Murcko scaffold
1-(Phenylsulfonyl)pyrrolidine scaffold
843 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 843
- With full pages
- 10
Scaffold SMILES
O=S(=O)(c1ccccc1)N1CCCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 96 of 843 chemicals
![N-[4-(Pyrrolidin-1-ylsulfonyl)phenyl]acetamide chemical structure, C12H16N2O3S, CAS 288154-64-3](/s/FAAZVYRDPYXYPO-UHFFFAOYSA-N.svg)
N-[4-(Pyrrolidin-1-ylsulfonyl)phenyl]acetamide
CAS 288154-64-3C12H16N2O3S
(2S)-1-(Benzenesulfonyl)pyrrolidine-2-carboxylic acid
CAS 88425-46-1C11H13NO4S
(2R)-1-(Benzenesulfonyl)pyrrolidine-2-carboxylic acid
CAS 122213-80-3C11H13NO4S
![1-[(4-Nitrophenyl)sulfonyl]pyrrolidine chemical structure, C10H12N2O4S, CAS 175278-37-2](/s/FFCUNTGOHGZCQO-UHFFFAOYSA-N.svg)
1-[(4-Nitrophenyl)sulfonyl]pyrrolidine
CAS 175278-37-2C10H12N2O4S
1-Tosyl-2-(S)-pyrrolidinemethanol
CAS 55456-48-9C12H17NO3S
1-((3-(Trifluoromethyl)phenyl)sulfonyl)pyrrolidine
CAS 79392-45-3C11H12F3NO2S
![1-[(4-Chlorophenyl)sulfonyl]-D-proline chemical structure, C11H12ClNO4S, CAS 910481-88-8](/s/JXMXHRZHMZMBDK-SNVBAGLBSA-N.svg)
1-[(4-Chlorophenyl)sulfonyl]-D-proline
CAS 910481-88-8C11H12ClNO4S
(E)-3-(3,4-Dimethoxy-5-(pyrrolidin-1-ylsulfonyl)phenyl)acrylic acid
CAS 326882-30-8C15H19NO6S
2-Methoxy-5-(pyrrolidine-1-sulfonyl)-benzoic acid
CAS 89704-51-8C12H15NO5S
1-(4-Bromobenzene-1-sulfonyl)pyrrolidine
CAS 136350-52-2C10H12BrNO2S
1-(2,5-Dimethoxyphenyl)sulfonylpyrrolidine
CAS 797765-53-8C12H17NO4S
1-(2-Nitrophenylsulfonyl)pyrrolidine
CAS 327069-81-8C10H12N2O4S
4-Methoxy-3-(pyrrolidine-1-sulfonyl)benzoic acid
CAS 299181-37-6C12H15NO5S
4-(Pyrrolidine-1-sulfonyl)benzoic acid
CAS 19580-33-7C11H13NO4S
1-((3-Bromo-4-methoxyphenyl)sulfonyl)pyrrolidine
CAS 332354-62-8C11H14BrNO3S
Methyl 2,4-dichloro-5-(pyrrolidin-1-ylsulfonyl)benzoate
CAS 351336-07-7C12H13Cl2NO4S
3-(Pyrrolidine-1-sulfonyl)benzoic acid
CAS 7326-79-6C11H13NO4S
![1-[(2,5-Dichlorophenyl)sulfonyl]pyrrolidine chemical structure, C10H11Cl2NO2S, CAS 326898-65-1](/s/JVEVLWSAAUWYPE-UHFFFAOYSA-N.svg)
1-[(2,5-Dichlorophenyl)sulfonyl]pyrrolidine
CAS 326898-65-1C10H11Cl2NO2S
2-Methoxy-N-(4-pyrrolidin-1-ylsulfonylphenyl)acetamide
CAS 510737-09-4C13H18N2O4S
1-(3,4-Dimethoxyphenyl)sulfonylpyrrolidine
CAS 226544-96-3C12H17NO4S
![(2E)-3-[4-Methoxy-3-(pyrrolidin-1-ylsulfonyl)phenyl]acrylic acid chemical structure, C14H17NO5S, CAS 324779-72-8](/s/YYPLTSZGZCLXHC-FNORWQNLSA-N.svg)
(2E)-3-[4-Methoxy-3-(pyrrolidin-1-ylsulfonyl)phenyl]acrylic acid
CAS 324779-72-8C14H17NO5S
1-(4-(Pyrrolidin-1-ylsulfonyl)phenyl)ethanone
CAS 58722-33-1C12H15NO3S
