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Murcko scaffold

Ring system with 3 rings and 17 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
10
With full pages
1
Scaffold SMILES

O=c1cnn(-c2ccccc2)c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cnn(-c2ccccc2)c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

1-(4-Chlorophenyl)-4-oxo-5-propoxycinnoline-3-carboxylic acid chemical structure, C18H15ClN2O4, CAS 130561-18-1
1-(4-Chlorophenyl)-4-oxo-5-propoxycinnoline-3-carboxylic acid
CAS 130561-18-1C18H15ClN2O4
3-Cinnolinecarboxylic acid, 1,4-dihydro-4-oxo-1-phenyl- chemical structure, C15H10N2O3, CAS 734-80-5
3-Cinnolinecarboxylic acid, 1,4-dihydro-4-oxo-1-phenyl-
CAS 734-80-5C15H10N2O3
1-(4-Chlorophenyl)-1,4-dihydro-5-methoxy-4-oxo-3-cinnolinecarboxylic acid chemical structure, C16H11ClN2O4, CAS 130560-99-5
1-(4-Chlorophenyl)-1,4-dihydro-5-methoxy-4-oxo-3-cinnolinecarboxylic acid
CAS 130560-99-5C16H11ClN2O4
Methyl 5-chloro-1-(4-chlorophenyl)-4-oxo-1,4-dihydrocinnoline-3-carboxylate chemical structure, C16H10Cl2N2O3, CAS 146743-26-2
Methyl 5-chloro-1-(4-chlorophenyl)-4-oxo-1,4-dihydrocinnoline-3-carboxylate
CAS 146743-26-2C16H10Cl2N2O3
Sintofen chemical structure, C18H15ClN2O5, CAS 130561-48-7
Sintofen
CAS 130561-48-7C18H15ClN2O5
5-Fluoro-4-oxo-1-phenyl-1,4-dihydrocinnoline-3-carboxylic acid chemical structure, C15H9FN2O3, CAS 106815-82-1
5-Fluoro-4-oxo-1-phenyl-1,4-dihydrocinnoline-3-carboxylic acid
CAS 106815-82-1C15H9FN2O3
Ethyl 5-chloro-1-(4-chlorophenyl)-1,4-dihydro-4-oxo-3-cinnolinecarboxylate chemical structure, C17H12Cl2N2O3, CAS 106815-90-1
Ethyl 5-chloro-1-(4-chlorophenyl)-1,4-dihydro-4-oxo-3-cinnolinecarboxylate
CAS 106815-90-1C17H12Cl2N2O3
1-(4-Chlorophenyl)-5-hydroxy-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid chemical structure, C15H9ClN2O4, CAS 160161-66-0
1-(4-Chlorophenyl)-5-hydroxy-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid
CAS 160161-66-0C15H9ClN2O4
1-(4-Chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid chemical structure, C17H13ClN2O5, CAS 160161-65-9
1-(4-Chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid
CAS 160161-65-9C17H13ClN2O5
1-(4-Methylphenyl)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid chemical structure, C16H12N2O3, CAS 1216290-59-3
1-(4-Methylphenyl)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid
CAS 1216290-59-3C16H12N2O3