Murcko scaffold
Benzene, ((phenylmethyl)sulfonyl)- scaffold
418 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 16
- Chemicals
- 418
- With full pages
- 42
Scaffold SMILES
O=S(=O)(Cc1ccccc1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 337 to 384 of 418 chemicals
![5-Bromo-2-[(4-fluorobenzene-1-sulfonyl)methyl]aniline chemical structure, C13H11BrFNO2S, CAS 651780-36-8](/s/OEUVPZJLWGSSSX-UHFFFAOYSA-N.svg)
5-Bromo-2-[(4-fluorobenzene-1-sulfonyl)methyl]aniline
CAS 651780-36-8C13H11BrFNO2S
3-(4-((2-Methylbenzyl)sulfonyl)phenyl)hex-4-ynoic acid
CAS 865232-04-8C20H20O4S
![2-[1-(4-Chlorobenzene-1-sulfonyl)but-3-en-1-yl]-1,4-difluorobenzene chemical structure, C16H13ClF2O2S, CAS 470716-43-9](/s/LTCJUDFKHPRAOS-UHFFFAOYSA-N.svg)
2-[1-(4-Chlorobenzene-1-sulfonyl)but-3-en-1-yl]-1,4-difluorobenzene
CAS 470716-43-9C16H13ClF2O2S
![2-[(2-Methylbenzenesulfonyl)methyl]benzoic acid chemical structure, C15H14O4S, CAS 1184738-48-4](/s/CUDMYMSCGHQQSX-UHFFFAOYSA-N.svg)
2-[(2-Methylbenzenesulfonyl)methyl]benzoic acid
CAS 1184738-48-4C15H14O4S
![3-[(2-Methylbenzenesulfonyl)methyl]aniline chemical structure, C14H15NO2S, CAS 1178417-23-6](/s/ZXKQUPJZQNEQMO-UHFFFAOYSA-N.svg)
3-[(2-Methylbenzenesulfonyl)methyl]aniline
CAS 1178417-23-6C14H15NO2S
![4-[(3-Bromophenyl)methanesulfonyl]aniline chemical structure, C13H12BrNO2S, CAS 1291593-98-0](/s/DCOGBZRGNXBOLH-UHFFFAOYSA-N.svg)
4-[(3-Bromophenyl)methanesulfonyl]aniline
CAS 1291593-98-0C13H12BrNO2S
![4-[(4-Bromophenyl)methanesulfonyl]aniline chemical structure, C13H12BrNO2S, CAS 1308525-50-9](/s/JIIJUJPNGPJEBF-UHFFFAOYSA-N.svg)
4-[(4-Bromophenyl)methanesulfonyl]aniline
CAS 1308525-50-9C13H12BrNO2S
![4-[(2-Bromophenyl)methanesulfonyl]aniline chemical structure, C13H12BrNO2S, CAS 1293168-21-4](/s/GDOHPXQFDCMNTK-UHFFFAOYSA-N.svg)
4-[(2-Bromophenyl)methanesulfonyl]aniline
CAS 1293168-21-4C13H12BrNO2S
4-(1-Phenylethanesulfonyl)benzoic acid
CAS 1407473-35-1C15H14O4S
![1-Fluoro-2-[(4-methoxyphenyl)methanesulfonyl]benzene chemical structure, C14H13FO3S, CAS 652171-20-5](/s/HGQLHRJIJNWLMH-UHFFFAOYSA-N.svg)
1-Fluoro-2-[(4-methoxyphenyl)methanesulfonyl]benzene
CAS 652171-20-5C14H13FO3S
![1-Fluoro-4-[[(4-nitrophenyl)methyl]sulfonyl]benzene chemical structure, C13H10FNO4S, CAS 383-45-9](/s/YEILCJVWAIEVDW-UHFFFAOYSA-N.svg)
1-Fluoro-4-[[(4-nitrophenyl)methyl]sulfonyl]benzene
