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Murcko scaffold

4-(Piperazine-1-sulfonyl)-2,1,3-benzothiadiazole scaffold

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
13
With full pages
3
Scaffold SMILES

O=S(=O)(c1cccc2nsnc12)N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Piperazine-1-sulfonyl)-2,1,3-benzothiadiazole page
Murcko scaffold O=S(=O)(c1cccc2nsnc12)N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

4-Bromo-7-(4-methylpiperazin-1-yl)sulfonyl-2,1,3-benzothiadiazole chemical structure, C11H13BrN4O2S2, CAS 41512-12-3
4-Bromo-7-(4-methylpiperazin-1-yl)sulfonyl-2,1,3-benzothiadiazole
CAS 41512-12-3C11H13BrN4O2S2
4-(4-Methylpiperazin-1-yl)sulfonyl-2,1,3-benzothiadiazole chemical structure, C11H14N4O2S2, CAS 372503-33-8
4-(4-Methylpiperazin-1-yl)sulfonyl-2,1,3-benzothiadiazole
CAS 372503-33-8C11H14N4O2S2
7-Methyl-4-(4-methylpiperazin-1-yl)sulfonyl-2,1,3-benzothiadiazole chemical structure, C12H16N4O2S2, CAS 327981-44-2
7-Methyl-4-(4-methylpiperazin-1-yl)sulfonyl-2,1,3-benzothiadiazole
CAS 327981-44-2C12H16N4O2S2
4-(Piperazine-1-sulfonyl)-2,1,3-benzothiadiazole chemical structure, C10H12N4O2S2, CAS 488122-76-5
4-(Piperazine-1-sulfonyl)-2,1,3-benzothiadiazole
CAS 488122-76-5C10H12N4O2S2
tert-Butyl 4-(2,1,3-benzothiadiazol-4-ylsulfonyl)piperazine-1-carboxylate chemical structure, C15H20N4O4S2, CAS 929836-78-2
tert-Butyl 4-(2,1,3-benzothiadiazol-4-ylsulfonyl)piperazine-1-carboxylate
CAS 929836-78-2C15H20N4O4S2
4-{[4-(Methylsulfonyl)piperazinyl]sulfonyl}benzo[c]1,2,5-thiadiazole chemical structure, C11H14N4O4S3, CAS 669738-55-0
4-{[4-(Methylsulfonyl)piperazinyl]sulfonyl}benzo[c]1,2,5-thiadiazole
CAS 669738-55-0C11H14N4O4S3
4-{[4-(2,2,2-Trifluoroethyl)piperazin-1-yl]sulfonyl}-2,1,3-benzothiadiazole chemical structure, C12H13F3N4O2S2, CAS 1008620-10-7
4-{[4-(2,2,2-Trifluoroethyl)piperazin-1-yl]sulfonyl}-2,1,3-benzothiadiazole
CAS 1008620-10-7C12H13F3N4O2S2
4-[4-(2,1,3-Benzothiadiazol-4-ylsulfonyl)piperazin-1-yl]-4-oxobutanoic acid chemical structure, C14H16N4O5S2, CAS 1081123-99-0
4-[4-(2,1,3-Benzothiadiazol-4-ylsulfonyl)piperazin-1-yl]-4-oxobutanoic acid
CAS 1081123-99-0C14H16N4O5S2
[4-(2,1,3-Benzothiadiazol-4-ylsulfonyl)piperazin-1-yl](oxo)acetic acid chemical structure, C12H12N4O5S2, CAS 1081122-00-0
[4-(2,1,3-Benzothiadiazol-4-ylsulfonyl)piperazin-1-yl](oxo)acetic acid
CAS 1081122-00-0C12H12N4O5S2
4-[4-(2,1,3-Benzothiadiazol-4-ylsulfonyl)piperazin-1-yl]-4-oxo-N-(propan-2-yl)butanamide chemical structure, C17H23N5O4S2, CAS 1081138-97-7
4-[4-(2,1,3-Benzothiadiazol-4-ylsulfonyl)piperazin-1-yl]-4-oxo-N-(propan-2-yl)butanamide
CAS 1081138-97-7C17H23N5O4S2
1-[4-(2,1,3-Benzothiadiazol-4-ylsulfonyl)piperazin-1-yl]-3-methylbutan-1-one chemical structure, C15H20N4O3S2, CAS 1010929-58-4
1-[4-(2,1,3-Benzothiadiazol-4-ylsulfonyl)piperazin-1-yl]-3-methylbutan-1-one
CAS 1010929-58-4C15H20N4O3S2
Ethyl [4-(2,1,3-benzothiadiazol-4-ylsulfonyl)piperazin-1-yl](oxo)acetate chemical structure, C14H16N4O5S2, CAS 1010895-34-7
Ethyl [4-(2,1,3-benzothiadiazol-4-ylsulfonyl)piperazin-1-yl](oxo)acetate
CAS 1010895-34-7C14H16N4O5S2
4-((4-(2-Fluoroethyl)piperazin-1-yl)sulfonyl)benzo[c][1,2,5]thiadiazole chemical structure, C12H15FN4O2S2, CAS 2034534-49-9
4-((4-(2-Fluoroethyl)piperazin-1-yl)sulfonyl)benzo[c][1,2,5]thiadiazole
CAS 2034534-49-9C12H15FN4O2S2