Murcko scaffold
Benzene, ((phenylmethyl)sulfonyl)- scaffold
418 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 16
- Chemicals
- 418
- With full pages
- 42
Scaffold SMILES
O=S(=O)(Cc1ccccc1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 145 to 192 of 418 chemicals
N-((3-Bromophenyl)(tosyl)methyl)formamide
CAS 655254-60-7C15H14BrNO3S
2-(Phenylsulfonylmethyl)benzaldehyde
CAS 468751-38-4C14H12O3S
tert-Butyl ((4-cyanophenyl)(phenylsulfonyl)methyl)carbamate
CAS 774225-24-0C19H20N2O4S
![Benzene, [[(methylthio)phenylmethyl]sulfonyl]- chemical structure, C14H14O2S2, CAS 102677-59-8](/s/LLNLTVAOJGSOPR-UHFFFAOYSA-N.svg)
Benzene, [[(methylthio)phenylmethyl]sulfonyl]-
CAS 102677-59-8C14H14O2S2
Agn-PC-0nhund
CAS 42604-84-2C14H12N2O6S
![N-[(4-Bromophenyl)(toluene-4-sulfonyl)methyl]formamide chemical structure, C15H14BrNO3S, CAS 655254-74-3](/s/BVCWSAQVSPBQLY-UHFFFAOYSA-N.svg)
N-[(4-Bromophenyl)(toluene-4-sulfonyl)methyl]formamide
CAS 655254-74-3C15H14BrNO3S
methyl]- chemical structure, C15H14N2O5S, CAS 850011-51-7](/s/ZIRGPAADGQNNCX-UHFFFAOYSA-N.svg)
Formamide, N-[[(4-methylphenyl)sulfonyl](4-nitrophenyl)methyl]-
CAS 850011-51-7C15H14N2O5S
![Benzene, 1-methoxy-4-[[(4-methylphenyl)sulfonyl]methyl]- chemical structure, C15H16O3S, CAS 58680-51-6](/s/GZPLNWAGCNDATQ-UHFFFAOYSA-N.svg)
Benzene, 1-methoxy-4-[[(4-methylphenyl)sulfonyl]methyl]-
CAS 58680-51-6C15H16O3S
![Phenol, 2-methoxy-4-[(phenylsulfonyl)methyl]- chemical structure, C14H14O4S, CAS 59770-86-4](/s/LDGPDRCGVLDTRW-UHFFFAOYSA-N.svg)
Phenol, 2-methoxy-4-[(phenylsulfonyl)methyl]-
CAS 59770-86-4C14H14O4S
![Phenol, 2,6-dimethoxy-4-[(phenylsulfonyl)methyl]- chemical structure, C15H16O5S, CAS 59770-87-5](/s/GDVFNUAGIXMWOG-UHFFFAOYSA-N.svg)
Phenol, 2,6-dimethoxy-4-[(phenylsulfonyl)methyl]-
CAS 59770-87-5C15H16O5S
Ethyl 3-phenyl-3-(phenylsulfonyl)propanoate
CAS 60156-18-5C17H18O4S
![Phenol, 2,6-dimethyl-4-[(phenylsulfonyl)methyl]- chemical structure, C15H16O3S, CAS 61563-84-6](/s/GYKKIRDWZNHVQU-UHFFFAOYSA-N.svg)
Phenol, 2,6-dimethyl-4-[(phenylsulfonyl)methyl]-
CAS 61563-84-6C15H16O3S
![Phenol, 2,6-dimethoxy-4-[1-(phenylsulfonyl)ethyl]- chemical structure, C16H18O5S, CAS 61563-85-7](/s/YVUPQJPGZXWHJJ-UHFFFAOYSA-N.svg)
Phenol, 2,6-dimethoxy-4-[1-(phenylsulfonyl)ethyl]-
CAS 61563-85-7C16H18O5S
