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Murcko scaffold

Ring system with 2 rings and 19 atoms

28 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
28
With full pages
13
Scaffold SMILES

O=C(CCS(=O)(=O)c1ccccc1)Nc1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCS(=O)(=O)c1ccccc1)Nc1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

2-[3-(4-Chlorobenzenesulfonyl)propanamido]thiophene-3-carboxamide chemical structure, C14H13ClN2O4S2, CAS 851174-34-0
2-[3-(4-Chlorobenzenesulfonyl)propanamido]thiophene-3-carboxamide
CAS 851174-34-0C14H13ClN2O4S2
2-[3-(4-Methylbenzenesulfonyl)propanamido]thiophene-3-carboxamide chemical structure, C15H16N2O4S2, CAS 848582-90-1
2-[3-(4-Methylbenzenesulfonyl)propanamido]thiophene-3-carboxamide
CAS 848582-90-1C15H16N2O4S2
3-(Benzenesulfonyl)-N-(3-cyanothiophen-2-yl)propanamide chemical structure, C14H12N2O3S2, CAS 868676-99-7
3-(Benzenesulfonyl)-N-(3-cyanothiophen-2-yl)propanamide
CAS 868676-99-7C14H12N2O3S2
2-(3-(Phenylsulfonyl)propanamido)thiophene-3-carboxamide chemical structure, C14H14N2O4S2, CAS 868677-05-8
2-(3-(Phenylsulfonyl)propanamido)thiophene-3-carboxamide
CAS 868677-05-8C14H14N2O4S2
N-Methyl-2-(3-(phenylsulfonyl)propanamido)thiophene-3-carboxamide chemical structure, C15H16N2O4S2, CAS 868677-07-0
N-Methyl-2-(3-(phenylsulfonyl)propanamido)thiophene-3-carboxamide
CAS 868677-07-0C15H16N2O4S2
Methyl 2-(3-(phenylsulfonyl)propanamido)thiophene-3-carboxylate chemical structure, C15H15NO5S2, CAS 892842-16-9
Methyl 2-(3-(phenylsulfonyl)propanamido)thiophene-3-carboxylate
CAS 892842-16-9C15H15NO5S2
Ethyl 2-(3-(phenylsulfonyl)propanamido)thiophene-3-carboxylate chemical structure, C16H17NO5S2, CAS 892842-28-3
Ethyl 2-(3-(phenylsulfonyl)propanamido)thiophene-3-carboxylate
CAS 892842-28-3C16H17NO5S2
2-[3-(4-Chlorophenyl)sulfonylpropanoylamino]-N-methylthiophene-3-carboxamide chemical structure, C15H15ClN2O4S2, CAS 895466-32-7
2-[3-(4-Chlorophenyl)sulfonylpropanoylamino]-N-methylthiophene-3-carboxamide
CAS 895466-32-7C15H15ClN2O4S2
2-[3-(4-Fluorophenyl)sulfonylpropanoylamino]thiophene-3-carboxamide chemical structure, C14H13FN2O4S2, CAS 895450-98-3
2-[3-(4-Fluorophenyl)sulfonylpropanoylamino]thiophene-3-carboxamide
CAS 895450-98-3C14H13FN2O4S2
2-[3-(4-Fluorophenyl)sulfonylpropanoylamino]-N-methylthiophene-3-carboxamide chemical structure, C15H15FN2O4S2, CAS 895451-05-5
2-[3-(4-Fluorophenyl)sulfonylpropanoylamino]-N-methylthiophene-3-carboxamide
CAS 895451-05-5C15H15FN2O4S2
3-(Benzenesulfonyl)-N-(3-cyano-4,5-dimethylthiophen-2-yl)propanamide chemical structure, C16H16N2O3S2, CAS 896305-82-1
3-(Benzenesulfonyl)-N-(3-cyano-4,5-dimethylthiophen-2-yl)propanamide
CAS 896305-82-1C16H16N2O3S2
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-3-(4-fluorophenyl)sulfonylpropanamide chemical structure, C16H15FN2O3S2, CAS 896306-20-0
