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Murcko scaffold

Ring system with 2 rings and 17 atoms

24 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
24
With full pages
12
Scaffold SMILES

O=C(Cc1ccc[nH]1)NN=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccc[nH]1)NN=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

2-(1-Methyl-1H-pyrrol-2-yl)-N'-{(E)-[4-(methylsulfanyl)phenyl]methylidene}acetohydrazide chemical structure, C15H17N3OS, CAS 307509-82-6
2-(1-Methyl-1H-pyrrol-2-yl)-N'-{(E)-[4-(methylsulfanyl)phenyl]methylidene}acetohydrazide
CAS 307509-82-6C15H17N3OS
N'-(4-Ethylbenzylidene)-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide chemical structure, C16H19N3O, CAS 314069-20-0
N'-(4-Ethylbenzylidene)-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide
CAS 314069-20-0C16H19N3O
N-[(1Z)-2-(2-Chloro-6-fluorophenyl)-1-azavinyl]-2-(1-methylpyrrol-2-yl)acetami de chemical structure, C14H13ClFN3O, CAS 314070-87-6
N-[(1Z)-2-(2-Chloro-6-fluorophenyl)-1-azavinyl]-2-(1-methylpyrrol-2-yl)acetami de
CAS 314070-87-6C14H13ClFN3O
N'-(2,3-Dichlorobenzylidene)-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide chemical structure, C14H13Cl2N3O, CAS 314070-88-7
N'-(2,3-Dichlorobenzylidene)-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide
CAS 314070-88-7C14H13Cl2N3O
2-(1-Methyl-1H-pyrrol-2-yl)-N'-(3,4,5-trimethoxybenzylidene)acetohydrazide chemical structure, C17H21N3O4, CAS 314070-93-4
2-(1-Methyl-1H-pyrrol-2-yl)-N'-(3,4,5-trimethoxybenzylidene)acetohydrazide
CAS 314070-93-4C17H21N3O4
N'-(3,4-Dichlorobenzylidene)-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide chemical structure, C14H13Cl2N3O, CAS 314070-96-7
N'-(3,4-Dichlorobenzylidene)-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide
CAS 314070-96-7C14H13Cl2N3O
2-(1-Methyl-1H-pyrrol-2-yl)-N'-(2,3,4-trimethoxybenzylidene)acetohydrazide chemical structure, C17H21N3O4, CAS 314070-98-9
2-(1-Methyl-1H-pyrrol-2-yl)-N'-(2,3,4-trimethoxybenzylidene)acetohydrazide
CAS 314070-98-9C17H21N3O4
2-(1-Methyl-1H-pyrrol-2-yl)-N'-(2,4,5-trimethoxybenzylidene)acetohydrazide chemical structure, C17H21N3O4, CAS 314070-99-0
2-(1-Methyl-1H-pyrrol-2-yl)-N'-(2,4,5-trimethoxybenzylidene)acetohydrazide
CAS 314070-99-0C17H21N3O4
N'-(4-Bromobenzylidene)-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide chemical structure, C14H14BrN3O, CAS 314071-12-0
N'-(4-Bromobenzylidene)-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide
CAS 314071-12-0C14H14BrN3O
N'-(1-(4-Chlorophenyl)ethylidene)-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide chemical structure, C15H16ClN3O, CAS 314071-31-3
N'-(1-(4-Chlorophenyl)ethylidene)-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide
CAS 314071-31-3C15H16ClN3O
N-[(E)-(4-tert-Butylphenyl)methylideneamino]-2-(1-methylpyrrol-2-yl)acetamide chemical structure, C18H23N3O, CAS 314070-95-6
N-[(E)-(4-tert-Butylphenyl)methylideneamino]-2-(1-methylpyrrol-2-yl)acetamide
CAS 314070-95-6C18H23N3O
N-[(E)-(4-Methylphenyl)methylideneamino]-2-(1-methylpyrrol-2-yl)acetamide chemical structure, C15H17N3O, CAS 314071-16-4
