Murcko scaffold
Benzene, ((phenylmethyl)sulfonyl)- scaffold
418 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 16
- Chemicals
- 418
- With full pages
- 42
Scaffold SMILES
O=S(=O)(Cc1ccccc1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 96 of 418 chemicals
2-((Phenylsulfonyl)methyl)benzyl bromide
CAS 88116-02-3C14H13BrO2S
![1-Methyl-4-[(4-nitrobenzyl)sulfonyl]benzene chemical structure, C14H13NO4S, CAS 61081-32-1](/s/ONALOSSDMHSJLB-UHFFFAOYSA-N.svg)
1-Methyl-4-[(4-nitrobenzyl)sulfonyl]benzene
CAS 61081-32-1C14H13NO4S
2,4-Dichlorobenzyl 4-methylphenyl sulfone
CAS 672934-72-4C14H12Cl2O2S
![1-Chloro-2-{[(4-methylphenyl)sulfonyl]methyl}benzene chemical structure, C14H13ClO2S, CAS 642075-97-6](/s/QATZPUHVCPVXMY-UHFFFAOYSA-N.svg)
1-Chloro-2-{[(4-methylphenyl)sulfonyl]methyl}benzene
CAS 642075-97-6C14H13ClO2S
(4-Chlorobenzyl)p-tolyl sulfone
CAS 20025-49-4C14H13ClO2S
![Ethyl 4-{[(4-methylphenyl)sulfonyl]methyl}benzoate chemical structure, C17H18O4S, CAS 117687-58-8](/s/QHWBTUPDJQYVIU-UHFFFAOYSA-N.svg)
Ethyl 4-{[(4-methylphenyl)sulfonyl]methyl}benzoate
CAS 117687-58-8C17H18O4S
![Methyl 4-{[(4-methylphenyl)sulfonyl]methyl}benzoate chemical structure, C16H16O4S, CAS 117687-51-1](/s/IGDVZIOEOVDTOH-UHFFFAOYSA-N.svg)
Methyl 4-{[(4-methylphenyl)sulfonyl]methyl}benzoate
CAS 117687-51-1C16H16O4S
3,4-Dichlorobenzyl 4-methylphenyl sulfone
CAS 673452-30-7C14H12Cl2O2S
![4-{[(4-Bromophenyl)sulfonyl]methyl}benzoic acid chemical structure, C14H11BrO4S, CAS 110046-40-7](/s/DPINZJATFCJCJU-UHFFFAOYSA-N.svg)
4-{[(4-Bromophenyl)sulfonyl]methyl}benzoic acid
CAS 110046-40-7C14H11BrO4S
![Methyl 2-{[(4-methylphenyl)sulfonyl]methyl}-3-nitrobenzenecarboxylate chemical structure, C16H15NO6S, CAS 860786-92-1](/s/FOSOLKNODPTFTE-UHFFFAOYSA-N.svg)
Methyl 2-{[(4-methylphenyl)sulfonyl]methyl}-3-nitrobenzenecarboxylate
CAS 860786-92-1C16H15NO6S
![Methyl 3-nitro-2-[(phenylsulfonyl)methyl]benzenecarboxylate chemical structure, C15H13NO6S, CAS 860786-93-2](/s/CWGQFYWENLTPMS-UHFFFAOYSA-N.svg)
Methyl 3-nitro-2-[(phenylsulfonyl)methyl]benzenecarboxylate
CAS 860786-93-2C15H13NO6S
![1-{4-Nitro-3-[(phenylsulfonyl)methyl]phenyl}-1-ethanone chemical structure, C15H13NO5S, CAS 339276-51-6](/s/CCWNUWITUBGMQN-UHFFFAOYSA-N.svg)
1-{4-Nitro-3-[(phenylsulfonyl)methyl]phenyl}-1-ethanone
CAS 339276-51-6C15H13NO5S
![3-(Dimethylamino)-1-{4-nitro-3-[(phenylsulfonyl)methyl]phenyl}-2-propen-1-one chemical structure, C18H18N2O5S, CAS 339276-52-7](/s/DIJPXGOFUIRCEZ-ZHACJKMWSA-N.svg)
