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Murcko scaffold

Benzene, ((phenylmethyl)sulfonyl)- scaffold

418 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
418
With full pages
42
Scaffold SMILES

O=S(=O)(Cc1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Benzene, ((phenylmethyl)sulfonyl)- page
Murcko scaffold O=S(=O)(Cc1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 144 of 418 chemicals

3-Hydroxy-2-[[2-(hydroxymethyl)phenyl]sulfonylmethyl]benzenesulfonic acid chemical structure, C14H14O7S2, CAS 94248-30-3
3-Hydroxy-2-[[2-(hydroxymethyl)phenyl]sulfonylmethyl]benzenesulfonic acid
CAS 94248-30-3C14H14O7S2
4-((4-Methylphenyl)sulfonyl)-4-phenyl-2-butanone chemical structure, C17H18O3S, CAS 33866-93-2
4-((4-Methylphenyl)sulfonyl)-4-phenyl-2-butanone
CAS 33866-93-2C17H18O3S
4-Phenylmethanesulfonylbenzoic acid chemical structure, C14H12O4S, CAS 70793-11-2
4-Phenylmethanesulfonylbenzoic acid
CAS 70793-11-2C14H12O4S
3-{[(4-Chlorophenyl)sulfonyl]methyl}-4-nitrobenzenecarbonitrile chemical structure, C14H9ClN2O4S, CAS 339101-92-7
3-{[(4-Chlorophenyl)sulfonyl]methyl}-4-nitrobenzenecarbonitrile
CAS 339101-92-7C14H9ClN2O4S
5-Methyl-2-[(phenylmethyl)sulfonyl]benzeneacetic acid chemical structure, C16H16O4S, CAS 383135-70-4
5-Methyl-2-[(phenylmethyl)sulfonyl]benzeneacetic acid
CAS 383135-70-4C16H16O4S
[4-(Benzylsulfonyl)phenyl]acetic acid chemical structure, C15H14O4S, CAS 383135-49-7
[4-(Benzylsulfonyl)phenyl]acetic acid
CAS 383135-49-7C15H14O4S
Benzyl[2-nitro-5-(trifluoromethyl)phenyl]dioxo-lambda~6~-sulfane chemical structure, C14H10F3NO4S, CAS 866137-59-9
Benzyl[2-nitro-5-(trifluoromethyl)phenyl]dioxo-lambda~6~-sulfane
CAS 866137-59-9C14H10F3NO4S
Methyl 4-amino-3-{[(4-chlorophenyl)sulfonyl]methyl}benzenecarboxylate chemical structure, C15H14ClNO4S, CAS 339016-38-5
Methyl 4-amino-3-{[(4-chlorophenyl)sulfonyl]methyl}benzenecarboxylate
CAS 339016-38-5C15H14ClNO4S
3-{[(4-Chlorophenyl)sulfonyl]methyl}-4-nitrobenzenecarbohydrazide chemical structure, C14H12ClN3O5S, CAS 339016-39-6
3-{[(4-Chlorophenyl)sulfonyl]methyl}-4-nitrobenzenecarbohydrazide
CAS 339016-39-6C14H12ClN3O5S
3-{[(4-Chlorophenyl)sulfonyl]methyl}-N-[(dimethylamino)methylene]-4-nitrobenzenecarboxamide chemical structure, C17H16ClN3O5S, CAS 1164481-20-2
3-{[(4-Chlorophenyl)sulfonyl]methyl}-N-[(dimethylamino)methylene]-4-nitrobenzenecarboxamide
CAS 1164481-20-2C17H16ClN3O5S
1-Methyl-2-[(phenylsulfonyl)methyl]benzene chemical structure, C14H14O2S, CAS 71996-48-0
1-Methyl-2-[(phenylsulfonyl)methyl]benzene
