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Murcko scaffold

Ring system with 4 rings and 27 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
6
With full pages
1
Scaffold SMILES

O=C(Nc1nnc(-c2ccccc2)o1)c1ccc(N2C(=O)CCC2=O)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1nnc(-c2ccccc2)o1)c1ccc(N2C(=O)CCC2=O)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

N-[5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl]-4-(2,5-dioxopyrrolidin-1-yl)benzamide chemical structure, C19H13ClN4O4, CAS 865287-13-4
N-[5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl]-4-(2,5-dioxopyrrolidin-1-yl)benzamide
CAS 865287-13-4C19H13ClN4O4
4-(2,5-Dioxopyrrolidin-1-yl)-N-[5-(3,4,5-triethoxyphenyl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C25H26N4O7, CAS 891126-45-7
4-(2,5-Dioxopyrrolidin-1-yl)-N-[5-(3,4,5-triethoxyphenyl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 891126-45-7C25H26N4O7
N-[5-(4-Bromophenyl)-1,3,4-oxadiazol-2-yl]-4-(2,5-dioxopyrrolidin-1-yl)benzamide chemical structure, C19H13BrN4O4, CAS 905677-58-9
N-[5-(4-Bromophenyl)-1,3,4-oxadiazol-2-yl]-4-(2,5-dioxopyrrolidin-1-yl)benzamide
CAS 905677-58-9C19H13BrN4O4
4-(2,5-Dioxopyrrolidin-1-yl)-N-(5-(4-(methylsulfonyl)phenyl)-1,3,4-oxadiazol-2-yl)benzamide chemical structure, C20H16N4O6S, CAS 886911-23-5
4-(2,5-Dioxopyrrolidin-1-yl)-N-(5-(4-(methylsulfonyl)phenyl)-1,3,4-oxadiazol-2-yl)benzamide
CAS 886911-23-5C20H16N4O6S
4-(2,5-Dioxopyrrolidin-1-yl)-N-(5-(3-(methylsulfonyl)phenyl)-1,3,4-oxadiazol-2-yl)benzamide chemical structure, C20H16N4O6S, CAS 886929-25-5
4-(2,5-Dioxopyrrolidin-1-yl)-N-(5-(3-(methylsulfonyl)phenyl)-1,3,4-oxadiazol-2-yl)benzamide
CAS 886929-25-5C20H16N4O6S
N-[5-(2,4-Difluorophenyl)-1,3,4-oxadiazol-2-yl]-4-(2,5-dioxopyrrolidin-1-yl)benzamide chemical structure, C19H12F2N4O4, CAS 1170020-32-2
N-[5-(2,4-Difluorophenyl)-1,3,4-oxadiazol-2-yl]-4-(2,5-dioxopyrrolidin-1-yl)benzamide
CAS 1170020-32-2C19H12F2N4O4