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Murcko scaffold

Ring system with 2 rings and 12 atoms

42 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 12
Chemicals: 42
With full pages: 19

Scaffold SMILES

C1=CC(c2ccccc2)C=CS1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold C1=CC(c2ccccc2)C=CS1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 42 of 42 chemicals

2,6-Diamino-4-(4-methylphenyl)-4H-thiopyran-3,5-dicarbonitrile chemical structure, C14H12N4S, CAS 127118-56-3

2,6-Diamino-4-(4-methylphenyl)-4H-thiopyran-3,5-dicarbonitrile

CAS 127118-56-3C₁₄H₁₂N₄S

2,6-Diamino-4-(2-iodophenyl)-4H-thiopyran-3,5-dicarbonitrile chemical structure, C13H9IN4S, CAS 202405-54-7

2,6-Diamino-4-(2-iodophenyl)-4H-thiopyran-3,5-dicarbonitrile

CAS 202405-54-7C₁₃H₉IN₄S

2,6-Diamino-4-(2-ethoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile chemical structure, C15H14N4OS, CAS 333759-69-6

2,6-Diamino-4-(2-ethoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile

CAS 333759-69-6C₁₅H₁₄N₄OS

2,6-Diamino-4-(3,4-diethoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile chemical structure, C17H18N4O2S, CAS 330829-11-3

2,6-Diamino-4-(3,4-diethoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile

CAS 330829-11-3C₁₇H₁₈N₄O₂S

2,6-Diamino-4-(2,6-dichlorophenyl)-4H-thiopyran-3,5-dicarbonitrile chemical structure, C13H8Cl2N4S, CAS 333759-84-5

2,6-Diamino-4-(2,6-dichlorophenyl)-4H-thiopyran-3,5-dicarbonitrile

CAS 333759-84-5C₁₃H₈Cl₂N₄S

2,6-Diamino-4-(4-ethoxy-3-methoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile chemical structure, C16H16N4O2S, CAS 311763-22-1

2,6-Diamino-4-(4-ethoxy-3-methoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile

CAS 311763-22-1C₁₆H₁₆N₄O₂S

2,6-Diamino-4-(3,4-dimethoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile chemical structure, C15H14N4O2S, CAS 127118-64-3

2,6-Diamino-4-(3,4-dimethoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile

CAS 127118-64-3C₁₅H₁₄N₄O₂S

2,6-Diamino-4-(2,3-dichlorophenyl)-4H-thiopyran-3,5-dicarbonitrile chemical structure, C13H8Cl2N4S, CAS 311333-38-7

2,6-Diamino-4-(2,3-dichlorophenyl)-4H-thiopyran-3,5-dicarbonitrile

CAS 311333-38-7C₁₃H₈Cl₂N₄S

2,6-Diamino-4-(4-isopropylphenyl)-4H-thiopyran-3,5-dicarbonitrile chemical structure, C16H16N4S, CAS 303066-28-6

2,6-Diamino-4-(4-isopropylphenyl)-4H-thiopyran-3,5-dicarbonitrile

CAS 303066-28-6C₁₆H₁₆N₄S

2,6-Diamino-4-(4-ethoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile chemical structure, C15H14N4OS, CAS 299198-12-2

2,6-Diamino-4-(4-ethoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile

CAS 299198-12-2C₁₅H₁₄N₄OS

2,6-Diamino-4-(4-methoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile chemical structure, C14H12N4OS, CAS 102423-74-5

2,6-Diamino-4-(4-methoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile

CAS 102423-74-5C₁₄H₁₂N₄OS

2,6-Diamino-4-phenyl-4H-thiopyran-3,5-dicarbonitrile chemical structure, C13H10N4S, CAS 102434-73-1

2,6-Diamino-4-phenyl-4H-thiopyran-3,5-dicarbonitrile

CAS 102434-73-1C₁₃H₁₀N₄S

2,6-Diamino-4-(2-methylphenyl)-4H-thiopyran-3,5-dicarbonitrile chemical structure, C14H12N4S, CAS 202405-84-3

2,6-Diamino-4-(2-methylphenyl)-4H-thiopyran-3,5-dicarbonitrile

CAS 202405-84-3C₁₄H₁₂N₄S

2,6-Diamino-4-(4-ethylphenyl)-4H-thiopyran-3,5-dicarbonitrile chemical structure, C15H14N4S, CAS 331986-17-5

2,6-Diamino-4-(4-ethylphenyl)-4H-thiopyran-3,5-dicarbonitrile

CAS 331986-17-5C₁₅H₁₄N₄S

2,6-Diamino-4-(3-chlorophenyl)-4H-thiopyran-3,5-dicarbonitrile chemical structure, C13H9ClN4S, CAS 201807-12-7

2,6-Diamino-4-(3-chlorophenyl)-4H-thiopyran-3,5-dicarbonitrile

CAS 201807-12-7C₁₃H₉ClN₄S

2,6-Diamino-4-(2-methoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile chemical structure, C14H12N4OS, CAS 127118-59-6

2,6-Diamino-4-(2-methoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile

CAS 127118-59-6C₁₄H₁₂N₄OS

2,6-Diamino-4-(2-bromophenyl)-4H-thiopyran-3,5-dicarbonitrile chemical structure, C13H9BrN4S, CAS 333759-76-5

2,6-Diamino-4-(2-bromophenyl)-4H-thiopyran-3,5-dicarbonitrile

CAS 333759-76-5C₁₃H₉BrN₄S

2,6-Diamino-4-(2-fluorophenyl)-4H-thiopyran-3,5-dicarbonitrile chemical structure, C13H9FN4S, CAS 208254-22-2

2,6-Diamino-4-(2-fluorophenyl)-4H-thiopyran-3,5-dicarbonitrile

CAS 208254-22-2C₁₃H₉FN₄S

2,6-Diamino-4-(3-fluorophenyl)-4H-thiopyran-3,5-dicarbonitrile chemical structure, C13H9FN4S, CAS 208254-19-7

2,6-Diamino-4-(3-fluorophenyl)-4H-thiopyran-3,5-dicarbonitrile

CAS 208254-19-7C₁₃H₉FN₄S

2,6-Diamino-4-(2-chlorophenyl)-4H-thiopyran-3,5-dicarbonitrile chemical structure, C13H9ClN4S, CAS 127118-60-9

2,6-Diamino-4-(2-chlorophenyl)-4H-thiopyran-3,5-dicarbonitrile

CAS 127118-60-9C₁₃H₉ClN₄S

2,6-Diamino-4-(2,4-dimethoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile chemical structure, C15H14N4O2S, CAS 127118-62-1

2,6-Diamino-4-(2,4-dimethoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile

CAS 127118-62-1C₁₅H₁₄N₄O₂S

2,6-Diamino-4-(3-methoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile chemical structure, C14H12N4OS, CAS 302904-14-9

2,6-Diamino-4-(3-methoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile

CAS 302904-14-9C₁₄H₁₂N₄OS

2,6-Diamino-4-(4-fluorophenyl)-4H-thiopyran-3,5-dicarbonitrile chemical structure, C13H9FN4S, CAS 125240-16-6

2,6-Diamino-4-(4-fluorophenyl)-4H-thiopyran-3,5-dicarbonitrile

CAS 125240-16-6C₁₃H₉FN₄S

2,6-Diamino-4-(4-bromophenyl)-4H-thiopyran-3,5-dicarbonitrile chemical structure, C13H9BrN4S, CAS 125219-60-5

2,6-Diamino-4-(4-bromophenyl)-4H-thiopyran-3,5-dicarbonitrile

CAS 125219-60-5C₁₃H₉BrN₄S