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Murcko scaffold

2(1H)-Quinazolinone, 4-phenyl- scaffold

60 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
60
With full pages
16
Scaffold SMILES

O=c1nc(-c2ccccc2)c2ccccc2[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2(1H)-Quinazolinone, 4-phenyl- page
Murcko scaffold O=c1nc(-c2ccccc2)c2ccccc2[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 60 of 60 chemicals

1-Isopropyl-4-(4-ethyl-phenyl)-6-methoxy-1H-quinazolin-2-one chemical structure, C20H22N2O2, CAS 478963-64-3
1-Isopropyl-4-(4-ethyl-phenyl)-6-methoxy-1H-quinazolin-2-one
CAS 478963-64-3C20H22N2O2
6-Hydroxy-1-isopropyl-4-(4-isopropylphenyl)quinazolin-2(1H)-one chemical structure, C20H22N2O2, CAS 478963-71-2
6-Hydroxy-1-isopropyl-4-(4-isopropylphenyl)quinazolin-2(1H)-one
CAS 478963-71-2C20H22N2O2
2(1H)-Quinazolinone, 1-(1-methylethyl)-4-[4-(1-methylethyl)phenyl]-6-(2-propyn-1-ylamino)- chemical structure, C23H25N3O, CAS 478963-46-1
2(1H)-Quinazolinone, 1-(1-methylethyl)-4-[4-(1-methylethyl)phenyl]-6-(2-propyn-1-ylamino)-
CAS 478963-46-1C23H25N3O
1-Isopropyl-4-(4-isopropylphenyl)-6-methoxyquinazolin-2(1H)-one chemical structure, C21H24N2O2, CAS 478963-62-1
1-Isopropyl-4-(4-isopropylphenyl)-6-methoxyquinazolin-2(1H)-one
CAS 478963-62-1C21H24N2O2
2-(6-Chloro-2-oxo-4-phenyl-1,2-dihydroquinazolin-1-yl)-N-(3-methoxypropyl)acetamide chemical structure, C20H20ClN3O3, CAS 1111296-27-5
2-(6-Chloro-2-oxo-4-phenyl-1,2-dihydroquinazolin-1-yl)-N-(3-methoxypropyl)acetamide
CAS 1111296-27-5C20H20ClN3O3
2-Hydroxy-4-(3-chlorophenyl)quinazoline chemical structure, C14H9ClN2O, CAS 1264037-82-2
2-Hydroxy-4-(3-chlorophenyl)quinazoline
CAS 1264037-82-2C14H9ClN2O
4-(2-Fluorophenyl)-6-nitroquinazolin-2(1H)-one chemical structure, C14H8FN3O3, CAS 88422-40-6
4-(2-Fluorophenyl)-6-nitroquinazolin-2(1H)-one
CAS 88422-40-6C14H8FN3O3
6,7-Dimethoxy-4-(4-methoxyphenyl)quinazolin-2(1H)-one chemical structure, C17H16N2O4, CAS 62499-61-0
6,7-Dimethoxy-4-(4-methoxyphenyl)quinazolin-2(1H)-one
CAS 62499-61-0C17H16N2O4
tert-Butyl 2-oxo-4-phenylquinazoline-1(2H)-carboxylate chemical structure, C19H18N2O3, CAS 1629241-93-5
tert-Butyl 2-oxo-4-phenylquinazoline-1(2H)-carboxylate
CAS 1629241-93-5C19H18N2O3
8-Chloro-5-hydroxy-4-phenylquinazolin-2(1H)-one chemical structure, C14H9ClN2O2, CAS 1206969-27-8
8-Chloro-5-hydroxy-4-phenylquinazolin-2(1H)-one
CAS 1206969-27-8C14H9ClN2O2
6-Chloro-4-(4-methoxyphenyl)-2(1H)-quinazolinone chemical structure, C15H11ClN2O2, CAS 13961-65-4
6-Chloro-4-(4-methoxyphenyl)-2(1H)-quinazolinone
CAS 13961-65-4C15H11ClN2O2
4-(4-Methoxyphenyl)-2(1H)-quinazolinone chemical structure, C15H12N2O2, CAS 22378-46-7
4-(4-Methoxyphenyl)-2(1H)-quinazolinone
CAS 22378-46-7C15H12N2O2