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-3-(4-fluorophenyl)sulfonylpropanamide
CAS 896306-20-0C16H15FN2O3S2
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-3-tosylpropanamide chemical structure, C17H18N2O3S2, CAS 896306-52-8
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-3-tosylpropanamide
CAS 896306-52-8C17H18N2O3S2
3-(4-Chlorophenyl)sulfonyl-N-(3-cyano-4,5-dimethylthiophen-2-yl)propanamide chemical structure, C16H15ClN2O3S2, CAS 896306-82-4
3-(4-Chlorophenyl)sulfonyl-N-(3-cyano-4,5-dimethylthiophen-2-yl)propanamide
CAS 896306-82-4C16H15ClN2O3S2
2-[3-(4-Chlorophenyl)sulfonylpropanoylamino]-4,5-dimethylthiophene-3-carboxamide chemical structure, C16H17ClN2O4S2, CAS 896292-04-9
2-[3-(4-Chlorophenyl)sulfonylpropanoylamino]-4,5-dimethylthiophene-3-carboxamide
CAS 896292-04-9C16H17ClN2O4S2
2-[3-(4-Fluorophenyl)sulfonylpropanoylamino]-N,4,5-trimethylthiophene-3-carboxamide chemical structure, C17H19FN2O4S2, CAS 896301-34-1
2-[3-(4-Fluorophenyl)sulfonylpropanoylamino]-N,4,5-trimethylthiophene-3-carboxamide
CAS 896301-34-1C17H19FN2O4S2
N,4,5-trimethyl-2-(3-tosylpropanamido)thiophene-3-carboxamide chemical structure, C18H22N2O4S2, CAS 896301-65-8
N,4,5-trimethyl-2-(3-tosylpropanamido)thiophene-3-carboxamide
CAS 896301-65-8C18H22N2O4S2
Methyl 2-[3-(4-fluorophenyl)sulfonylpropanoylamino]-4,5-dimethylthiophene-3-carboxylate chemical structure, C17H18FNO5S2, CAS 896616-70-9
Methyl 2-[3-(4-fluorophenyl)sulfonylpropanoylamino]-4,5-dimethylthiophene-3-carboxylate
CAS 896616-70-9C17H18FNO5S2
2-[3-(4-Fluorophenyl)sulfonylpropanoylamino]-4,5-dimethylthiophene-3-carboxamide chemical structure, C16H17FN2O4S2, CAS 896291-32-0
2-[3-(4-Fluorophenyl)sulfonylpropanoylamino]-4,5-dimethylthiophene-3-carboxamide
CAS 896291-32-0C16H17FN2O4S2
Methyl 2-[3-(4-chlorophenyl)sulfonylpropanoylamino]-4,5-dimethylthiophene-3-carboxylate chemical structure, C17H18ClNO5S2, CAS 896616-96-9
Methyl 2-[3-(4-chlorophenyl)sulfonylpropanoylamino]-4,5-dimethylthiophene-3-carboxylate
CAS 896616-96-9C17H18ClNO5S2
Ethyl 5-[3-(4-chlorophenyl)sulfonylpropanoylamino]-3-methylthiophene-2-carboxylate chemical structure, C17H18ClNO5S2, CAS 895462-10-9
Ethyl 5-[3-(4-chlorophenyl)sulfonylpropanoylamino]-3-methylthiophene-2-carboxylate
CAS 895462-10-9C17H18ClNO5S2
Methyl 2-[3-(4-chlorophenyl)sulfonylpropanoylamino]thiophene-3-carboxylate chemical structure, C15H14ClNO5S2, CAS 895466-11-2
Methyl 2-[3-(4-chlorophenyl)sulfonylpropanoylamino]thiophene-3-carboxylate
CAS 895466-11-2C15H14ClNO5S2
N-Methyl-2-(3-tosylpropanamido)thiophene-3-carboxamide chemical structure, C16H18N2O4S2, CAS 895451-71-5
N-Methyl-2-(3-tosylpropanamido)thiophene-3-carboxamide
CAS 895451-71-5C16H18N2O4S2
N,4,5-trimethyl-2-(3-(phenylsulfonyl)propanamido)thiophene-3-carboxamide chemical structure, C17H20N2O4S2, CAS 896300-89-3
N,4,5-trimethyl-2-(3-(phenylsulfonyl)propanamido)thiophene-3-carboxamide
CAS 896300-89-3C17H20N2O4S2