3-(Dimethylamino)-1-{4-nitro-3-[(phenylsulfonyl)methyl]phenyl}-2-propen-1-one
CAS 339276-52-7C18H18N2O5S
![3-{[(4-Chlorophenyl)sulfonyl]methyl}-4-nitrobenzenecarboxylic acid chemical structure, C14H10ClNO6S, CAS 339276-54-9](/s/YSMSWDDIASQMJQ-UHFFFAOYSA-N.svg)
3-{[(4-Chlorophenyl)sulfonyl]methyl}-4-nitrobenzenecarboxylic acid
CAS 339276-54-9C14H10ClNO6S
![1-(3-{[(4-Chlorophenyl)sulfonyl]methyl}-4-nitrophenyl)-1-ethanone chemical structure, C15H12ClNO5S, CAS 338956-24-4](/s/BQLSMVLABMAFQB-UHFFFAOYSA-N.svg)
1-(3-{[(4-Chlorophenyl)sulfonyl]methyl}-4-nitrophenyl)-1-ethanone
CAS 338956-24-4C15H12ClNO5S
![Methyl 3-{[(4-chlorophenyl)sulfonyl]methyl}-4-nitrobenzenecarboxylate chemical structure, C15H12ClNO6S, CAS 339016-37-4](/s/SMEOJIRAXUAZCH-UHFFFAOYSA-N.svg)
Methyl 3-{[(4-chlorophenyl)sulfonyl]methyl}-4-nitrobenzenecarboxylate
CAS 339016-37-4C15H12ClNO6S
![(2-Chlorobenzyl)[2-nitro-5-(trifluoromethyl)phenyl]dioxo-lambda~6~-sulfane chemical structure, C14H9ClF3NO4S, CAS 866132-61-8](/s/AYWNDTBQUDVDDB-UHFFFAOYSA-N.svg)
(2-Chlorobenzyl)[2-nitro-5-(trifluoromethyl)phenyl]dioxo-lambda~6~-sulfane
CAS 866132-61-8C14H9ClF3NO4S
![Ethyl 3-{[(4-chlorophenyl)sulfonyl]methyl}-4-nitrobenzenecarboxylate chemical structure, C16H14ClNO6S, CAS 339101-60-9](/s/SEHSUMOUWUIOQG-UHFFFAOYSA-N.svg)
Ethyl 3-{[(4-chlorophenyl)sulfonyl]methyl}-4-nitrobenzenecarboxylate
CAS 339101-60-9C16H14ClNO6S
![3-{[(4-Chlorophenyl)sulfonyl]methyl}-4-nitrobenzenecarboxamide chemical structure, C14H11ClN2O5S, CAS 339101-86-9](/s/BNOAWLIFSMFBFI-UHFFFAOYSA-N.svg)
3-{[(4-Chlorophenyl)sulfonyl]methyl}-4-nitrobenzenecarboxamide
CAS 339101-86-9C14H11ClN2O5S
![4-[[(4-Methylphenyl)sulfonyl]methyl]benzenamine chemical structure, C14H15NO2S, CAS 54306-15-9](/s/PAZPBJJIOPGWOO-UHFFFAOYSA-N.svg)
4-[[(4-Methylphenyl)sulfonyl]methyl]benzenamine
CAS 54306-15-9C14H15NO2S
![2-Bromo-1-[(4-methylphenyl)sulfonylmethyl]-4-nitrobenzene chemical structure, C14H12BrNO4S, CAS 593272-33-4](/s/MWMRBXNCDRHBPG-UHFFFAOYSA-N.svg)
2-Bromo-1-[(4-methylphenyl)sulfonylmethyl]-4-nitrobenzene
CAS 593272-33-4C14H12BrNO4S
![2-[(4-Methylbenzene-1-sulfonyl)methyl]-4-nitrophenol chemical structure, C14H13NO5S, CAS 7066-53-7](/s/KIMFKAVCLNDLPT-UHFFFAOYSA-N.svg)
2-[(4-Methylbenzene-1-sulfonyl)methyl]-4-nitrophenol
CAS 7066-53-7C14H13NO5S
![Benzene, 4-chloro-1-nitro-2-[(phenylsulfonyl)methyl]- chemical structure, C13H10ClNO4S, CAS 89303-10-6](/s/HZDABTBFYUKBPE-UHFFFAOYSA-N.svg)
