Murcko scaffold
Benzene, ((phenylmethyl)sulfonyl)- scaffold
418 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 16
- Chemicals
- 418
- With full pages
- 42
Scaffold SMILES
O=S(=O)(Cc1ccccc1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 241 to 288 of 418 chemicals
![3-[(Benzenesulfonyl)methyl]benzoic acid chemical structure, C14H12O4S, CAS 142730-34-5](/s/LLWFJPNVHXHZMD-UHFFFAOYSA-N.svg)
3-[(Benzenesulfonyl)methyl]benzoic acid
CAS 142730-34-5C14H12O4S
![3-[(4-Bromophenyl)sulfonylmethyl]benzoic acid chemical structure, C14H11BrO4S, CAS 142730-37-8](/s/FMCVXXZZYRXREG-UHFFFAOYSA-N.svg)
3-[(4-Bromophenyl)sulfonylmethyl]benzoic acid
CAS 142730-37-8C14H11BrO4S
![Methyl 3-[(4-bromophenyl)sulfonylmethyl]benzoate chemical structure, C15H13BrO4S, CAS 143427-33-2](/s/VAMJBRHZNIOGGN-UHFFFAOYSA-N.svg)
Methyl 3-[(4-bromophenyl)sulfonylmethyl]benzoate
CAS 143427-33-2C15H13BrO4S
![Methyl 3-[(4-chlorophenyl)sulfonylmethyl]benzoate chemical structure, C15H13ClO4S, CAS 143427-34-3](/s/KSEFSEAXTHHWKL-UHFFFAOYSA-N.svg)
Methyl 3-[(4-chlorophenyl)sulfonylmethyl]benzoate
CAS 143427-34-3C15H13ClO4S
![Ethyl 2-{[3-(ethoxycarbonyl)phenyl]methanesulfonyl}benzoate chemical structure, C19H20O6S, CAS 143427-41-2](/s/WPURPVYLFBBFGM-UHFFFAOYSA-N.svg)
Ethyl 2-{[3-(ethoxycarbonyl)phenyl]methanesulfonyl}benzoate
CAS 143427-41-2C19H20O6S
![Benzoic acid, 4-[[(4-methylphenyl)sulfonyl]methyl]-3-nitro- chemical structure, C15H13NO6S, CAS 103439-96-9](/s/ZDEKGYCDPNHYFW-UHFFFAOYSA-N.svg)
Benzoic acid, 4-[[(4-methylphenyl)sulfonyl]methyl]-3-nitro-
CAS 103439-96-9C15H13NO6S
4-(((4-Bromophenyl)sulfonyl)methyl)-3-nitrobenzoic acid
CAS 103440-00-2C14H10BrNO6S
2-(4-Fluoro-benzenesulfonyl)-2-phenyl-ethylamine
CAS 927990-05-4C14H14FNO2S
![2-[(4-Methoxyphenyl)sulfonyl]-2-phenylethanamine chemical structure, C15H17NO3S, CAS 1094397-37-1](/s/WCTRHGHJSIEORZ-UHFFFAOYSA-N.svg)
2-[(4-Methoxyphenyl)sulfonyl]-2-phenylethanamine
CAS 1094397-37-1C15H17NO3S
![Benzeneethanamine, 3-methoxy-beta-[(4-methylphenyl)sulfonyl]- chemical structure, C16H19NO3S, CAS 927999-48-2](/s/OAIQQBTWAMSIRT-UHFFFAOYSA-N.svg)
Benzeneethanamine, 3-methoxy-beta-[(4-methylphenyl)sulfonyl]-
CAS 927999-48-2C16H19NO3S
![Benzeneethanamine, 3,4-dimethoxy-beta-[(4-methylphenyl)sulfonyl]- chemical structure, C17H21NO4S, CAS 927999-82-4](/s/DLVAPIPEYOQVCH-UHFFFAOYSA-N.svg)
Benzeneethanamine, 3,4-dimethoxy-beta-[(4-methylphenyl)sulfonyl]-
CAS 927999-82-4C17H21NO4S
![Benzeneethanamine, 4-(dimethylamino)-beta-[(4-methylphenyl)sulfonyl]- chemical structure, C17H22N2O2S, CAS 928000-20-8](/s/PZCHXRPWCMNHEF-UHFFFAOYSA-N.svg)
Benzeneethanamine, 4-(dimethylamino)-beta-[(4-methylphenyl)sulfonyl]-
CAS 928000-20-8C17H22N2O2S
n-Boc-alpha-(phenylsulfonyl)-4-methoxybenzylamine
CAS 741259-87-0C19H23NO5S
1-Fluoro-3-(isocyano(tosyl)methyl)benzene
CAS 321345-36-2C15H12FNO2S
![N,N-Dimethyl-4-[(4-methylbenzene-1-sulfonyl)methyl]aniline chemical structure, C16H19NO2S, CAS 33933-62-9](/s/QHVJBWMQBLNFIG-UHFFFAOYSA-N.svg)
N,N-Dimethyl-4-[(4-methylbenzene-1-sulfonyl)methyl]aniline
CAS 33933-62-9C16H19NO2S
![N,N-Dimethyl-4-[(phenylsulfonyl)methyl]benzenamine chemical structure, C15H17NO2S, CAS 13640-68-1](/s/ICWRGOJDJJXKJX-UHFFFAOYSA-N.svg)
N,N-Dimethyl-4-[(phenylsulfonyl)methyl]benzenamine
CAS 13640-68-1C15H17NO2S