CAS 383-45-9C13H10FNO4S
![4-Fluoro-2-[(2-fluorobenzene-1-sulfonyl)methyl]-1-nitrobenzene chemical structure, C13H9F2NO4S, CAS 1253422-46-6](/s/ZYDGDTCUKQNXBO-UHFFFAOYSA-N.svg)
4-Fluoro-2-[(2-fluorobenzene-1-sulfonyl)methyl]-1-nitrobenzene
CAS 1253422-46-6C13H9F2NO4S
![N-[(4-Methylbenzene-1-sulfonyl)(phenyl)methyl]acetamide chemical structure, C16H17NO3S, CAS 185244-08-0](/s/IKMVOCASLGGGHO-UHFFFAOYSA-N.svg)
N-[(4-Methylbenzene-1-sulfonyl)(phenyl)methyl]acetamide
CAS 185244-08-0C16H17NO3S
1-Fluoro-3-(phenylmethanesulfonyl)benzene
CAS 1020734-56-8C13H11FO2S
![2-Chloro-1-fluoro-4-[(3-fluorobenzyl)sulfonyl]benzene chemical structure, C13H9ClF2O2S, CAS 934242-04-3](/s/AQPJAMIVSLFSKG-UHFFFAOYSA-N.svg)
2-Chloro-1-fluoro-4-[(3-fluorobenzyl)sulfonyl]benzene
CAS 934242-04-3C13H9ClF2O2S
4-(Benzylsulfonyl)-2-chloro-1-fluorobenzene
CAS 934241-83-5C13H10ClFO2S
![2-Chloro-1-fluoro-4-[(4-fluorobenzyl)sulfonyl]benzene chemical structure, C13H9ClF2O2S, CAS 934241-82-4](/s/BCXGPMNNFPLHMC-UHFFFAOYSA-N.svg)
2-Chloro-1-fluoro-4-[(4-fluorobenzyl)sulfonyl]benzene
CAS 934241-82-4C13H9ClF2O2S
![2-Chloro-1-fluoro-4-[(2-fluorobenzyl)sulfonyl]benzene chemical structure, C13H9ClF2O2S, CAS 934242-00-9](/s/HNXINFWRODIUPN-UHFFFAOYSA-N.svg)
2-Chloro-1-fluoro-4-[(2-fluorobenzyl)sulfonyl]benzene
CAS 934242-00-9C13H9ClF2O2S
2-Methoxy-4-(phenylmethanesulfonyl)aniline
CAS 59823-86-8C14H15NO3S
![Methyl [(benzenesulfonyl)(phenyl)methyl]carbamate chemical structure, C15H15NO4S, CAS 478660-34-3](/s/BLJDVGDSYGNWNV-UHFFFAOYSA-N.svg)
Methyl [(benzenesulfonyl)(phenyl)methyl]carbamate
CAS 478660-34-3C15H15NO4S
1-(Benzenesulfonyl)-4-methyl-1-(4-methylphenyl)pent-3-en-2-one
CAS 88958-88-7C19H20O3S
![1-[1-(Benzenesulfonyl)propyl]-2,4-dinitrobenzene chemical structure, C15H14N2O6S, CAS 89303-57-1](/s/DHHNPOUYBAFFTN-UHFFFAOYSA-N.svg)
1-[1-(Benzenesulfonyl)propyl]-2,4-dinitrobenzene
CAS 89303-57-1C15H14N2O6S
![2-[(Benzenesulfonyl)methyl]-3,6-dinitrophenol chemical structure, C13H10N2O7S, CAS 92241-29-7](/s/JVPYSGZBIYAQKG-UHFFFAOYSA-N.svg)
2-[(Benzenesulfonyl)methyl]-3,6-dinitrophenol
CAS 92241-29-7C13H10N2O7S
![N-[2-Methoxy-5-(phenylmethanesulfonyl)phenyl]propanamide chemical structure, C17H19NO4S, CAS 92921-33-0](/s/BKKPLYOABHWTGW-UHFFFAOYSA-N.svg)
N-[2-Methoxy-5-(phenylmethanesulfonyl)phenyl]propanamide