CAS 71996-48-0C14H14O2S
Alpha,alpha-dimethyl-4-nitrobenzyl phenyl sulfone chemical structure, C15H15NO4S, CAS 70951-74-5
Alpha,alpha-dimethyl-4-nitrobenzyl phenyl sulfone
CAS 70951-74-5C15H15NO4S
1-[1-(Benzenesulfonyl)ethyl]-4-nitrobenzene chemical structure, C14H13NO4S, CAS 93213-73-1
1-[1-(Benzenesulfonyl)ethyl]-4-nitrobenzene
CAS 93213-73-1C14H13NO4S
2-[(Benzenesulfonyl)methyl]benzoic acid chemical structure, C14H12O4S, CAS 300396-14-9
2-[(Benzenesulfonyl)methyl]benzoic acid
CAS 300396-14-9C14H12O4S
2-(3-Benzylsulfonyl-5-nitrophenyl)sulfanylacetic acid chemical structure, C15H13NO6S2, CAS 883291-52-9
2-(3-Benzylsulfonyl-5-nitrophenyl)sulfanylacetic acid
CAS 883291-52-9C15H13NO6S2
Benzenamine, N,N-dimethyl-4-[[(4-nitrophenyl)sulfonyl]methyl]- chemical structure, C15H16N2O4S, CAS 33933-61-8
Benzenamine, N,N-dimethyl-4-[[(4-nitrophenyl)sulfonyl]methyl]-
CAS 33933-61-8C15H16N2O4S
2-(1-(Phenylsulfonyl)ethyl)benzoic acid chemical structure, C15H14O4S, CAS 446011-65-0
2-(1-(Phenylsulfonyl)ethyl)benzoic acid
CAS 446011-65-0C15H14O4S
1-(3-(((4-Chlorophenyl)sulfonyl)methyl)-4-nitrophenyl)-3-(dimethylamino)-2-propen-1-one chemical structure, C18H17ClN2O5S, CAS 303145-49-5
1-(3-(((4-Chlorophenyl)sulfonyl)methyl)-4-nitrophenyl)-3-(dimethylamino)-2-propen-1-one
CAS 303145-49-5C18H17ClN2O5S
1-(3-(((4-Chlorophenyl)sulfonyl)methyl)-4-nitrophenyl)-1-ethanone o-(3-chloro-2-propenyl)oxime chemical structure, C18H16Cl2N2O5S, CAS 339016-34-1
1-(3-(((4-Chlorophenyl)sulfonyl)methyl)-4-nitrophenyl)-1-ethanone o-(3-chloro-2-propenyl)oxime
CAS 339016-34-1C18H16Cl2N2O5S
2-[(4-Fluorobenzyl)sulfonyl]benzoic acid chemical structure, C14H11FO4S, CAS 341933-13-9
2-[(4-Fluorobenzyl)sulfonyl]benzoic acid
CAS 341933-13-9C14H11FO4S
Benzene, 1-methoxy-3-[(phenylsulfonyl)methyl]- chemical structure, C14H14O3S, CAS 129527-19-1
Benzene, 1-methoxy-3-[(phenylsulfonyl)methyl]-
CAS 129527-19-1C14H14O3S
3-(3-{[(4-Chlorophenyl)sulfonyl]methyl}-4-nitrophenyl)-3-oxopropanal O-methyloxime chemical structure, C17H15ClN2O6S, CAS 303145-56-4
3-(3-{[(4-Chlorophenyl)sulfonyl]methyl}-4-nitrophenyl)-3-oxopropanal O-methyloxime
CAS 303145-56-4C17H15ClN2O6S
2-(((4-Chlorophenyl)sulfonyl)methyl)-1,4-difluorobenzene chemical structure, C13H9ClF2O2S, CAS 470716-51-9
2-(((4-Chlorophenyl)sulfonyl)methyl)-1,4-difluorobenzene
CAS 470716-51-9C13H9ClF2O2S
(Benzenesulfonylphenylmethyl)carbamic acid tert-butyl ester chemical structure, C18H21NO4S, CAS 155396-71-7
(Benzenesulfonylphenylmethyl)carbamic acid tert-butyl ester
CAS 155396-71-7C18H21NO4S