![Phenol, 2,6-bis(1,1-dimethylethyl)-4-[(phenylsulfonyl)methyl]- chemical structure, C21H28O3S, CAS 60285-80-5](/s/RXIRAFBKJQJKPI-UHFFFAOYSA-N.svg)
Phenol, 2,6-bis(1,1-dimethylethyl)-4-[(phenylsulfonyl)methyl]-
CAS 60285-80-5C21H28O3S
![Phenol, 2,6-bis(1,1-dimethylethyl)-4-[1-(phenylsulfonyl)ethyl]- chemical structure, C22H30O3S, CAS 60131-46-6](/s/OWSYDANGUICYNG-UHFFFAOYSA-N.svg)
Phenol, 2,6-bis(1,1-dimethylethyl)-4-[1-(phenylsulfonyl)ethyl]-
CAS 60131-46-6C22H30O3S
![Phenol, 2,6-bis(1,1-dimethylethyl)-4-[1-methyl-1-(phenylsulfonyl)ethyl]- chemical structure, C23H32O3S, CAS 60131-47-7](/s/GXQBEMHPYFWUMM-UHFFFAOYSA-N.svg)
Phenol, 2,6-bis(1,1-dimethylethyl)-4-[1-methyl-1-(phenylsulfonyl)ethyl]-
CAS 60131-47-7C23H32O3S
![Disulfide, ethyl (4-methoxyphenyl)[(4-methylphenyl)sulfonyl]methyl chemical structure, C17H20O3S3, CAS 61885-82-3](/s/JZMRKXZGEQTJQG-UHFFFAOYSA-N.svg)
Disulfide, ethyl (4-methoxyphenyl)[(4-methylphenyl)sulfonyl]methyl
CAS 61885-82-3C17H20O3S3
![4-{[(4-Methylphenyl)sulfonyl]methyl}benzonitrile chemical structure, C15H13NO2S, CAS 59475-60-4](/s/POWSRQJDCDYGKM-UHFFFAOYSA-N.svg)
4-{[(4-Methylphenyl)sulfonyl]methyl}benzonitrile
CAS 59475-60-4C15H13NO2S
![1-[1-(Benzenesulfonyl)propyl]-4-nitrobenzene chemical structure, C15H15NO4S, CAS 69709-35-9](/s/OABSVTPVLHTSLC-UHFFFAOYSA-N.svg)
1-[1-(Benzenesulfonyl)propyl]-4-nitrobenzene
CAS 69709-35-9C15H15NO4S
![2-[(Benzenesulfonyl)methyl]-4-bromo-1-nitrobenzene chemical structure, C13H10BrNO4S, CAS 69709-38-2](/s/LUDFITQWQQNVGC-UHFFFAOYSA-N.svg)
2-[(Benzenesulfonyl)methyl]-4-bromo-1-nitrobenzene
CAS 69709-38-2C13H10BrNO4S
![2-[(Benzenesulfonyl)methyl]-4-methoxy-1-nitrobenzene chemical structure, C14H13NO5S, CAS 69709-39-3](/s/LYXFDNRZHVQSMF-UHFFFAOYSA-N.svg)
2-[(Benzenesulfonyl)methyl]-4-methoxy-1-nitrobenzene
CAS 69709-39-3C14H13NO5S
5-Chloro-2-phenylmethanesulfonylaniline
CAS 74462-42-3C13H12ClNO2S
4-Phenylmethanesulfonylaniline
CAS 42497-99-4C13H13NO2S
![2-[(Benzenesulfonyl)methyl]-1-(bromomethyl)-3-methoxybenzene chemical structure, C15H15BrO3S, CAS 88116-09-0](/s/XVDGJLBPEONQOA-UHFFFAOYSA-N.svg)
2-[(Benzenesulfonyl)methyl]-1-(bromomethyl)-3-methoxybenzene
CAS 88116-09-0C15H15BrO3S
- 1-[(Benzenesulfonyl)methyl]-2-(bromomethyl)-3-methoxybenzene88116-10-3C15H15BrO3S
