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Murcko scaffold

Ring system with 4 rings and 21 atoms

32 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
32
With full pages
6
Scaffold SMILES

O=C1N=C(c2ccccc2)c2c[nH]c(-c3ccccc3)c21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1N=C(c2ccccc2)c2c[nH]c(-c3ccccc3)c21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 32 of 32 chemicals

Pigment Red 254 chemical structure, C18H10Cl2N2O2, CAS 84632-65-5
Pigment Red 254
CAS 84632-65-5C18H10Cl2N2O2
3,6-Diphenyl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione chemical structure, C18H12N2O2, CAS 54660-00-3
3,6-Diphenyl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione
CAS 54660-00-3C18H12N2O2
3-Hydroxy-1,4-bis(2-methylphenyl)-2H-pyrrolo[3,4-c]pyrrol-6-one chemical structure, C20H16N2O2, CAS 107680-83-1
3-Hydroxy-1,4-bis(2-methylphenyl)-2H-pyrrolo[3,4-c]pyrrol-6-one
CAS 107680-83-1C20H16N2O2
Benzonitrile, 3,3'-(2,3,5,6-tetrahydro-3,6-dioxopyrrolo(3,4-c)pyrrole-1,4-diyl)bis- chemical structure, C20H10N4O2, CAS 84632-50-8
Benzonitrile, 3,3'-(2,3,5,6-tetrahydro-3,6-dioxopyrrolo(3,4-c)pyrrole-1,4-diyl)bis-
CAS 84632-50-8C20H10N4O2
Pyrrolo(3,4-c)pyrrole-1,4-dione, 3,6-bis(4-bromophenyl)-2,5-dihydro- chemical structure, C18H10Br2N2O2, CAS 84632-54-2
Pyrrolo(3,4-c)pyrrole-1,4-dione, 3,6-bis(4-bromophenyl)-2,5-dihydro-
CAS 84632-54-2C18H10Br2N2O2
Pyrrolo[3,4-c]pyrrole-1,4-dione, 2,5-dihydro-2-methyl-3,6-diphenyl- chemical structure, C19H14N2O2, CAS 138369-76-3
Pyrrolo[3,4-c]pyrrole-1,4-dione, 2,5-dihydro-2-methyl-3,6-diphenyl-
CAS 138369-76-3C19H14N2O2
2,5-Dihydro-3,6-bis[4-(octadecyloxy)phenyl]pyrrolo[3,4-c]pyrrole-1,4-dione chemical structure, C54H84N2O4, CAS 850740-37-3
2,5-Dihydro-3,6-bis[4-(octadecyloxy)phenyl]pyrrolo[3,4-c]pyrrole-1,4-dione
CAS 850740-37-3C54H84N2O4
3,6-Bis-(3-(dodecylsulfonyl)phenyl)-2,5-dihydropyrrolo(3,4-C)pyrrole-1,4-dione chemical structure, C42H60N2O6S2, CAS 884862-07-1
3,6-Bis-(3-(dodecylsulfonyl)phenyl)-2,5-dihydropyrrolo(3,4-C)pyrrole-1,4-dione
CAS 884862-07-1C42H60N2O6S2
2,5-Dihydro-3,6-di-p-tolylpyrrolo(3,4-C)pyrrole-1,4-dione chemical structure, C20H16N2O2, CAS 84632-66-6
2,5-Dihydro-3,6-di-p-tolylpyrrolo(3,4-C)pyrrole-1,4-dione
CAS 84632-66-6C20H16N2O2
2,5-Dihydro-3,6-bis[4-(octadecylthio)phenyl]pyrrolo[3,4-c]pyrrole-1,4-dione chemical structure, C54H84N2O2S2, CAS 247089-62-9
2,5-Dihydro-3,6-bis[4-(octadecylthio)phenyl]pyrrolo[3,4-c]pyrrole-1,4-dione
CAS 247089-62-9C54H84N2O2S2
2,5-Dihydro-3-(4-methylphenyl)-6-[4-(octadecyloxy)phenyl]pyrrolo[3,4-c]pyrrole-1,4-dione chemical structure, C37H50N2O3, CAS 850566-76-6
2,5-Dihydro-3-(4-methylphenyl)-6-[4-(octadecyloxy)phenyl]pyrrolo[3,4-c]pyrrole-1,4-dione
CAS 850566-76-6C37H50N2O3
Pyrrolo[3,4-c]pyrrole-1,4-dione, 3-(4-chlorophenyl)-2,5-dihydro-6-phenyl- chemical structure, C18H11ClN2O2, CAS 88949-37-5
