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Murcko scaffold

Ring system with 4 rings and 22 atoms

25 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 22
Chemicals: 25
With full pages: 1

Scaffold SMILES

O=C1NC(c2ccccc2)=C2C(=O)NC(c3ccccc3)=C12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C1NC(c2ccccc2)=C2C(=O)NC(c3ccccc3)=C12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

2,5-Dimethyl-1,4-dioxo-3,6-diphenylpyrrolo(3,4-c)pyrrole chemical structure, C20H16N2O2, CAS 96159-17-0

2,5-Dimethyl-1,4-dioxo-3,6-diphenylpyrrolo(3,4-c)pyrrole

CAS 96159-17-0C₂₀H₁₆N₂O₂

Pyrrolo[3,4-c]pyrrole-2,5(1H,4H)-dicarboxylic acid, 3,6-bis(4-chlorophenyl)-1,4-dioxo-, 2,5-bis(1,1-dimethylpropyl) ester chemical structure, C30H30Cl2N2O6, CAS 209129-65-7

Pyrrolo[3,4-c]pyrrole-2,5(1H,4H)-dicarboxylic acid, 3,6-bis(4-chlorophenyl)-1,4-dioxo-, 2,5-bis(1,1-dimethylpropyl) ester

CAS 209129-65-7C₃₀H₃₀Cl₂N₂O₆

3,6-Bis(4-bromophenyl)-2,5-dihexyl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione chemical structure, C30H34Br2N2O2, CAS 266357-54-4

3,6-Bis(4-bromophenyl)-2,5-dihexyl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione

CAS 266357-54-4C₃₀H₃₄Br₂N₂O₂

1,4-Diketo-2,5-dimethyl-3,6-di-(4'-chlorophenyl)pyrrolo[3,4-c]pyrrole chemical structure, C20H14Cl2N2O2, CAS 96159-14-7

1,4-Diketo-2,5-dimethyl-3,6-di-(4'-chlorophenyl)pyrrolo[3,4-c]pyrrole

CAS 96159-14-7C₂₀H₁₄Cl₂N₂O₂

1,4-Diketo-2,5-dimethyl-3,6-di-(3'-cyanophenyl)-pyrrolo-[3,4-c]-pyrrole chemical structure, C22H14N4O2, CAS 96158-94-0

1,4-Diketo-2,5-dimethyl-3,6-di-(3'-cyanophenyl)-pyrrolo-[3,4-c]-pyrrole

CAS 96158-94-0C₂₂H₁₄N₄O₂

3,6-Diphenyl-N,N'-dibutylpyrrolo[3,4-c]pyrrole-1,4-dione chemical structure, C26H28N2O2, CAS 96159-01-2

3,6-Diphenyl-N,N'-dibutylpyrrolo[3,4-c]pyrrole-1,4-dione

CAS 96159-01-2C₂₆H₂₈N₂O₂

1,4-Diketo-2,5-di-(carboethoxymethyl)-3,6-diphenylpyrrolo-[3,4-c]-pyrrole chemical structure, C26H24N2O6, CAS 96159-08-9

1,4-Diketo-2,5-di-(carboethoxymethyl)-3,6-diphenylpyrrolo-[3,4-c]-pyrrole

CAS 96159-08-9C₂₆H₂₄N₂O₆

1,4-Diketo-2,5-dibutyl-3,6-di(p-chlorophenyl)pyrrolo[3,4,c]pyrrole chemical structure, C26H26Cl2N2O2, CAS 96159-16-9

1,4-Diketo-2,5-dibutyl-3,6-di(p-chlorophenyl)pyrrolo[3,4,c]pyrrole

CAS 96159-16-9C₂₆H₂₆Cl₂N₂O₂

2,5-Didodecyl-3,6-bis(4-bromophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrol-1,4-dione chemical structure, C42H58Br2N2O2, CAS 852434-98-1

2,5-Didodecyl-3,6-bis(4-bromophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrol-1,4-dione

CAS 852434-98-1C₄₂H₅₈Br₂N₂O₂

3,6-Bis(4-bromophenyl)-2,5-diethyl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione chemical structure, C22H18Br2N2O2, CAS 763522-41-4

3,6-Bis(4-bromophenyl)-2,5-diethyl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione

CAS 763522-41-4C₂₂H₁₈Br₂N₂O₂

3,6-Bis(4-bromophenyl)-2,5-bis(2-ethylhexyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione chemical structure, C34H42Br2N2O2, CAS 852434-82-3

3,6-Bis(4-bromophenyl)-2,5-bis(2-ethylhexyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione

CAS 852434-82-3C₃₄H₄₂Br₂N₂O₂

3,6-Bis(4-bromophenyl)-2,5-dibutyl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione chemical structure, C26H26Br2N2O2, CAS 575451-86-4

3,6-Bis(4-bromophenyl)-2,5-dibutyl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione

