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Murcko scaffold

Ring system with 3 rings and 23 atoms

28 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
28
With full pages
10
Scaffold SMILES

O=C(Nc1ccccc1C(=O)N1CCNCC1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1C(=O)N1CCNCC1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

4-Methyl-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]benzamide chemical structure, C20H23N3O2, CAS 328280-80-4
4-Methyl-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]benzamide
CAS 328280-80-4C20H23N3O2
2-Fluoro-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]benzamide chemical structure, C19H20FN3O2, CAS 328286-02-8
2-Fluoro-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]benzamide
CAS 328286-02-8C19H20FN3O2
2-Methyl-N-{2-[(4-methyl-1-piperazinyl)carbonyl]phenyl}benzamide chemical structure, C20H23N3O2, CAS 309952-20-3
2-Methyl-N-{2-[(4-methyl-1-piperazinyl)carbonyl]phenyl}benzamide
CAS 309952-20-3C20H23N3O2
N-[2-(4-Methylpiperazine-1-carbonyl)phenyl]benzamide chemical structure, C19H21N3O2, CAS 312289-86-4
N-[2-(4-Methylpiperazine-1-carbonyl)phenyl]benzamide
CAS 312289-86-4C19H21N3O2
2,4-Dichloro-N-[2,4-dichloro-6-[4-(2-hydroxyethyl)piperazine-1-carbonyl]phenyl]benzamide chemical structure, C20H19Cl4N3O3, CAS 667889-78-3
2,4-Dichloro-N-[2,4-dichloro-6-[4-(2-hydroxyethyl)piperazine-1-carbonyl]phenyl]benzamide
CAS 667889-78-3C20H19Cl4N3O3
2,4-Dichloro-N-[2-[4-(2-hydroxyethyl)piperazine-1-carbonyl]phenyl]benzamide chemical structure, C20H21Cl2N3O3, CAS 667890-00-8
2,4-Dichloro-N-[2-[4-(2-hydroxyethyl)piperazine-1-carbonyl]phenyl]benzamide
CAS 667890-00-8C20H21Cl2N3O3
2,4-Dichloro-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]benzamide chemical structure, C19H19Cl2N3O2, CAS 332848-91-6
2,4-Dichloro-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]benzamide
CAS 332848-91-6C19H19Cl2N3O2
2-Chloro-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]benzamide chemical structure, C19H20ClN3O2, CAS 329067-29-0
2-Chloro-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]benzamide
CAS 329067-29-0C19H20ClN3O2
4-Chloro-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]benzamide chemical structure, C19H20ClN3O2, CAS 352646-67-4
4-Chloro-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]benzamide
CAS 352646-67-4C19H20ClN3O2
2,4-Dichloro-N-[2,4-dichloro-6-(4-methylpiperazine-1-carbonyl)phenyl]benzamide chemical structure, C19H17Cl4N3O2, CAS 693254-01-2
2,4-Dichloro-N-[2,4-dichloro-6-(4-methylpiperazine-1-carbonyl)phenyl]benzamide
CAS 693254-01-2C19H17Cl4N3O2
Ethyl 4-[2-[(4-tert-butylbenzoyl)amino]benzoyl]piperazine-1-carboxylate chemical structure, C25H31N3O4, CAS 433703-54-9
Ethyl 4-[2-[(4-tert-butylbenzoyl)amino]benzoyl]piperazine-1-carboxylate
CAS 433703-54-9C25H31N3O4
Ethyl 4-{2-[(4-methoxybenzoyl)amino]benzoyl}-1-piperazinecarboxylate chemical structure, C22H25N3O5, CAS 693228-60-3
Ethyl 4-{2-[(4-methoxybenzoyl)amino]benzoyl}-1-piperazinecarboxylate
CAS 693228-60-3C22H25N3O5
Ethyl 4-{5-chloro-2-[(4-methoxybenzoyl)amino]benzoyl}-1-piperazinecarboxylate chemical structure, C22H24ClN3O5, CAS 693231-39-9
Ethyl 4-{5-chloro-2-[(4-methoxybenzoyl)amino]benzoyl}-1-piperazinecarboxylate
CAS 693231-39-9C22H24ClN3O5
3,4,5-Trimethoxy-N-{2-[(4-methyl-1-piperazinyl)carbonyl]phenyl}benzamide chemical structure, C22H27N3O5, CAS 815623-08-6
3,4,5-Trimethoxy-N-{2-[(4-methyl-1-piperazinyl)carbonyl]phenyl}benzamide
CAS 815623-08-6C22H27N3O5
2-Bromo-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]benzamide chemical structure, C19H20BrN3O2, CAS 815622-85-6
2-Bromo-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]benzamide
CAS 815622-85-6C19H20BrN3O2
4-tert-Butyl-N-{2-[(4-methyl-1-piperazinyl)carbonyl]phenyl}benzamide chemical structure, C23H29N3O2, CAS 815623-24-6
4-tert-Butyl-N-{2-[(4-methyl-1-piperazinyl)carbonyl]phenyl}benzamide
CAS 815623-24-6C23H29N3O2
3-Chloro-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]benzamide chemical structure, C19H20ClN3O2, CAS 815623-49-5
3-Chloro-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]benzamide
CAS 815623-49-5C19H20ClN3O2
4-Ethoxy-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]benzamide chemical structure, C21H25N3O3, CAS 875053-27-3
4-Ethoxy-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]benzamide
CAS 875053-27-3C21H25N3O3
4-Isopropoxy-N-{2-[(4-methyl-1-piperazinyl)carbonyl]phenyl}benzamide chemical structure, C22H27N3O3, CAS 880563-99-5
4-Isopropoxy-N-{2-[(4-methyl-1-piperazinyl)carbonyl]phenyl}benzamide
CAS 880563-99-5C22H27N3O3
3-Ethoxy-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]benzamide chemical structure, C21H25N3O3, CAS 881755-30-2
3-Ethoxy-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]benzamide
CAS 881755-30-2C21H25N3O3
N-[2-(4-Methylpiperazine-1-carbonyl)phenyl]-3-propoxybenzamide chemical structure, C22H27N3O3, CAS 881766-85-4
N-[2-(4-Methylpiperazine-1-carbonyl)phenyl]-3-propoxybenzamide
CAS 881766-85-4C22H27N3O3
Ethyl 4-[(2-{[(2-chlorophenyl)carbonyl]amino}phenyl)carbonyl]piperazine-1-carboxylate chemical structure, C21H22ClN3O4, CAS 879032-76-5
Ethyl 4-[(2-{[(2-chlorophenyl)carbonyl]amino}phenyl)carbonyl]piperazine-1-carboxylate
CAS 879032-76-5C21H22ClN3O4
2-Isopropoxy-N-{2-[(4-methyl-1-piperazinyl)carbonyl]phenyl}benzamide chemical structure, C22H27N3O3, CAS 887029-64-3
2-Isopropoxy-N-{2-[(4-methyl-1-piperazinyl)carbonyl]phenyl}benzamide
CAS 887029-64-3C22H27N3O3
Ethyl 4-[(2-{[(3-methoxyphenyl)carbonyl]amino}phenyl)carbonyl]piperazine-1-carboxylate chemical structure, C22H25N3O5, CAS 892716-69-7
Ethyl 4-[(2-{[(3-methoxyphenyl)carbonyl]amino}phenyl)carbonyl]piperazine-1-carboxylate
CAS 892716-69-7C22H25N3O5