CAS 92921-33-0C17H19NO4S
- 1-[(Benzenesulfonyl)methyl]-2-isocyano-4-nitrobenzene94012-42-7C14H10N2O4S
- 1-[(Benzenesulfonyl)methyl]-2-(bromomethyl)-3-methylbenzene96964-50-0C15H15BrO2S
- 2-Chloro-4-(phenylmethanesulfonyl)phenol107624-69-1C13H11ClO3S
- 1-Methyl-4-[nitro(phenyl)methanesulfonyl]benzene21272-79-7C14H13NO4S
- 1-[(4-Methylbenzene-1-sulfonyl)methyl]-2,4-dinitrobenzene53999-08-9C14H12N2O6S
- Acetic acid--4-(benzenesulfonyl)-4-phenylbut-1-en-1-ol (1/1)62692-58-4C18H20O5S
- 5-(Benzenesulfonyl)-5-phenylpentan-2-one62692-49-3C17H18O3S
- [1-(Benzenesulfonyl)-4-chloropent-3-en-1-yl]benzene62692-32-4C17H17ClO2S
- [1-(Benzenesulfonyl)-4-chlorobut-3-en-1-yl]benzene62692-30-2C16H15ClO2S
- [1-(Benzenesulfonyl)-3-bromobut-3-en-1-yl]benzene62692-29-9C16H15BrO2S
- [1-(Benzenesulfonyl)-3-chlorobut-3-en-1-yl]benzene62692-28-8C16H15ClO2S
- 2-[(Benzenesulfonyl)methyl]-1,3-difluorobenzene705966-16-1C13H10F2O2S
- 1-[(Benzenesulfonyl)methyl]-3-iodobenzene832744-17-9C13H11IO2S
- N-[(4-Chlorobenzene-1-sulfonyl)(phenyl)methyl]formamide921767-41-1C14H12ClNO3S
- 4-[(4-Chlorophenyl)methanesulfonyl]-2-nitrophenol58880-50-5C13H10ClNO5S
- 1-Chloro-4-[(4-chlorophenyl)methanesulfonyl]-2-nitrobenzene58880-49-2C13H9Cl2NO4S
- 3-[(Benzenesulfonyl)methyl]-N-(prop-2-yn-1-yl)aniline1424384-13-3C16H15NO2S
- 2-(Benzenesulfonylmethyl)-N-prop-2-ynylaniline1436129-86-0C16H15NO2S
- 2-(4-Bromo-benzenesulfonylmethyl)-benzoic acid methyl ester1548464-23-8C15H13BrO4S
- 1-Bromo-3-fluoro-5-(((2-fluorophenyl)sulfonyl)methyl)benzene1535435-96-1C13H9BrF2O2S
- 1-Bromo-3-fluoro-5-(((4-fluorophenyl)sulfonyl)methyl)benzene1542371-35-6C13H9BrF2O2S
- 1-Bromo-3-fluoro-5-(((3-fluorophenyl)sulfonyl)methyl)benzene1540362-85-3C13H9BrF2O2S
- 4-(((3-Fluorophenyl)sulfonyl)methyl)phenol1513543-11-7C13H11FO3S
- 4-(Benzylsulfonyl)-2-methylaniline1512502-67-8C14H15NO2S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)c1ccccc11,973 chemicals
O=S(=O)(Nc1ccccc1)c1ccccc1978 chemicals
c1ccc(COc2ccccc2)cc1829 chemicals
c1ccc(N=Nc2ccccc2)cc1383 chemicals
C(=Nc1ccccc1)c1ccccc1379 chemicals
O=C(Oc1ccccc1)c1ccccc1309 chemicals
c1ccc(CNc2ccccc2)cc1309 chemicals
C(=Cc1ccccc1)c1ccccc1279 chemicals
c1ccc(CCc2ccccc2)cc1264 chemicals
O=C(Nc1ccccc1)c1cccnc1140 chemicals
O=C(Cc1ccccc1)c1ccccc1137 chemicals
O=C(Nc1ccccn1)c1ccccc1120 chemicals