Benzene, 4-chloro-1-nitro-2-[(phenylsulfonyl)methyl]-
CAS 89303-10-6C13H10ClNO4S
Phenyl(4-methylbenzyl) sulfone
CAS 19523-24-1C14H14O2S
- 4-[[(4-Chloro-2,5-dimethylphenyl)sulfonyl]methyl]aniline261965-48-4C15H16ClNO2S
- 4-Nitro-3-((phenylsulfonyl)methyl)benzaldehyde339276-48-1C14H11NO5S
- 2-Bromo-1-(3-(((4-chlorophenyl)sulfonyl)methyl)-4-nitrophenyl)-1-ethanone303145-53-1C15H11BrClNO5S
- 1-(Isocyano(tosyl)methyl)-2-methoxybenzene263389-53-3C16H15NO3S
- a-Tosyl-(3-methoxybenzyl) isocyanide394655-17-5C16H15NO3S
- a-Tosyl-(4-methoxybenzyl) isocyanide263389-54-4C16H15NO3S
- 1 suppliers4-(Isocyano(tosyl)methyl)-1,2-dimethoxybenzene943614-50-4C17H17NO4S
- 1 suppliers5-[Isocyano(4-methylbenzenesulfonyl)methyl]-1,2,3-trimethoxybenzene324519-54-2C18H19NO5S
- Methyl 3-[isocyano(4-methylbenzenesulfonyl)methyl]benzoate1008771-33-2C17H15NO4S
- 1-(Isocyano(tosyl)methyl)-3-nitrobenzene1029104-25-3C15H12N2O4S
- Isocyano(2-tert-butylsulphanylphenyl)methyl-4-methylphenyl sulphone1029104-30-0C19H21NO2S2
- 2,4-Dichloro-1-(isocyano(tosyl)methyl)benzene952727-77-4C15H11Cl2NO2S
- 1-Chloro-2-(isocyano(tosyl)methyl)benzene1029104-34-4C15H12ClNO2S
- a-Tosyl-(4-bromobenzyl) isocyanide655254-61-8C15H12BrNO2S
- 1-Bromo-3-(isocyano(tosyl)methyl)benzene655256-70-5C15H12BrNO2S
- Ethyl 2-[2-[(4-chlorophenyl)sulfonylmethyl]phenoxy]acetate175202-86-5C17H17ClO5S
- Benzene, 4-(methylthio)-1-nitro-2-[(phenylsulfonyl)methyl]-89303-16-2C14H13NO4S2
- Benzoic acid, 4-nitro-3-[(phenylsulfonyl)methyl]-89303-23-1C14H11NO6S
- 3-[(4-Chlorophenyl)sulfonylmethyl]-N'-hydroxybenzenecarboximidamide583059-52-3C14H13ClN2O3S
- 1,3-Dichloro-2-[[(4-methylphenyl)sulfonyl]methyl]benzene341021-41-8C14H12Cl2O2S
- 4-Phenyl-4-(phenylsulfonyl)butan-2-one62692-46-0C16H16O3S
- 4-(4-Nitrophenyl)sulfonyl-4-phenylbutan-2-one300376-96-9C16H15NO5S
- 1-Fluoro-2-{[(4-methylphenyl)sulfonyl]methyl}benzene61081-31-0C14H13FO2S
- 1-Bromo-4-{[(4-methylphenyl)sulfonyl]methyl}benzene26885-97-2C14H13BrO2S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)c1ccccc11,973 chemicals
O=S(=O)(Nc1ccccc1)c1ccccc1978 chemicals
c1ccc(COc2ccccc2)cc1829 chemicals
c1ccc(N=Nc2ccccc2)cc1383 chemicals
C(=Nc1ccccc1)c1ccccc1379 chemicals
O=C(Oc1ccccc1)c1ccccc1309 chemicals
c1ccc(CNc2ccccc2)cc1309 chemicals
C(=Cc1ccccc1)c1ccccc1279 chemicals
c1ccc(CCc2ccccc2)cc1264 chemicals
O=C(Nc1ccccc1)c1cccnc1140 chemicals
O=C(Cc1ccccc1)c1ccccc1137 chemicals
O=C(Nc1ccccn1)c1ccccc1120 chemicals