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Murcko scaffold

Ring system with 4 rings and 25 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
6
With full pages
5
Scaffold SMILES

O=C(c1ccccc1)c1cn(CCN2CCOCC2)c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)c1cn(CCN2CCOCC2)c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

Pravadoline chemical structure, C23H26N2O3, CAS 92623-83-1
Pravadoline
CAS 92623-83-1C23H26N2O3
AM-630 chemical structure, C23H25IN2O3, CAS 164178-33-0
AM-630
CAS 164178-33-0C23H25IN2O3
(4-Methoxyphenyl)-[1-(2-morpholin-4-ylethyl)indol-3-yl]methanone chemical structure, C22H24N2O3, CAS 103608-67-9
(4-Methoxyphenyl)-[1-(2-morpholin-4-ylethyl)indol-3-yl]methanone
CAS 103608-67-9C22H24N2O3
Win 54,461 chemical structure, C23H25BrN2O3, CAS 166599-63-9
Win 54,461
CAS 166599-63-9C23H25BrN2O3
Pravadoline maleate chemical structure, C27H30N2O7, CAS 92623-84-2
Pravadoline maleate
CAS 92623-84-2C27H30N2O7
4-[2-[3-(4-Methoxybenzoyl)-2-methyl-1H-indol-1-yl]ethyl]-4-methylmorpholinium chemical structure, C24H29N2O3+, CAS 166599-64-0
4-[2-[3-(4-Methoxybenzoyl)-2-methyl-1H-indol-1-yl]ethyl]-4-methylmorpholinium
CAS 166599-64-0C24H29N2O3+