Murcko scaffold
1-Benzyl-3-pyrrolidone scaffold
636 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 13
- Chemicals
- 636
- With full pages
- 53
Scaffold SMILES
O=C1CCCN1Cc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 636 chemicals
Nebracetam
CAS 97205-34-0C12H16N2O
1-Benzyl-3-pyrrolidone
CAS 5291-77-0C11H13NO
Methyl 1-benzyl-5-oxopyrrolidine-3-carboxylate
CAS 51535-00-3C13H15NO3
1-Benzyl-5-oxo-pyrrolidine-3-carboxylic acid
CAS 5733-86-8C12H13NO3
4-Chlorobenzyl-2-pyrrolidone-5-carboxylate
CAS 124277-34-5C12H11ClNO3-
![1-[(4-Chlorophenyl)methyl]-5-oxopyrrolidine-2-carboxylic acid chemical structure, C12H12ClNO3, CAS 116404-24-1](/s/BCZYCMUPDFSLAA-UHFFFAOYSA-N.svg)
1-[(4-Chlorophenyl)methyl]-5-oxopyrrolidine-2-carboxylic acid
CAS 116404-24-1C12H12ClNO3
1-Benzyl-4-(hydroxymethyl)pyrrolidin-2-one
CAS 96449-69-3C12H15NO2
1-Benzyl-3-hydroxypyrrolidin-2-one
CAS 5336-34-5C11H13NO2
1-Benzyl-5-oxopyrrolidine-2-carboxylic acid
CAS 78964-11-1C12H13NO3
1-Benzyl-5-(hydroxymethyl)pyrrolidin-2-one
CAS 116041-30-6C12H15NO2
Ethyl 1-benzyl-5-oxopyrrolidine-2-carboxylate
CAS 942603-46-5C14H17NO3
1-(2-Methoxybenzyl)-5-oxopyrrolidine-3-carboxylic acid
CAS 352208-42-5C13H15NO4
5-Oxo-1-(1-phenylethyl)-3-pyrrolidinecarboxylic acid
CAS 96449-93-3C13H15NO3
(S)-1-Benzyl-5-oxo-pyrrolidine-3-carboxylic acid methyl ester
CAS 428518-44-9C13H15NO3
Methyl (3R)-1-benzyl-5-oxopyrrolidine-3-carboxylate
CAS 428518-36-9C13H15NO3
![(3S)-5-Oxo-1-[(1S)-1-phenylethyl]pyrrolidine-3-carboxylic acid chemical structure, C13H15NO3, CAS 173340-19-7](/s/CFGKWSDAMXTRHE-ONGXEEELSA-N.svg)
(3S)-5-Oxo-1-[(1S)-1-phenylethyl]pyrrolidine-3-carboxylic acid
CAS 173340-19-7C13H15NO3
(3S)-5-Oxo-1-((1R)-1-phenylethyl)pyrrolidine-3-carboxylic acid
CAS 99735-44-1C13H15NO3
![(3R)-5-Oxo-1-[(1S)-1-phenylethyl]pyrrolidine-3-carboxylic acid chemical structure, C13H15NO3, CAS 146348-15-4](/s/CFGKWSDAMXTRHE-GXSJLCMTSA-N.svg)
(3R)-5-Oxo-1-[(1S)-1-phenylethyl]pyrrolidine-3-carboxylic acid
CAS 146348-15-4C13H15NO3
(3R)-5-Oxo-1-((1R)-1-phenylethyl)pyrrolidine-3-carboxylic acid
CAS 99735-43-0C13H15NO3
(S)-1-Benzyl-5-oxopyrrolidine-3-carboxylic acid
CAS 428518-42-7C12H13NO3
(R)-1-Benzyl-5-oxopyrrolidine-3-carboxylic acid
CAS 1217736-39-4C12H13NO3
1-(2-Methoxy-5-nitrobenzyl)pyrrolidin-2-one hydrochloride
CAS 696640-58-1C12H14N2O4
