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Murcko scaffold

Ring system with 4 rings and 23 atoms

131 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
131
With full pages
2
Scaffold SMILES

O=C(Nc1ccccc1)c1cn2cc(-c3ccccc3)nc2s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1cn2cc(-c3ccccc3)nc2s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 131 chemicals

N-(3,4-Dimethylphenyl)-3-methyl-6-phenylimidazo[2,1-b]thiazole-2-carboxamide chemical structure, C21H19N3OS, CAS 932995-59-0
N-(3,4-Dimethylphenyl)-3-methyl-6-phenylimidazo[2,1-b]thiazole-2-carboxamide
CAS 932995-59-0C21H19N3OS
N-(2,5-Dimethylphenyl)-3-methyl-6-phenylimidazo[2,1-b][1,3]thiazole-2-carboxamide chemical structure, C21H19N3OS, CAS 939597-86-1
N-(2,5-Dimethylphenyl)-3-methyl-6-phenylimidazo[2,1-b][1,3]thiazole-2-carboxamide
CAS 939597-86-1C21H19N3OS
N-(4-Carbamoylphenyl)-3-methyl-6-phenylimidazo[2,1-b]thiazole-2-carboxamide chemical structure, C20H16N4O2S, CAS 852133-71-2
N-(4-Carbamoylphenyl)-3-methyl-6-phenylimidazo[2,1-b]thiazole-2-carboxamide
CAS 852133-71-2C20H16N4O2S
N-[4-(Diethylamino)-2-methylphenyl]-3-methyl-6-phenylimidazo[2,1-b][1,3]thiazole-2-carboxamide chemical structure, C24H26N4OS, CAS 939635-63-9
N-[4-(Diethylamino)-2-methylphenyl]-3-methyl-6-phenylimidazo[2,1-b][1,3]thiazole-2-carboxamide
CAS 939635-63-9C24H26N4OS
N-(3,4-Difluorophenyl)-3-methyl-6-phenylimidazo[2,1-b][1,3]thiazole-2-carboxamide chemical structure, C19H13F2N3OS, CAS 852133-59-6
N-(3,4-Difluorophenyl)-3-methyl-6-phenylimidazo[2,1-b][1,3]thiazole-2-carboxamide
CAS 852133-59-6C19H13F2N3OS
6-(4-Fluorophenyl)-3-methyl-N-phenylimidazo[2,1-b][1,3]thiazole-2-carboxamide chemical structure, C19H14FN3OS, CAS 852134-19-1
6-(4-Fluorophenyl)-3-methyl-N-phenylimidazo[2,1-b][1,3]thiazole-2-carboxamide
CAS 852134-19-1C19H14FN3OS
N-(2-Fluorophenyl)-6-(4-fluorophenyl)-3-methylimidazo[2,1-b]thiazole-2-carboxamide chemical structure, C19H13F2N3OS, CAS 852134-20-4
N-(2-Fluorophenyl)-6-(4-fluorophenyl)-3-methylimidazo[2,1-b]thiazole-2-carboxamide
CAS 852134-20-4C19H13F2N3OS
N,6-bis(4-fluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide chemical structure, C19H13F2N3OS, CAS 852134-21-5
N,6-bis(4-fluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide
CAS 852134-21-5C19H13F2N3OS
6-(4-Fluorophenyl)-N-(2-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide chemical structure, C20H16FN3O2S, CAS 852134-23-7
6-(4-Fluorophenyl)-N-(2-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide
CAS 852134-23-7C20H16FN3O2S
6-(4-Fluorophenyl)-N-(3-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide chemical structure, C20H16FN3O2S, CAS 852134-24-8
6-(4-Fluorophenyl)-N-(3-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide
CAS 852134-24-8C20H16FN3O2S
N-(3-Acetylphenyl)-6-(4-fluorophenyl)-3-methylimidazo[2,1-b]thiazole-2-carboxamide chemical structure, C21H16FN3O2S, CAS 852134-28-2
N-(3-Acetylphenyl)-6-(4-fluorophenyl)-3-methylimidazo[2,1-b]thiazole-2-carboxamide
CAS 852134-28-2C21H16FN3O2S
Ethyl 4-(6-(4-fluorophenyl)-3-methylimidazo[2,1-b]thiazole-2-carboxamido)benzoate chemical structure, C22H18FN3O3S, CAS 852134-29-3
