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Murcko scaffold

Ring system with 2 rings and 18 atoms

34 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
34
With full pages
11
Scaffold SMILES

O=C(NNC(=S)Nc1ccccc1)c1cc[nH]n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NNC(=S)Nc1ccccc1)c1cc[nH]n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 34 of 34 chemicals

2-[(3-Methyl-1H-pyrazol-5-yl)carbonyl]-N-phenylhydrazinecarbothioamide chemical structure, C12H13N5OS, CAS 944779-31-1
2-[(3-Methyl-1H-pyrazol-5-yl)carbonyl]-N-phenylhydrazinecarbothioamide
CAS 944779-31-1C12H13N5OS
1-[(2,5-Dimethylpyrazole-3-carbonyl)amino]-3-(2-methoxyphenyl)thiourea chemical structure, C14H17N5O2S, CAS 512808-59-2
1-[(2,5-Dimethylpyrazole-3-carbonyl)amino]-3-(2-methoxyphenyl)thiourea
CAS 512808-59-2C14H17N5O2S
1-[[(1,5-Dimethyl-3-pyrazolyl)-oxomethyl]amino]-3-(2-methoxyphenyl)thiourea chemical structure, C14H17N5O2S, CAS 512808-35-4
1-[[(1,5-Dimethyl-3-pyrazolyl)-oxomethyl]amino]-3-(2-methoxyphenyl)thiourea
CAS 512808-35-4C14H17N5O2S
2-[(4-Chloro-1,5-dimethyl-1H-pyrazol-3-yl)carbonyl]-N-(4-fluorophenyl)hydrazinecarbothioamide chemical structure, C13H13ClFN5OS, CAS 512808-28-5
2-[(4-Chloro-1,5-dimethyl-1H-pyrazol-3-yl)carbonyl]-N-(4-fluorophenyl)hydrazinecarbothioamide
CAS 512808-28-5C13H13ClFN5OS
1-[(1,5-Dimethylpyrazole-3-carbonyl)amino]-3-(4-methylphenyl)thiourea chemical structure, C14H17N5OS, CAS 512808-91-2
1-[(1,5-Dimethylpyrazole-3-carbonyl)amino]-3-(4-methylphenyl)thiourea
CAS 512808-91-2C14H17N5OS
1-[(4-Chloro-2,5-dimethylpyrazole-3-carbonyl)amino]-3-(4-methylphenyl)thiourea chemical structure, C14H16ClN5OS, CAS 512808-73-0
1-[(4-Chloro-2,5-dimethylpyrazole-3-carbonyl)amino]-3-(4-methylphenyl)thiourea
CAS 512808-73-0C14H16ClN5OS
1-[(2,5-Dimethylpyrazole-3-carbonyl)amino]-3-(4-ethoxyphenyl)thiourea chemical structure, C15H19N5O2S, CAS 512808-75-2
1-[(2,5-Dimethylpyrazole-3-carbonyl)amino]-3-(4-ethoxyphenyl)thiourea
CAS 512808-75-2C15H19N5O2S
1-[(4-Chloro-1,5-dimethylpyrazole-3-carbonyl)amino]-3-(4-methylphenyl)thiourea chemical structure, C14H16ClN5OS, CAS 512808-77-4
1-[(4-Chloro-1,5-dimethylpyrazole-3-carbonyl)amino]-3-(4-methylphenyl)thiourea
CAS 512808-77-4C14H16ClN5OS
1-[(1,5-Dimethylpyrazole-3-carbonyl)amino]-3-(4-ethoxyphenyl)thiourea chemical structure, C15H19N5O2S, CAS 512808-97-8
1-[(1,5-Dimethylpyrazole-3-carbonyl)amino]-3-(4-ethoxyphenyl)thiourea
CAS 512808-97-8C15H19N5O2S
2-[(4-Chloro-1-methyl-1H-pyrazol-3-yl)carbonyl]-N-(3-chlorophenyl)hydrazinecarbothioamide chemical structure, C12H11Cl2N5OS, CAS 512810-35-4
2-[(4-Chloro-1-methyl-1H-pyrazol-3-yl)carbonyl]-N-(3-chlorophenyl)hydrazinecarbothioamide
CAS 512810-35-4C12H11Cl2N5OS
2-[(4-Chloro-1-methyl-1H-pyrazol-3-yl)carbonyl]-N-(4-methylphenyl)hydrazinecarbothioamide chemical structure, C13H14ClN5OS, CAS 512810-64-9
2-[(4-Chloro-1-methyl-1H-pyrazol-3-yl)carbonyl]-N-(4-methylphenyl)hydrazinecarbothioamide
CAS 512810-64-9C13H14ClN5OS
2-[(4-Chloro-1-methyl-1H-pyrazol-3-yl)carbonyl]-N-(2-methoxyphenyl)hydrazinecarbothioamide chemical structure, C13H14ClN5O2S, CAS 512811-22-2
