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Murcko scaffold

Ring system with 3 rings and 17 atoms

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
15
With full pages
1
Scaffold SMILES

O=c1ccc2c(cc1)-c1ccccc1CCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccc2c(cc1)-c1ccccc1CCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

Isocolchiceinamide chemical structure, C21H24N2O5, CAS 25269-21-0
Isocolchiceinamide
CAS 25269-21-0C21H24N2O5
Isoethylcolchicine chemical structure, C23H27NO6, CAS 75488-69-6
Isoethylcolchicine
CAS 75488-69-6C23H27NO6
N-Methylisocolchicine chemical structure, C23H27NO6, CAS 7404-91-3
N-Methylisocolchicine
CAS 7404-91-3C23H27NO6
(2R,3R)-2,3-Dihydroxybutanedioic acid--(7S)-7-amino-1,2,3,9-tetramethoxy-6,7-dihydrobenzo[a]heptalen-10(5H)-one (1/1) chemical structure, C24H29NO11, CAS 38838-25-4
(2R,3R)-2,3-Dihydroxybutanedioic acid--(7S)-7-amino-1,2,3,9-tetramethoxy-6,7-dihydrobenzo[a]heptalen-10(5H)-one (1/1)
CAS 38838-25-4C24H29NO11
Benzo(a)heptalen-10(5H)-one, 7-amino-6,7-dihydro-1,2,3,9-tetramethoxy-, (S)- chemical structure, C20H23NO5, CAS 47477-04-3
Benzo(a)heptalen-10(5H)-one, 7-amino-6,7-dihydro-1,2,3,9-tetramethoxy-, (S)-
CAS 47477-04-3C20H23NO5
N-Methylisodemecolcine chemical structure, C22H27NO5, CAS 74483-61-7
N-Methylisodemecolcine
CAS 74483-61-7C22H27NO5
N-Formylisodemecolcine chemical structure, C22H25NO6, CAS 76265-65-1
N-Formylisodemecolcine
CAS 76265-65-1C22H25NO6
Acetamide, 2,2,2-trifluoro-N-(5,6,7,10-tetrahydro-1,2,3,9-tetramethoxy-10-oxobenzo(a)heptalen-7-yl)-, (S)- chemical structure, C22H22F3NO6, CAS 71324-48-6
Acetamide, 2,2,2-trifluoro-N-(5,6,7,10-tetrahydro-1,2,3,9-tetramethoxy-10-oxobenzo(a)heptalen-7-yl)-, (S)-
CAS 71324-48-6C22H22F3NO6
Isocolchicine chemical structure, C22H25NO6, CAS 518-12-7
Isocolchicine
CAS 518-12-7C22H25NO6
Benzo(a)heptalen-10(5H)-one, 7-amino-9-(dimethylamino)-6,7-dihydro-1,2,3-trimethoxy-, (S)- chemical structure, C21H26N2O4, CAS 134595-69-0
Benzo(a)heptalen-10(5H)-one, 7-amino-9-(dimethylamino)-6,7-dihydro-1,2,3-trimethoxy-, (S)-
CAS 134595-69-0C21H26N2O4
2,2,2-Trifluoro-N-(5,6,7,10-tetrahydro-1,2,3,9-tetramethoxy-10-oxobenzo[a]heptalen-7-yl)acetamide chemical structure, C22H22F3NO6, CAS 102491-72-5
2,2,2-Trifluoro-N-(5,6,7,10-tetrahydro-1,2,3,9-tetramethoxy-10-oxobenzo[a]heptalen-7-yl)acetamide
CAS 102491-72-5C22H22F3NO6
(7S)-6,7-Dihydro-1,2,3,9-tetramethoxy-7-(methylamino)benzo(a)heptalen-10(5H)-one chemical structure, C21H25NO5, CAS 4702-33-4
(7S)-6,7-Dihydro-1,2,3,9-tetramethoxy-7-(methylamino)benzo(a)heptalen-10(5H)-one
CAS 4702-33-4C21H25NO5
1,2,3,9-Tetramethoxy-N,N,N-trimethyl-10-oxo-5,6,7,10-tetrahydrobenzo[a]heptalen-7-aminium iodide chemical structure, C23H30INO5, CAS 7596-97-6
1,2,3,9-Tetramethoxy-N,N,N-trimethyl-10-oxo-5,6,7,10-tetrahydrobenzo[a]heptalen-7-aminium iodide
CAS 7596-97-6C23H30INO5
iso-Colchicine-d3 chemical structure, C22H25NO6, CAS 1246818-69-8
iso-Colchicine-d3
CAS 1246818-69-8C22H25NO6
Anticancer agent 40 chemical structure, C25H29NO6, CAS 2760658-33-9
Anticancer agent 40
CAS 2760658-33-9C25H29NO6