![2,4-Dichloro-1-[(phenylsulfonyl)methyl]benzene chemical structure, C13H10Cl2O2S, CAS 90691-46-6](/s/YWZAZLCVWGYEDC-UHFFFAOYSA-N.svg)
2,4-Dichloro-1-[(phenylsulfonyl)methyl]benzene
CAS 90691-46-6C13H10Cl2O2S
![4-[(Phenylmethyl)sulfonyl]phenol chemical structure, C13H12O3S, CAS 769084-02-8](/s/SBPARSMFCCDDFH-UHFFFAOYSA-N.svg)
4-[(Phenylmethyl)sulfonyl]phenol
CAS 769084-02-8C13H12O3S
![2-[(2-Chlorobenzyl)sulfonyl]benzoic acid chemical structure, C14H11ClO4S, CAS 951911-81-2](/s/JWIMQEORJZAZMA-UHFFFAOYSA-N.svg)
2-[(2-Chlorobenzyl)sulfonyl]benzoic acid
CAS 951911-81-2C14H11ClO4S
![2-[(4-Chlorobenzyl)sulfonyl]benzoic acid chemical structure, C14H11ClO4S, CAS 25700-39-4](/s/DBAOINFLAUOXRI-UHFFFAOYSA-N.svg)
2-[(4-Chlorobenzyl)sulfonyl]benzoic acid
CAS 25700-39-4C14H11ClO4S
3-Benzylsulfonyl-5-trifluoromethylbenzoic acid
CAS 28198-30-3C15H11F3O4S
![3-[(Benzenesulfonyl)methyl]aniline chemical structure, C13H13NO2S, CAS 135294-61-0](/s/HBPCCGVNCORBGU-UHFFFAOYSA-N.svg)
3-[(Benzenesulfonyl)methyl]aniline
CAS 135294-61-0C13H13NO2S
1,2-Difluoro-4-(isocyano(tosyl)methyl)benzene
CAS 321345-37-3C15H11F2NO2S
1-(Isocyano(tosyl)methyl)-3-(trifluoromethyl)benzene
CAS 263389-45-3C16H12F3NO2S
- 1-Chloro-3-(isocyano(tosyl)methyl)benzene321345-35-1C15H12ClNO2S
- 1 suppliers1-(Isocyano(tosyl)methyl)-3-methylbenzene459216-21-8C16H15NO2S
- N-((2,5-Difluorophenyl)(tosyl)methyl)formamide668981-00-8C15H13F2NO3S
- 1 suppliers1,4-Difluoro-2-(isocyano(tosyl)methyl)benzene668981-01-9C15H11F2NO2S
- N-((2,4-Difluorophenyl)(tosyl)methyl)formamide668990-82-7C15H13F2NO3S
- 1 suppliers2,4-Difluoro-1-(isocyano(tosyl)methyl)benzene660431-66-3C15H11F2NO2S
- 4-(2,6-Dichlorobenzylsulphonyl)benzylbromide175202-80-9C14H11BrCl2O2S
- [1-(Benzenesulfonyl)-4-chlorobutyl]benzene62089-73-0C16H17ClO2S
- 2-Chloro-1-fluoro-4-(isocyano(tosyl)methyl)benzene811807-51-9C15H11ClFNO2S
- 1-Fluoro-4-[(phenylmethyl)sulfonyl]benzene1512-52-3C13H11FO2S
- 2-[(2-Fluorophenyl)methanesulfonyl]benzoic acid1017027-30-3C14H11FO4S
- 3-(Benzylsulfonyl)-5-nitroaniline912772-83-9C13H12N2O4S
- 4-[(3-Methylphenyl)methanesulfonyl]aniline1082911-15-6C14H15NO2S
- 4-[(4-Methylphenyl)methanesulfonyl]aniline42498-00-0C14H15NO2S
- 4-[(2-Fluorophenyl)methanesulfonyl]aniline1082842-28-1C13H12FNO2S
- 4-[(3-Fluorophenyl)methanesulfonyl]aniline1082911-16-7C13H12FNO2S
- 4-[(4-Fluorophenyl)methanesulfonyl]aniline1082842-29-2C13H12FNO2S
- 4-[(2-Chlorophenyl)methanesulfonyl]aniline1082911-17-8C13H12ClNO2S
- 4-[(3-Chlorophenyl)methanesulfonyl]aniline1082842-30-5C13H12ClNO2S
- 4-[(4-Chlorophenyl)methanesulfonyl]aniline108246-72-6C13H12ClNO2S
- 2-[(3-Cyanophenyl)methanesulfonyl]benzoic acid1036549-48-0C15H11NO4S
- 4-Bromo-2-[(phenylsulfonyl)methyl]aniline945000-74-8C13H12BrNO2S
- 4-(4-Fluorobenzenesulfonylmethyl)-benzoic acid1152564-23-2C14H11FO4S
- 2-Fluoro-5-[[(3-methylphenyl)methyl]sulfonyl]benzoic acid1097007-42-5C15H13FO4S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)c1ccccc11,973 chemicals
O=S(=O)(Nc1ccccc1)c1ccccc1978 chemicals
c1ccc(COc2ccccc2)cc1829 chemicals
c1ccc(N=Nc2ccccc2)cc1383 chemicals
C(=Nc1ccccc1)c1ccccc1379 chemicals
O=C(Oc1ccccc1)c1ccccc1309 chemicals
c1ccc(CNc2ccccc2)cc1309 chemicals
C(=Cc1ccccc1)c1ccccc1279 chemicals
c1ccc(CCc2ccccc2)cc1264 chemicals
O=C(Nc1ccccc1)c1cccnc1140 chemicals
O=C(Cc1ccccc1)c1ccccc1137 chemicals
O=C(Nc1ccccn1)c1ccccc1120 chemicals