CAS 575451-86-4C₂₆H₂₆Br₂N₂O₂

3,6-Bis(4-bromophenyl)-2,5-bis(2-hexyldecyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione chemical structure, C50H74Br2N2O2, CAS 1202519-98-9

3,6-Bis(4-bromophenyl)-2,5-bis(2-hexyldecyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione

CAS 1202519-98-9C₅₀H₇₄Br₂N₂O₂

3,6-Bis(4-bromophenyl)-2,5-dioctyl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione chemical structure, C34H42Br2N2O2, CAS 889573-58-4

3,6-Bis(4-bromophenyl)-2,5-dioctyl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione

CAS 889573-58-4C₃₄H₄₂Br₂N₂O₂

2,2'-(1,4-Dioxo-3,6-diphenylpyrrolo[3,4-c]pyrrole-2,5(1H,4H)-diyl)diacetic acid chemical structure, C22H16N2O6, CAS 632286-84-1

2,2'-(1,4-Dioxo-3,6-diphenylpyrrolo[3,4-c]pyrrole-2,5(1H,4H)-diyl)diacetic acid

CAS 632286-84-1C₂₂H₁₆N₂O₆

2,5-Bis(2-ethylhexyl)-3,6-diphenylpyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione chemical structure, C34H44N2O2, CAS 132029-46-0

2,5-Bis(2-ethylhexyl)-3,6-diphenylpyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione

CAS 132029-46-0C₃₄H₄₄N₂O₂

4,4'-(2,5-Dibutyl-3,6-dioxo-2,3,5,6-tetrahydropyrrolo[3,4-C]pyrrole-1,4-diyl)dibenzaldehyde chemical structure, C28H28N2O4, CAS 1282518-74-4

4,4'-(2,5-Dibutyl-3,6-dioxo-2,3,5,6-tetrahydropyrrolo[3,4-C]pyrrole-1,4-diyl)dibenzaldehyde

CAS 1282518-74-4C₂₈H₂₈N₂O₄

Di-tert-butyl 3,6-bis(4-bromophenyl)-1,4-dioxopyrrolo[3,4-c]pyrrole-2,5(1H,4H)-dicarboxylate chemical structure, C28H26Br2N2O6, CAS 1383674-30-3

Di-tert-butyl 3,6-bis(4-bromophenyl)-1,4-dioxopyrrolo[3,4-c]pyrrole-2,5(1H,4H)-dicarboxylate

CAS 1383674-30-3C₂₈H₂₆Br₂N₂O₆

2,5-Di(2,2-diethoxyethyl)-1,4-diketo-3,6-di(3,4-dimethoxyphenyl)pyrrolo[3,4-c]pyrrole chemical structure, C34H44N2O10, CAS 1375421-30-9

2,5-Di(2,2-diethoxyethyl)-1,4-diketo-3,6-di(3,4-dimethoxyphenyl)pyrrolo[3,4-c]pyrrole

CAS 1375421-30-9C₃₄H₄₄N₂O₁₀

Di-tert-butyl 2,2'-(1,4-dioxo-3,6-diphenylpyrrolo[3,4-c]pyrrole-2,5(1H,4H)-diyl)diacetate chemical structure, C30H32N2O6, CAS 1669409-49-7

Di-tert-butyl 2,2'-(1,4-dioxo-3,6-diphenylpyrrolo[3,4-c]pyrrole-2,5(1H,4H)-diyl)diacetate

CAS 1669409-49-7C₃₀H₃₂N₂O₆

2,5-Dibutyl-3,6-bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione chemical structure, C26H26I2N2O2, CAS 2060531-56-6

2,5-Dibutyl-3,6-bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione

CAS 2060531-56-6C₂₆H₂₆I₂N₂O₂

3,6-Bis(4-methoxyphenyl)-2,5-dimethylpyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione chemical structure, C22H20N2O4, CAS 307303-24-8

3,6-Bis(4-methoxyphenyl)-2,5-dimethylpyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione

CAS 307303-24-8C₂₂H₂₀N₂O₄

2,5-Bis(1,1-dimethylpropyl) 3,6-bis(3-chlorophenyl)-1,4-dioxopyrrolo[3,4-c]pyrrole-2,5(1H,4H)-dicarboxylate chemical structure, C30H30Cl2N2O6, CAS 310897-41-7

2,5-Bis(1,1-dimethylpropyl) 3,6-bis(3-chlorophenyl)-1,4-dioxopyrrolo[3,4-c]pyrrole-2,5(1H,4H)-dicarboxylate

CAS 310897-41-7C₃₀H₃₀Cl₂N₂O₆

2,5-Dihexyl-3,6-bis(4-methoxyphenyl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione chemical structure, C32H40N2O4, CAS 151426-36-7

2,5-Dihexyl-3,6-bis(4-methoxyphenyl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione

CAS 151426-36-7C₃₂H₄₀N₂O₄

2,5-Dihexyl-3,6-bis(4-hydroxyphenyl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione
151426-37-8C₃₀H₃₆N₂O₄