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Murcko scaffold

Ring system with 2 rings and 16 atoms

48 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
48
With full pages
11
Scaffold SMILES

C(=CC1CCCC1)CCCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=CC1CCCC1)CCCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 48 chemicals

7-[3,5-Dihydroxy-2-(3-hydroxy-5-phenyl-1-penten-1-yl)cyclopentyl]-5-heptenoic acid chemical structure, C23H32O5, CAS 130273-90-4
7-[3,5-Dihydroxy-2-(3-hydroxy-5-phenyl-1-penten-1-yl)cyclopentyl]-5-heptenoic acid
CAS 130273-90-4C23H32O5
Propan-2-yl 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-hydroxy-5-phenylpent-1-enyl)cyclopentyl]hept-5-enoate chemical structure, C26H38O5
Propan-2-yl 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-hydroxy-5-phenylpent-1-enyl)cyclopentyl]hept-5-enoate
C26H38O5
Bimatoprost acid chemical structure, C23H32O5, CAS 38344-08-0
Bimatoprost acid
CAS 38344-08-0C23H32O5
(5Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl)cyclopentyl)-5-heptenamide chemical structure, C23H33NO4, CAS 155205-89-3
(5Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl)cyclopentyl)-5-heptenamide
CAS 155205-89-3C23H33NO4
17-Phenyl-trinor-PGF2alpha isopropyl ester chemical structure, C26H38O5, CAS 130209-76-6
17-Phenyl-trinor-PGF2alpha isopropyl ester
CAS 130209-76-6C26H38O5
Bimatoprost chemical structure, C25H37NO4, CAS 155206-00-1
Bimatoprost
CAS 155206-00-1C25H37NO4
(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,3R)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoic acid chemical structure, C23H32O5, CAS 41639-71-8
(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,3R)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoic acid
CAS 41639-71-8C23H32O5
15-Methyl-17-phenyl-18,19,20-trinorprostaglandin F2alpha methyl ester chemical structure, C25H36O5, CAS 102130-27-8
15-Methyl-17-phenyl-18,19,20-trinorprostaglandin F2alpha methyl ester
CAS 102130-27-8C25H36O5
5-Oxa-17-phenyl-18,19,20-trinor prostaglandin f1alpha amide chemical structure, C22H33NO5, CAS 80210-20-4
5-Oxa-17-phenyl-18,19,20-trinor prostaglandin f1alpha amide
CAS 80210-20-4C22H33NO5
Methyl 4-[2-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]ethoxy]butanoate chemical structure, C23H34O6, CAS 55444-88-7
Methyl 4-[2-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]ethoxy]butanoate
CAS 55444-88-7C23H34O6
17-Phenylprostaglandin F2alpha chemical structure, C26H38O5, CAS 55582-75-7
17-Phenylprostaglandin F2alpha
CAS 55582-75-7C26H38O5
17-(4-Azidophenyl)-18,19,20-trinorprostaglandin E2 chemical structure, C23H31N3O5, CAS 117625-46-4
17-(4-Azidophenyl)-18,19,20-trinorprostaglandin E2
CAS 117625-46-4C23H31N3O5
(E)-N-Ethyl-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)hept-5-enamide chemical structure, C25H37NO4, CAS 1163135-95-2
(E)-N-Ethyl-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)hept-5-enamide
CAS 1163135-95-2C25H37NO4
(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,3S)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]pent-1-enyl]cyclopentyl]hept-5-enoic acid chemical structure, C24H31F3O5, CAS 221246-34-0
(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,3S)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]pent-1-enyl]cyclopentyl]hept-5-enoic acid
CAS 221246-34-0C24H31F3O5
Propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-(4-methylphenyl)pent-1-enyl]cyclopentyl]hept-5-enoate chemical structure, C27H40O5, CAS 135646-99-0
Propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-(4-methylphenyl)pent-1-enyl]cyclopentyl]hept-5-enoate
CAS 135646-99-0C27H40O5
Bimatoprost isopropyl ester chemical structure, C26H38O5, CAS 130273-87-9
Bimatoprost isopropyl ester
CAS 130273-87-9C26H38O5
(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-propan-2-ylhept-5-enamide chemical structure, C26H39NO4, CAS 155205-99-5
(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-propan-2-ylhept-5-enamide
CAS 155205-99-5C26H39NO4
(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N,N-dimethylhept-5-enamide chemical structure, C25H37NO4, CAS 155205-90-6
(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N,N-dimethylhept-5-enamide
CAS 155205-90-6C25H37NO4
(E)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoic acid chemical structure, C23H32O5, CAS 1648894-84-1
(E)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoic acid
CAS 1648894-84-1C23H32O5
15(R)-17-Phenyl trinor prostaglandin F2alpha isopropyl ester chemical structure, C26H38O5
15(R)-17-Phenyl trinor prostaglandin F2alpha isopropyl ester
C26H38O5
(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-methylhept-5-enamide chemical structure, C24H35NO4, CAS 155206-01-2
(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-methylhept-5-enamide
CAS 155206-01-2C24H35NO4
Bimatoprost acid methyl ester chemical structure, C24H34O5, CAS 38315-47-8
Bimatoprost acid methyl ester
CAS 38315-47-8C24H34O5
17-Phenyl trinor prostaglandin F2alpha diethyl amide chemical structure, C27H41NO4, CAS 1176637-26-5
17-Phenyl trinor prostaglandin F2alpha diethyl amide
CAS 1176637-26-5C27H41NO4
17-Phenyl trinor prostaglandin F2alpha serinol amide chemical structure, C26H39NO6, CAS 1175838-84-2
17-Phenyl trinor prostaglandin F2alpha serinol amide
CAS 1175838-84-2C26H39NO6