAS 933218-30-5
N-{4-[(2-{[4-(4-Methoxyphenyl)piperazin-1-yl]sulfonyl}ethyl)sulfamoyl]phenyl}acetamide
CAS 933218-30-5C21H28N4O6S2
2,5-Dimethoxy-N-(2-{[4-(4-methoxyphenyl)piperazin-1-yl]sulfonyl}ethyl)benzene-1-sulfonamide chemical structure, C21H29N3O7S2, CAS 933028-13-8
2,5-Dimethoxy-N-(2-{[4-(4-methoxyphenyl)piperazin-1-yl]sulfonyl}ethyl)benzene-1-sulfonamide
CAS 933028-13-8C21H29N3O7S2
2,5-Dimethoxy-N-(2-{[4-(2-methoxyphenyl)piperazin-1-yl]sulfonyl}ethyl)benzene-1-sulfonamide chemical structure, C21H29N3O7S2, CAS 933028-16-1
2,5-Dimethoxy-N-(2-{[4-(2-methoxyphenyl)piperazin-1-yl]sulfonyl}ethyl)benzene-1-sulfonamide
CAS 933028-16-1C21H29N3O7S2
N-(2-((4-(2-Methoxyphenyl)piperazin-1-yl)sulfonyl)ethyl)-4-nitrobenzenesulfonamide chemical structure, C19H24N4O7S2, CAS 933218-34-9
N-(2-((4-(2-Methoxyphenyl)piperazin-1-yl)sulfonyl)ethyl)-4-nitrobenzenesulfonamide
CAS 933218-34-9C19H24N4O7S2