2-[(4-Chloro-1-methyl-1H-pyrazol-3-yl)carbonyl]-N-(2-methoxyphenyl)hydrazinecarbothioamide
CAS 512811-22-2C13H14ClN5O2S
1-[(4-Chloro-1-methylpyrazole-3-carbonyl)amino]-3-(4-fluorophenyl)thiourea chemical structure, C12H11ClFN5OS, CAS 512811-37-9
1-[(4-Chloro-1-methylpyrazole-3-carbonyl)amino]-3-(4-fluorophenyl)thiourea
CAS 512811-37-9C12H11ClFN5OS
2-[(4-Chloro-1,5-dimethyl-1H-pyrazol-3-yl)carbonyl]-N-phenylhydrazinecarbothioamide chemical structure, C13H14ClN5OS, CAS 512812-24-7
2-[(4-Chloro-1,5-dimethyl-1H-pyrazol-3-yl)carbonyl]-N-phenylhydrazinecarbothioamide
CAS 512812-24-7C13H14ClN5OS
1-[(4-Chloro-1-methylpyrazole-3-carbonyl)amino]-3-phenylthiourea chemical structure, C12H12ClN5OS, CAS 512812-95-2
1-[(4-Chloro-1-methylpyrazole-3-carbonyl)amino]-3-phenylthiourea
CAS 512812-95-2C12H12ClN5OS
1-[(4-Bromo-1,5-dimethylpyrazole-3-carbonyl)amino]-3-(4-fluorophenyl)thiourea chemical structure, C13H13BrFN5OS, CAS 512808-64-9
1-[(4-Bromo-1,5-dimethylpyrazole-3-carbonyl)amino]-3-(4-fluorophenyl)thiourea
CAS 512808-64-9C13H13BrFN5OS
1-[(4-Chloro-2,5-dimethylpyrazole-3-carbonyl)amino]-3-(4-ethoxyphenyl)thiourea chemical structure, C15H18ClN5O2S, CAS 512808-95-6
1-[(4-Chloro-2,5-dimethylpyrazole-3-carbonyl)amino]-3-(4-ethoxyphenyl)thiourea
CAS 512808-95-6C15H18ClN5O2S
1-[(4-Chloro-1,5-dimethylpyrazole-3-carbonyl)amino]-3-(4-ethoxyphenyl)thiourea chemical structure, C15H18ClN5O2S, CAS 512808-84-3
1-[(4-Chloro-1,5-dimethylpyrazole-3-carbonyl)amino]-3-(4-ethoxyphenyl)thiourea
CAS 512808-84-3C15H18ClN5O2S
1-[(4-Bromo-1,5-dimethylpyrazole-3-carbonyl)amino]-3-(4-ethoxyphenyl)thiourea chemical structure, C15H18BrN5O2S, CAS 512808-71-8
1-[(4-Bromo-1,5-dimethylpyrazole-3-carbonyl)amino]-3-(4-ethoxyphenyl)thiourea
CAS 512808-71-8C15H18BrN5O2S
2-[(4-Chloro-1,3-dimethyl-1H-pyrazol-5-yl)carbonyl]-N-(2-methoxyphenyl)hydrazinecarbothioamide chemical structure, C14H16ClN5O2S, CAS 512808-98-9
2-[(4-Chloro-1,3-dimethyl-1H-pyrazol-5-yl)carbonyl]-N-(2-methoxyphenyl)hydrazinecarbothioamide
CAS 512808-98-9C14H16ClN5O2S
1-[(4-Chloro-1-methylpyrazole-3-carbonyl)amino]-3-(4-ethoxyphenyl)thiourea chemical structure, C14H16ClN5O2S, CAS 512811-04-0
1-[(4-Chloro-1-methylpyrazole-3-carbonyl)amino]-3-(4-ethoxyphenyl)thiourea
CAS 512811-04-0C14H16ClN5O2S
1-(3-Chlorophenyl)-3-[[2-methyl-5-(trifluoromethyl)pyrazole-3-carbonyl]amino]thiourea chemical structure, C13H11ClF3N5OS, CAS 512823-67-5
1-(3-Chlorophenyl)-3-[[2-methyl-5-(trifluoromethyl)pyrazole-3-carbonyl]amino]thiourea
CAS 512823-67-5C13H11ClF3N5OS
Ethyl 4-[({[(4-bromo-1,3-dimethylpyrazol-5-yl)carbonylamino]amino}thioxomethyl)amino]benzoate chemical structure, C16H18BrN5O3S, CAS 902662-34-4
Ethyl 4-[({[(4-bromo-1,3-dimethylpyrazol-5-yl)carbonylamino]amino}thioxomethyl)amino]benzoate
CAS 902662-34-4C16H18BrN5O3S
Ethyl 4-[({2-[(4-iodo-1-methyl-1H-pyrazol-3-yl)carbonyl]hydrazinyl}carbonothioyl)amino]benzoate chemical structure, C15H16IN5O3S, CAS 902704-95-4
Ethyl 4-[({2-[(4-iodo-1-methyl-1H-pyrazol-3-yl)carbonyl]hydrazinyl}carbonothioyl)amino]benzoate
CAS 902704-95-4C15H16IN5O3S