Murcko scaffold
Ring system with 4 rings and 23 atoms
6 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 23
- Chemicals
- 6
- With full pages
- 1
Scaffold SMILES
O=c1ccc2cnc(NC3CCNCC3)nc2n1C1CCCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 6 of 6 chemicals
![8-((1R,2R)-2-Hydroxy-2-methylcyclopentyl)-2-((1-(methylsulfonyl)piperidin-4-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one chemical structure, C19H27N5O4S, CAS 2185857-89-8](/s/DVAPMYJVUZJNDK-DNVCBOLYSA-N.svg)
8-((1R,2R)-2-Hydroxy-2-methylcyclopentyl)-2-((1-(methylsulfonyl)piperidin-4-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one
CAS 2185857-89-8C19H27N5O4S
Ebvaciclib
CAS 2185857-97-8C20H27F2N5O4S
![8-((1S,2S)-2-Hydroxy-2-methylcyclopentyl)-2-((1-(methylsulfonyl)piperidin-4-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one chemical structure, C19H27N5O4S, CAS 2305711-46-8](/s/DVAPMYJVUZJNDK-KXBFYZLASA-N.svg)
8-((1S,2S)-2-Hydroxy-2-methylcyclopentyl)-2-((1-(methylsulfonyl)piperidin-4-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one
CAS 2305711-46-8C19H27N5O4S
(S)-Ebvaciclib
CAS 2185859-59-8C20H27F2N5O4S
![8-[(1R,2R)-2-Hydroxy-2-methylcyclopentyl]-6-iodo-2-[[1-(methylsulfonyl)-4-piperidyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one chemical structure, C19H26IN5O4S, CAS 2414158-90-8](/s/VYIMAIYIIBGCGH-UHFFFAOYSA-N.svg)
8-[(1R,2R)-2-Hydroxy-2-methylcyclopentyl]-6-iodo-2-[[1-(methylsulfonyl)-4-piperidyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one
CAS 2414158-90-8C19H26IN5O4S
Cdk4/6-IN-22
CAS 3036014-62-4C20H28F2N6O4S
Related scaffolds
Same ring framework with different atoms or bond orders