4-(Pyrrolidin-1-ylsulfonyl)benzenesulfonamide
CAS 424813-23-0C10H14N2O4S2
1-(4-Chloro-benzenesulfonyl)-pyrrolidine
CAS 74832-69-2C10H12ClNO2S
- 2-Bromo-5-(pyrrolidin-1-ylsulfonyl)benzoic acid22361-65-5C11H12BrNO4S
- 2 suppliers1-(4-Fluorobenzenesulfonyl)pyrrolidine157187-14-9C10H12FNO2S
- 2,2,2-Trifluoro-N-[4-(1-pyrrolidinylsulfonyl)phenyl]acetamide327066-50-2C12H13F3N2O3S
- Methyl 4-oxo-4-(4-pyrrolidin-1-ylsulfonylanilino)butanoate327067-58-3C15H20N2O5S
- 4-Oxo-4-[4-(pyrrolidin-1-ylsulfonyl)anilino]butanoic acid349626-89-7C14H18N2O5S
- N-(4-Pyrrolidin-1-ylsulfonylphenyl)propanamide315672-44-7C13H18N2O3S
- N-(4-Pyrrolidin-1-ylsulfonylphenyl)butanamide355436-97-4C14H20N2O3S
- 1-(2,3-Dichloro-4-methoxyphenyl)sulfonylpyrrolidine667877-91-0C11H13Cl2NO3S
- 1-(4-Methoxy-2,5-dimethylphenyl)sulfonylpyrrolidine667892-59-3C13H19NO3S
- [(5-Methoxy-2,4-dimethylphenyl)sulfonyl]pyrrolidine723742-59-4C13H19NO3S
- 1-(4-Chloro-3-ethoxyphenyl)sulfonylpyrrolidine706773-90-2C12H16ClNO3S
- 1-(4-Ethoxy-2,5-dimethylphenyl)sulfonylpyrrolidine701942-56-5C14H21NO3S
- 1-(4-Methoxy-3-propan-2-ylphenyl)sulfonylpyrrolidine701282-68-0C14H21NO3S
- 1-(5-Chloro-2-methoxy-4-methylbenzenesulfonyl)pyrrolidine706775-34-0C12H16ClNO3S
- 1-(5-Chloro-2-ethoxy-4-methylbenzenesulfonyl)pyrrolidine717863-63-3C13H18ClNO3S
- 1-(2-Ethoxy-4-methyl-5-propan-2-ylphenyl)sulfonylpyrrolidine723744-11-4C16H25NO3S
- 1-(4-Bromo-2-ethoxyphenyl)sulfonylpyrrolidine723744-14-7C12H16BrNO3S
- 1-(2,5-Dichloro-4-ethoxyphenyl)sulfonylpyrrolidine723745-29-7C12H15Cl2NO3S
- 2-(4-Chloro-2-methyl-5-pyrrolidin-1-ylsulfonylphenoxy)acetamide701221-38-7C13H17ClN2O4S
- 4-Methyl-3-(1-pyrrolidinylsulfonyl)benzoic acid517881-18-4C12H15NO4S
- Methyl 4-(pyrrolidin-1-ylsulfonyl)benzoate333787-82-9C12H15NO4S
- 1-((4-Iodophenyl)sulfonyl)pyrrolidine167156-16-3C10H12INO2S
- (E)-3-(4-Methyl-3-(pyrrolidin-1-ylsulfonyl)phenyl)acrylic acid327094-05-3C14H17NO4S
- 1-(3-Methoxyphenyl)sulfonylpyrrolidine670272-01-2C11H15NO3S
Related scaffolds
Same ring framework with different atoms or bond orders
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c1ccc(CN2CCCC2)cc113 chemicals![Scaffold c1ncc(C[n+]2ccsc2)cn1](/scaffold/VOZNMBMJVMRVOB-UHFFFAOYSA-N/structure.svg)
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c1ccc(Cc2cnc[nH]2)cc19 chemicals
O=C1NC(=S)SC1=Cc1ccccc19 chemicals
O=C(c1ccccc1)c1cccs18 chemicals
O=C1CCCN1Cc1ccccc18 chemicals
c1ccc(CC2CCCC2)cc18 chemicals![Scaffold O=C(c1ccccc1)c1ccc[nH]1](/scaffold/NFGGQMYSOLVBLF-UHFFFAOYSA-N/structure.svg)
O=C(c1ccccc1)c1ccc[nH]17 chemicals