1-(2-Chlorobenzyl)-5-oxopyrrolidine-3-carboxylic acid
CAS 175205-45-5C12H12ClNO3
1-(4-Chlorobenzyl)-5-oxopyrrolidine-3-carboxylic acid
CAS 96449-92-2C12H12ClNO3
- 5-Oxo-1-[4-(trifluoromethyl)benzyl]pyrrolidine-3-carboxylic acid253178-82-4C13H12F3NO3
- 3 suppliers1-((4-Methylphenyl)methyl)-5-oxopyrrolidine-3-carboxylic acid96449-91-1C13H15NO3
- 1-Benzyl-5-oxo-3-pyrrolidinecarbohydrazide368429-72-5C12H15N3O2
- 2 suppliers1-(4-Fluorobenzyl)-5-oxopyrrolidine-3-carboxylic acid96449-68-2C12H12FNO3
- 1-(4-Methoxybenzyl)-5-oxopyrrolidine-3-carboxylic acid96449-89-7C13H15NO4
- 1-(4-Ethylbenzyl)-5-oxopyrrolidine-3-carboxylic acid824981-40-0C14H17NO3
- L-Proline, 1-((4-fluorophenyl)methyl)-5-oxo-, methyl ester59749-17-6C13H14FNO3
- L-Proline, 1-((4-chlorophenyl)methyl)-5-oxo-, methyl ester59749-18-7C13H14ClNO3
- L-Proline, 1-((3,4-dichlorophenyl)methyl)-5-oxo-, methyl ester59749-19-8C13H13Cl2NO3
- L-Proline, 1-((2,6-dichlorophenyl)methyl)-5-oxo-, methyl ester59749-20-1C13H13Cl2NO3
- L-Proline, 1-((4-fluorophenyl)methyl)-5-oxo-59749-21-2C12H12FNO3
- L-Proline, 1-((4-chlorophenyl)methyl)-5-oxo-59749-22-3C12H12ClNO3
- L-Proline, 1-((3,4-dichlorophenyl)methyl)-5-oxo-59749-23-4C12H11Cl2NO3
- L-Proline, 1-((2,4-dichlorophenyl)methyl)-5-oxo-59749-24-5C12H11Cl2NO3
- L-Proline, 1-((4-fluorophenyl)methyl)-5-oxo-, ammonium salt59749-27-8C12H15FN2O3
- L-Proline, 1-((4-chlorophenyl)methyl)-5-oxo-, ammonium salt59749-28-9C12H15ClN2O3
- L-Proline, 1-((4-fluorophenyl)methyl)-5-oxo-, compd. with N-(1-methylethyl)benzenemethanamine (1:1)59749-29-0C22H27FN2O3
- L-Proline, 1-((4-fluorophenyl)methyl)-5-oxo-, compd. with N-(1-methylethyl)-2-propanamine (1:1)59749-30-3C18H27FN2O3
- L-Proline, 1-((4-fluorophenyl)methyl)-5-oxo-, compd. with N-ethylethanamine (1:1)59749-31-4C16H23FN2O3
- L-Proline, 1-((4-chlorophenyl)methyl)-5-oxo-, compd. with N-ethylethanamine (1:1)59749-32-5C16H23ClN2O3
- L-Proline, 1-((4-chlorophenyl)methyl)-5-oxo-, compd. with N-(1-methylethyl)-2-propanamine (1:1)59749-33-6C18H27ClN2O3
- L-Proline, 1-((4-chlorophenyl)methyl)-5-oxo-, compd. with N-(1-methylethyl)benzenemethanamine (1:1)59749-34-7C22H27ClN2O3
- L-Proline, 1-((3,4-dichlorophenyl)methyl)-5-oxo-, compd. with 2-propanamine (1:1)59749-35-8C15H20Cl2N2O3
- 1-Benzyl-5-ethoxypyrrolidin-2-one108634-46-4C13H17NO2
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