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Murcko scaffold

Ring system with 3 rings and 23 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
8
With full pages
3
Scaffold SMILES

O=S(=O)(Nc1ccccc1Sc1ccccn1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(Nc1ccccc1Sc1ccccn1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

N-(2-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]sulfanyl}phenyl)-4-fluorobenzenesulfonamide chemical structure, C18H11ClF4N2O2S2, CAS 338773-45-8
N-(2-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]sulfanyl}phenyl)-4-fluorobenzenesulfonamide
CAS 338773-45-8C18H11ClF4N2O2S2
Methyl 6-{[2-({[4-(acetylamino)phenyl]sulfonyl}amino)phenyl]sulfanyl}nicotinate chemical structure, C21H19N3O5S2, CAS 478033-25-9
Methyl 6-{[2-({[4-(acetylamino)phenyl]sulfonyl}amino)phenyl]sulfanyl}nicotinate
CAS 478033-25-9C21H19N3O5S2
4-Chloro-N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanylphenyl]benzenesulfonamide chemical structure, C18H11Cl2F3N2O2S2, CAS 338407-77-5
4-Chloro-N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanylphenyl]benzenesulfonamide
CAS 338407-77-5C18H11Cl2F3N2O2S2
Methyl 6-[(2-{[(4-methylphenyl)sulfonyl]amino}phenyl)sulfanyl]nicotinate chemical structure, C20H18N2O4S2, CAS 478033-23-7
Methyl 6-[(2-{[(4-methylphenyl)sulfonyl]amino}phenyl)sulfanyl]nicotinate
CAS 478033-23-7C20H18N2O4S2
Methyl 6-[(2-{[(4-methoxyphenyl)sulfonyl]amino}phenyl)sulfanyl]nicotinate chemical structure, C20H18N2O5S2, CAS 478033-22-6
Methyl 6-[(2-{[(4-methoxyphenyl)sulfonyl]amino}phenyl)sulfanyl]nicotinate
CAS 478033-22-6C20H18N2O5S2
N-{2-[(3-Cyano-4,6-dimethyl-2-pyridinyl)sulfanyl]phenyl}-4-methoxybenzenesulfonamide chemical structure, C21H19N3O3S2, CAS 478033-63-5
N-{2-[(3-Cyano-4,6-dimethyl-2-pyridinyl)sulfanyl]phenyl}-4-methoxybenzenesulfonamide
CAS 478033-63-5C21H19N3O3S2
2,5-Dichloro-N-{2-[(3-cyano-4,6-dimethyl-2-pyridinyl)sulfanyl]phenyl}benzenesulfonamide chemical structure, C20H15Cl2N3O2S2, CAS 478033-64-6
2,5-Dichloro-N-{2-[(3-cyano-4,6-dimethyl-2-pyridinyl)sulfanyl]phenyl}benzenesulfonamide
CAS 478033-64-6C20H15Cl2N3O2S2
Methyl 6-[(2-{[(4-chlorophenyl)sulfonyl]amino}phenyl)sulfanyl]nicotinate chemical structure, C19H15ClN2O4S2, CAS 478033-24-8
Methyl 6-[(2-{[(4-chlorophenyl)sulfonyl]amino}phenyl)sulfanyl]nicotinate
CAS 478033-24-8C19H15ClN2O4S2