Ethyl 4-(6-(4-fluorophenyl)-3-methylimidazo[2,1-b]thiazole-2-carboxamido)benzoate
CAS 852134-29-3C22H18FN3O3S
Methyl 4-(6-(4-fluorophenyl)-3-methylimidazo[2,1-b]thiazole-2-carboxamido)benzoate chemical structure, C21H16FN3O3S, CAS 852134-30-6
Methyl 4-(6-(4-fluorophenyl)-3-methylimidazo[2,1-b]thiazole-2-carboxamido)benzoate
CAS 852134-30-6C21H16FN3O3S
Methyl 2-(6-(4-fluorophenyl)-3-methylimidazo[2,1-b]thiazole-2-carboxamido)benzoate chemical structure, C21H16FN3O3S, CAS 852134-31-7
Methyl 2-(6-(4-fluorophenyl)-3-methylimidazo[2,1-b]thiazole-2-carboxamido)benzoate
CAS 852134-31-7C21H16FN3O3S
N-(3,4-Dimethoxyphenyl)-6-(4-fluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide chemical structure, C21H18FN3O3S, CAS 852134-34-0
N-(3,4-Dimethoxyphenyl)-6-(4-fluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide
CAS 852134-34-0C21H18FN3O3S
N-(2,4-Dimethoxyphenyl)-6-(4-fluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide chemical structure, C21H18FN3O3S, CAS 852134-35-1
N-(2,4-Dimethoxyphenyl)-6-(4-fluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide
CAS 852134-35-1C21H18FN3O3S
N-(2-Carbamoylphenyl)-6-(4-fluorophenyl)-3-methylimidazo[2,1-b]thiazole-2-carboxamide chemical structure, C20H15FN4O2S, CAS 852134-43-1
N-(2-Carbamoylphenyl)-6-(4-fluorophenyl)-3-methylimidazo[2,1-b]thiazole-2-carboxamide
CAS 852134-43-1C20H15FN4O2S
N-(3-Methoxyphenyl)-6-(4-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide chemical structure, C21H19N3O3S, CAS 852134-93-1
N-(3-Methoxyphenyl)-6-(4-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide
CAS 852134-93-1C21H19N3O3S
N,6-bis(4-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide chemical structure, C21H19N3O3S, CAS 852134-94-2
N,6-bis(4-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide
CAS 852134-94-2C21H19N3O3S
N-(4-Acetylphenyl)-6-(4-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide chemical structure, C22H19N3O3S, CAS 852134-97-5
N-(4-Acetylphenyl)-6-(4-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide
CAS 852134-97-5C22H19N3O3S
N-(3-Acetylphenyl)-6-(4-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide chemical structure, C22H19N3O3S, CAS 852134-98-6
N-(3-Acetylphenyl)-6-(4-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide
CAS 852134-98-6C22H19N3O3S
Ethyl 4-(6-(4-methoxyphenyl)-3-methylimidazo[2,1-b]thiazole-2-carboxamido)benzoate chemical structure, C23H21N3O4S, CAS 852134-99-7
Ethyl 4-(6-(4-methoxyphenyl)-3-methylimidazo[2,1-b]thiazole-2-carboxamido)benzoate
CAS 852134-99-7C23H21N3O4S
Methyl 4-[6-(4-methoxyphenyl)-3-methylimidazo[2,1-B][1,3]thiazole-2-amido]benzoate chemical structure, C22H19N3O4S, CAS 852135-00-3
Methyl 4-[6-(4-methoxyphenyl)-3-methylimidazo[2,1-B][1,3]thiazole-2-amido]benzoate
CAS 852135-00-3C22H19N3O4S
N-(3,4-Dimethoxyphenyl)-6-(4-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide chemical structure, C22H21N3O4S, CAS 852135-05-8
N-(3,4-Dimethoxyphenyl)-6-(4-methoxyphenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxamide
CAS 852135-05-8C22H21N3O4S