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Murcko scaffold

Ring system with 3 rings and 25 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
14
With full pages
3
Scaffold SMILES

O=C(Cc1ccccc1)OCC(=O)N1CCN(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccccc1)OCC(=O)N1CCN(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

[2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl] 2-(2-chloro-6-fluorophenyl)acetate chemical structure, C20H20ClFN2O3, CAS 562845-73-2
[2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl] 2-(2-chloro-6-fluorophenyl)acetate
CAS 562845-73-2C20H20ClFN2O3
2-[4-(4-Methoxyphenyl)piperazin-1-yl]-2-oxoethyl 2-(3-methoxyphenyl)acetate chemical structure, C22H26N2O5, CAS 1002925-08-7
2-[4-(4-Methoxyphenyl)piperazin-1-yl]-2-oxoethyl 2-(3-methoxyphenyl)acetate
CAS 1002925-08-7C22H26N2O5
[2-[4-(4-Methoxyphenyl)piperazin-1-yl]-2-oxoethyl] 2-(3-fluorophenyl)acetate chemical structure, C21H23FN2O4, CAS 1794909-26-4
[2-[4-(4-Methoxyphenyl)piperazin-1-yl]-2-oxoethyl] 2-(3-fluorophenyl)acetate
CAS 1794909-26-4C21H23FN2O4
2-[4-(4-Methoxyphenyl)piperazin-1-yl]-2-oxoethyl (4-methylphenyl)acetate chemical structure, C22H26N2O4, CAS 1798043-68-1
2-[4-(4-Methoxyphenyl)piperazin-1-yl]-2-oxoethyl (4-methylphenyl)acetate
CAS 1798043-68-1C22H26N2O4
2-[4-(2-Fluorophenyl)piperazin-1-yl]-2-oxoethyl (4-methylphenyl)acetate chemical structure, C21H23FN2O3, CAS 1797043-49-2
2-[4-(2-Fluorophenyl)piperazin-1-yl]-2-oxoethyl (4-methylphenyl)acetate
CAS 1797043-49-2C21H23FN2O3
[2-[4-(2-Methoxyphenyl)piperazin-1-yl]-2-oxoethyl] 2-(4-chlorophenyl)acetate chemical structure, C21H23ClN2O4, CAS 1794850-24-0
[2-[4-(2-Methoxyphenyl)piperazin-1-yl]-2-oxoethyl] 2-(4-chlorophenyl)acetate
CAS 1794850-24-0C21H23ClN2O4
2-[4-(4-Methoxyphenyl)piperazin-1-yl]-2-oxoethyl 2-phenylbutanoate chemical structure, C23H28N2O4, CAS 879139-93-2
2-[4-(4-Methoxyphenyl)piperazin-1-yl]-2-oxoethyl 2-phenylbutanoate
CAS 879139-93-2C23H28N2O4
2-[4-(4-Fluorophenyl)piperazin-1-yl]-2-oxoethyl (4-methylphenyl)acetate chemical structure, C21H23FN2O3, CAS 1798016-84-8
2-[4-(4-Fluorophenyl)piperazin-1-yl]-2-oxoethyl (4-methylphenyl)acetate
CAS 1798016-84-8C21H23FN2O3
2-[4-(2-Fluorophenyl)piperazin-1-yl]-2-oxoethyl 2-(4-chlorophenyl)acetate chemical structure, C20H20ClFN2O3, CAS 1794798-16-5
2-[4-(2-Fluorophenyl)piperazin-1-yl]-2-oxoethyl 2-(4-chlorophenyl)acetate
CAS 1794798-16-5C20H20ClFN2O3
2-[4-(2-Fluorophenyl)piperazin-1-yl]-2-oxoethyl 2-phenylbutanoate chemical structure, C22H25FN2O3, CAS 1295229-92-3
2-[4-(2-Fluorophenyl)piperazin-1-yl]-2-oxoethyl 2-phenylbutanoate
CAS 1295229-92-3C22H25FN2O3
2-[4-(4-Fluorophenyl)piperazin-1-yl]-2-oxoethyl 2-phenylbutanoate chemical structure, C22H25FN2O3, CAS 1794850-17-1
2-[4-(4-Fluorophenyl)piperazin-1-yl]-2-oxoethyl 2-phenylbutanoate
CAS 1794850-17-1C22H25FN2O3
2-(4-(2-Methoxyphenyl)piperazin-1-yl)-2-oxoethyl 2-phenylbutanoate chemical structure, C23H28N2O4, CAS 1794751-03-3
2-(4-(2-Methoxyphenyl)piperazin-1-yl)-2-oxoethyl 2-phenylbutanoate
CAS 1794751-03-3C23H28N2O4
2-[4-(4-Methoxyphenyl)piperazin-1-yl]-2-oxoethyl (4-ethoxyphenyl)acetate chemical structure, C23H28N2O5, CAS 1327385-32-9
2-[4-(4-Methoxyphenyl)piperazin-1-yl]-2-oxoethyl (4-ethoxyphenyl)acetate
CAS 1327385-32-9C23H28N2O5
2-[4-(4-Fluorophenyl)piperazin-1-yl]-2-oxoethyl (4-ethoxyphenyl)acetate chemical structure, C22H25FN2O4, CAS 1794781-01-3
2-[4-(4-Fluorophenyl)piperazin-1-yl]-2-oxoethyl (4-ethoxyphenyl)acetate
CAS 1794781-01-3C22H25FN2O4