Pyrrolo[3,4-c]pyrrole-1,4-dione, 3-(4-chlorophenyl)-2,5-dihydro-6-phenyl-
CAS 88949-37-5C18H11ClN2O2
Pyrrolo(3,4-c)pyrrole-1,4-dione, 3,6-bis(4-(1,1-dimethylethyl)phenyl)-2,5-dihydro- chemical structure, C26H28N2O2, CAS 84632-59-7
Pyrrolo(3,4-c)pyrrole-1,4-dione, 3,6-bis(4-(1,1-dimethylethyl)phenyl)-2,5-dihydro-
CAS 84632-59-7C26H28N2O2
4,4'-(3,6-Dioxo-2,3,5,6-tetrahydropyrrolo[3,4-c]pyrrole-1,4-diyl)dibenzonitrile chemical structure, C20H10N4O2, CAS 84632-51-9
4,4'-(3,6-Dioxo-2,3,5,6-tetrahydropyrrolo[3,4-c]pyrrole-1,4-diyl)dibenzonitrile
CAS 84632-51-9C20H10N4O2
3,6-Bis(3-chlorophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione chemical structure, C18H10Cl2N2O2, CAS 84632-67-7
3,6-Bis(3-chlorophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione
CAS 84632-67-7C18H10Cl2N2O2
3,6-Bis(3-methoxyphenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione chemical structure, C20H16N2O4, CAS 112026-73-0
3,6-Bis(3-methoxyphenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione
CAS 112026-73-0C20H16N2O4
3-(4-Bromophenyl)-6-phenyl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione chemical structure, C18H11BrN2O2, CAS 112026-72-9
3-(4-Bromophenyl)-6-phenyl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione
CAS 112026-72-9C18H11BrN2O2
1-(3-Chlorophenyl)-4-(4-chlorophenyl)-3-hydroxy-2H-pyrrolo[3,4-c]pyrrol-6-one chemical structure, C18H10Cl2N2O2, CAS 88949-44-4
1-(3-Chlorophenyl)-4-(4-chlorophenyl)-3-hydroxy-2H-pyrrolo[3,4-c]pyrrol-6-one
CAS 88949-44-4C18H10Cl2N2O2
4,4'-(3,6-Dioxo-2,3,5,6-tetrahydropyrrolo[3,4-c]pyrrole-1,4-diyl)dibenzenesulfonyl chloride chemical structure, C18H10Cl2N2O6S2, CAS 110893-38-4
4,4'-(3,6-Dioxo-2,3,5,6-tetrahydropyrrolo[3,4-c]pyrrole-1,4-diyl)dibenzenesulfonyl chloride
CAS 110893-38-4C18H10Cl2N2O6S2
4,4a(2)-(2,3,5,6-Tetrahydro-3,6-dioxopyrrolo[3,4-c]pyrrole-1,4-diyl)bis[benzenesulfonic acid] chemical structure, C18H12N2O8S2, CAS 110893-39-5
4,4a(2)-(2,3,5,6-Tetrahydro-3,6-dioxopyrrolo[3,4-c]pyrrole-1,4-diyl)bis[benzenesulfonic acid]
CAS 110893-39-5C18H12N2O8S2
4-(4-Fluorophenyl)-3-hydroxy-1-phenyl-2H-pyrrolo[3,4-c]pyrrol-6-one chemical structure, C18H11FN2O2, CAS 128454-81-9
4-(4-Fluorophenyl)-3-hydroxy-1-phenyl-2H-pyrrolo[3,4-c]pyrrol-6-one
CAS 128454-81-9C18H11FN2O2
3,6-Bis(4-fluorophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione chemical structure, C18H10F2N2O2, CAS 84632-57-5
3,6-Bis(4-fluorophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione
CAS 84632-57-5C18H10F2N2O2
3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione chemical structure, C18H10I2N2O2, CAS 952145-70-9
3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione
CAS 952145-70-9C18H10I2N2O2
3,6-Bis(4-aminophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione chemical structure, C18H14N4O2, CAS 415709-73-8
3,6-Bis(4-aminophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione
CAS 415709-73-8C18H14N4O2