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Murcko scaffold

Ring system with 4 rings and 19 atoms

12 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
19
Chemicals
12
With full pages
1
Scaffold SMILES

c1ccc(C2Cc3ccccc3C3=NCCN32)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(C2Cc3ccccc3C3=NCCN32)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-(p-fluorophenyl)- chemical structure, C17H15FN2O, CAS 56882-41-8
Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-(p-fluorophenyl)-
CAS 56882-41-8C17H15FN2O
Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-(p-chlorophenyl)- chemical structure, C17H15ClN2O, CAS 56882-42-9
Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-(p-chlorophenyl)-
CAS 56882-42-9C17H15ClN2O
Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-(m-fluorophenyl)- chemical structure, C17H15FN2O, CAS 56882-43-0
Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-(m-fluorophenyl)-
CAS 56882-43-0C17H15FN2O
Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-(alpha,alpha,alpha-trifluoro-m-tolyl)- chemical structure, C18H15F3N2O, CAS 56882-44-1
Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-(alpha,alpha,alpha-trifluoro-m-tolyl)-
CAS 56882-44-1C18H15F3N2O
Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-phenyl- chemical structure, C17H16N2O, CAS 56882-45-2
Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-phenyl-
CAS 56882-45-2C17H16N2O
Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-(p-tolyl)- chemical structure, C18H18N2O, CAS 56882-46-3
Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-(p-tolyl)-
CAS 56882-46-3C18H18N2O
Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-(p-methoxyphenyl)- chemical structure, C18H18N2O2, CAS 56882-47-4
Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-(p-methoxyphenyl)-
CAS 56882-47-4C18H18N2O2
Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-(3,4-dichlorophenyl)- chemical structure, C17H14Cl2N2O, CAS 56882-49-6
Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-(3,4-dichlorophenyl)-
CAS 56882-49-6C17H14Cl2N2O
Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-(o-chlorophenyl)- chemical structure, C17H15ClN2O, CAS 56882-50-9
Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-(o-chlorophenyl)-
CAS 56882-50-9C17H15ClN2O
Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-(2,4-dichlorophenyl)- chemical structure, C17H14Cl2N2O, CAS 56882-51-0
Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-(2,4-dichlorophenyl)-
CAS 56882-51-0C17H14Cl2N2O
Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-(o-fluorophenyl)- chemical structure, C17H15FN2O, CAS 84774-99-2
Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-(o-fluorophenyl)-
CAS 84774-99-2C17H15FN2O
Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-(m-chlorophenyl)- chemical structure, C17H15ClN2O, CAS 84775-00-8
Imidazo(2,1-a)isoquinolin-5-ol, 2,3,5,6-tetrahydro-5-(m-chlorophenyl)-
CAS 84775-00-8C17H15ClN2O