- 1-[(Benzenesulfonyl)methyl]-2-(bromomethyl)-4-methoxybenzene88116-11-4C15H15BrO3S
- 1-[(Benzenesulfonyl)methyl]-2-(pent-4-EN-1-yl)benzene88116-24-9C18H20O2S
- 2-[(Benzenesulfonyl)methyl]-4-fluoro-1-nitrobenzene89303-18-4C13H10FNO4S
- 1-(Benzenesulfonyl)-1-(4-methoxyphenyl)-4-methylpent-3-en-2-one88958-85-4C19H20O4S
- 1-[1-(Benzenesulfonyl)-3-methylbut-2-en-1-yl]-4-nitrobenzene88958-90-1C17H17NO4S
- 4-[1-(Benzenesulfonyl)-3-methylbut-2-en-1-yl]-2-chloro-1-nitrobenzene88958-91-2C17H16ClNO4S
- 1-(Benzenesulfonyl)-4-methyl-1-phenylpent-3-en-2-one88958-87-6C18H18O3S
- 2,6-Dibromo-4-(phenylmethanesulfonyl)aniline88149-50-2C13H11Br2NO2S
- 3-[(Benzenesulfonyl)methyl]-N,N-dimethyl-4-nitroaniline89303-11-7C15H16N2O4S
- 2-[(Benzenesulfonyl)methyl]-4-ethyl-1-nitrobenzene89303-13-9C15H15NO4S
- 2-[(Benzenesulfonyl)methyl]-4-tert-butyl-1-nitrobenzene89303-14-0C17H19NO4S
- 2-[(Benzenesulfonyl)methyl]-4-iodo-1-nitrobenzene89303-17-3C13H10INO4S
- 2-[(Benzenesulfonyl)methyl]-1,4-dinitrobenzene89303-19-5C13H10N2O6S
- 3-[(Benzenesulfonyl)methyl]-4-nitrobenzonitrile89303-20-8C14H10N2O4S
- 2-[(Benzenesulfonyl)methyl]-1-nitro-4-(trifluoromethyl)benzene89303-21-9C14H10F3NO4S
- 2-[(Benzenesulfonyl)methyl]-4-(methanesulfonyl)-1-nitrobenzene89303-22-0C14H13NO6S2
- 4-[(Benzenesulfonyl)methyl]-2-chloro-1-nitrobenzene86434-25-5C13H10ClNO4S
- 5-[(Benzenesulfonyl)methyl]-N,N-dimethyl-2-nitroaniline89303-24-2C15H16N2O4S
- 4-[(Benzenesulfonyl)methyl]-2-methoxy-1-nitrobenzene89303-25-3C14H13NO5S
- 4-[(Benzenesulfonyl)methyl]-1,2-dinitrobenzene89303-29-7C13H10N2O6S
- 4-[(Benzenesulfonyl)methyl]-1-nitro-2-(trifluoromethyl)benzene89303-28-6C14H10F3NO4S
- 1-[(Benzenesulfonyl)methyl]-3-chloro-2-nitrobenzene86434-29-9C13H10ClNO4S
- 3-[(Benzenesulfonyl)methyl]-N,N-dimethyl-2-nitroaniline89303-30-0C15H16N2O4S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)c1ccccc11,973 chemicals
O=S(=O)(Nc1ccccc1)c1ccccc1978 chemicals
c1ccc(COc2ccccc2)cc1829 chemicals
c1ccc(N=Nc2ccccc2)cc1383 chemicals
C(=Nc1ccccc1)c1ccccc1379 chemicals
O=C(Oc1ccccc1)c1ccccc1309 chemicals
c1ccc(CNc2ccccc2)cc1309 chemicals
C(=Cc1ccccc1)c1ccccc1279 chemicals
c1ccc(CCc2ccccc2)cc1264 chemicals
O=C(Nc1ccccc1)c1cccnc1140 chemicals
O=C(Cc1ccccc1)c1ccccc1137 chemicals
O=C(Nc1ccccn1)c1ccccc1120 chemicals