N-[(E)-(4-Methylphenyl)methylideneamino]-2-(1-methylpyrrol-2-yl)acetamide
CAS 314071-16-4C15H17N3O
N'-[(E)-(4-Chloro-3-nitrophenyl)methylidene]-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide chemical structure, C14H13ClN4O3, CAS 315226-28-9
N'-[(E)-(4-Chloro-3-nitrophenyl)methylidene]-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide
CAS 315226-28-9C14H13ClN4O3
2-(1-Methylpyrrol-2-yl)-N-[(E)-(4-nitrophenyl)methylideneamino]acetamide chemical structure, C14H14N4O3, CAS 314071-22-2
2-(1-Methylpyrrol-2-yl)-N-[(E)-(4-nitrophenyl)methylideneamino]acetamide
CAS 314071-22-2C14H14N4O3
N-[(E)-(4-Chlorophenyl)methylideneamino]-2-(1-methylpyrrol-2-yl)acetamide chemical structure, C14H14ClN3O, CAS 314071-09-5
N-[(E)-(4-Chlorophenyl)methylideneamino]-2-(1-methylpyrrol-2-yl)acetamide
CAS 314071-09-5C14H14ClN3O
2-(1-Methyl-1H-pyrrol-2-yl)-N'-(2-(trifluoromethyl)benzylidene)acetohydrazide chemical structure, C15H14F3N3O, CAS 314070-97-8
2-(1-Methyl-1H-pyrrol-2-yl)-N'-(2-(trifluoromethyl)benzylidene)acetohydrazide
CAS 314070-97-8C15H14F3N3O
N'-[(1Z)-1-(3,4-Dichlorophenyl)ethylidene]-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide chemical structure, C15H15Cl2N3O, CAS 315226-00-7
N'-[(1Z)-1-(3,4-Dichlorophenyl)ethylidene]-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide
CAS 315226-00-7C15H15Cl2N3O
N'-(1-(2-Chlorophenyl)ethylidene)-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide chemical structure, C15H16ClN3O, CAS 315226-12-1
N'-(1-(2-Chlorophenyl)ethylidene)-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide
CAS 315226-12-1C15H16ClN3O
N'-(1-(2,4-Dichlorophenyl)ethylidene)-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide chemical structure, C15H15Cl2N3O, CAS 315226-16-5
N'-(1-(2,4-Dichlorophenyl)ethylidene)-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide
CAS 315226-16-5C15H15Cl2N3O
N'-(4-Butoxy-3-ethoxybenzylidene)-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide chemical structure, C20H27N3O3, CAS 524926-27-0
N'-(4-Butoxy-3-ethoxybenzylidene)-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide
CAS 524926-27-0C20H27N3O3
2-(1-Methyl-1H-pyrrol-2-yl)-N'-{(E)-[4-(propan-2-yloxy)phenyl]methylidene}acetohydrazide chemical structure, C17H21N3O2, CAS 669731-01-5
2-(1-Methyl-1H-pyrrol-2-yl)-N'-{(E)-[4-(propan-2-yloxy)phenyl]methylidene}acetohydrazide
CAS 669731-01-5C17H21N3O2
N'-(3,5-Ditert-BU-4-hydroxybenzylidene)-2-(1-ME-1H-pyrrol-2-yl)acetohydrazide chemical structure, C22H31N3O2, CAS 314071-27-7
N'-(3,5-Ditert-BU-4-hydroxybenzylidene)-2-(1-ME-1H-pyrrol-2-yl)acetohydrazide
CAS 314071-27-7C22H31N3O2
N'-(3-Ethoxy-4-hydroxybenzylidene)-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide chemical structure, C16H19N3O3, CAS 314071-19-7
N'-(3-Ethoxy-4-hydroxybenzylidene)-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide
CAS 314071-19-7C16H19N3O3
N'-(1-(4-Hydroxyphenyl)propylidene)-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide chemical structure, C16H19N3O2, CAS 314071-34-6
N'-(1-(4-Hydroxyphenyl)propylidene)-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide
CAS 314071-34-6C16H19N3O2