Murcko scaffold
8-Benzyloxyquinoline scaffold
72 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 18
- Chemicals
- 72
- With full pages
- 8
Scaffold SMILES
c1ccc(COc2cccc3cccnc23)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 72 chemicals
8-Benzyloxyquinoline
CAS 84165-42-4C16H13NO
Quinoline, 8-((2-nitrophenyl)methoxy)-
CAS 82131-87-1C16H12N2O3
![4-Methoxy-3-[(quinolin-8-yloxy)methyl]benzaldehyde chemical structure, C18H15NO3, CAS 438530-70-2](/s/KAIREKLWZOZJFY-UHFFFAOYSA-N.svg)
4-Methoxy-3-[(quinolin-8-yloxy)methyl]benzaldehyde
CAS 438530-70-2C18H15NO3
8-(Benzyloxy)-2-methylquinoline
CAS 93315-49-2C17H15NO
8-(Benzyloxy)quinoline-2-carbaldehyde
CAS 88238-73-7C17H13NO2
8-(Benzyloxy)-5,7-dibromoquinoline
CAS 84165-50-4C16H11Br2NO
![4-[(Quinolin-8-yloxy)methyl]benzohydrazide chemical structure, C17H15N3O2, CAS 380348-54-9](/s/GZEPGQARAYQUPR-UHFFFAOYSA-N.svg)
4-[(Quinolin-8-yloxy)methyl]benzohydrazide
CAS 380348-54-9C17H15N3O2
4-(Quinolin-8-yloxymethyl)benzonitrile
CAS 734543-82-9C17H12N2O
Quinoline, 5-bromo-8-(phenylmethoxy)-
CAS 202259-06-1C16H12BrNO
![[(E)-(8-Phenylmethoxyquinolin-2-yl)methylideneamino]urea chemical structure, C18H16N4O2, CAS 536718-26-0](/s/GULRWVMNHIEFJS-RGVLZGJSSA-N.svg)
[(E)-(8-Phenylmethoxyquinolin-2-yl)methylideneamino]urea
CAS 536718-26-0C18H16N4O2
8-(Benzyloxy)quinolin-2-amine
CAS 343787-14-4C16H14N2O
8-(Benzyloxy)quinoline-5-carbaldehyde
CAS 200285-24-1C17H13NO2
![2-Methyl-8-[(2-methyl-3-nitrophenyl)methoxy]quinoline chemical structure, C18H16N2O3, CAS 179626-02-9](/s/QMDTXWRBNMIIMQ-UHFFFAOYSA-N.svg)
2-Methyl-8-[(2-methyl-3-nitrophenyl)methoxy]quinoline
CAS 179626-02-9C18H16N2O3
8-(2,6-Dichloro-3-nitrobenzyloxy)-2-methylquinoline
CAS 167834-56-2C17H12Cl2N2O3
![8-[2,6-Dichloro-3-glycylaminobenzyloxy]-2-methylquinoline chemical structure, C19H17Cl2N3O2, CAS 179621-82-0](/s/NNNYDOYTZCKQPV-UHFFFAOYSA-N.svg)
8-[2,6-Dichloro-3-glycylaminobenzyloxy]-2-methylquinoline
CAS 179621-82-0C19H17Cl2N3O2
![2-Methyl-3-[(2-methylquinolin-8-yl)oxymethyl]aniline chemical structure, C18H18N2O, CAS 179626-03-0](/s/NKIYWQXHGLYLIA-UHFFFAOYSA-N.svg)
2-Methyl-3-[(2-methylquinolin-8-yl)oxymethyl]aniline
CAS 179626-03-0C18H18N2O
8-(3-Amino-2,6-dichlorobenzyloxy)-2-methylquinoline
CAS 179625-53-7C17H14Cl2N2O
![4-Chloro-3-[(2-methylquinolin-8-yl)oxymethyl]aniline chemical structure, C17H15ClN2O, CAS 179625-66-2](/s/BRFUUPGEUVCNCX-UHFFFAOYSA-N.svg)
4-Chloro-3-[(2-methylquinolin-8-yl)oxymethyl]aniline
CAS 179625-66-2C17H15ClN2O
8-(Benzyloxy)quinolin-5-amine
CAS 213027-68-0C16H14N2O
5-Acetyl-8-(phenylmethoxy)quinoline
CAS 26872-48-0C18H15NO2
5-Acetyl-8-(phenylmethoxy)-2-quinoline N-Oxide
CAS 100331-93-9C18H15NO3
(8-(Benzyloxy)quinolin-5-yl)methanol
CAS 108835-25-2C17H15NO2
![8-[(3-Fluoro-4-methoxyphenyl)methoxy]-2-methylquinoline chemical structure, C18H16FNO2, CAS 878957-70-1](/s/NMOSAMFDAQDOCR-UHFFFAOYSA-N.svg)
8-[(3-Fluoro-4-methoxyphenyl)methoxy]-2-methylquinoline
CAS 878957-70-1C18H16FNO2
8-(Benzyloxy)-5-chloroquinoline
CAS 1067179-23-0C16H12ClNO
- 8-(2,6-Dichloro-3-methylaminobenzyloxy)-2-methylquinoline179625-51-5C18H16Cl2N2O
- 8-Benzyloxy-4-ethoxycarbonylmethoxy-2-methylquinoline179626-84-7C21H21NO4
- 8-(Benzyloxy)-2-chloroquinoline343788-51-2C16H12ClNO
- 8-[(3-Bromo-2,6-dimethylphenyl)methoxy]-2-methylquinoline597543-18-5C19H18BrNO
- 4-[[(2-Methyl-8-quinolinyl)oxy]methyl]benzoic acid477585-42-5C18H15NO3
- 2-Methoxy-6-(quinolin-8-yloxymethyl)-benzoic acid ethyl ester1171924-37-0C20H19NO4
- 2-Methoxy-6-(quinolin-8-yloxymethyl)-benzoic acid methyl ester1171924-46-1C19H17NO4
- 2-Methoxy-6-(quinolin-8-yloxymethyl)-benzoic acid1171924-48-3C18H15NO4
- 5,7-Dichloro-8-benzyloxy-quinoline-2-carboxylic acid24010-10-4C17H11Cl2NO3
- 3-[8-(Phenylmethoxy)-7-quinolinyl]-1,2-propanediol1009842-69-6C19H19NO3
- 7-Allyl-8-(benzyloxy)-5-chloroquinoline1009842-68-5C19H16ClNO
- 8-(Benzyloxy)quinoline-5-sulfonyl chloride1342646-77-8C16H12ClNO3S
- 8-(Benzyloxy)quinoline-5-sulfonamide1340220-07-6C16H14N2O3S
- 2-Phenyl-2-(quinolin-8-yloxy)-ethylamine886765-93-1C17H16N2O
- 8-[(2,6-Dichlorophenyl)methoxy]quinoline82131-92-8C16H11Cl2NO
- 8-(Benzyloxy)-4-chloro-2-methylquinoline1360587-86-5C17H14ClNO
- 8-Benzyloxy-2-methoxyquinoline-5-carboxylic acid methyl ester1037124-23-4C19H17NO4
- 8-Benzyloxy-2-methoxyquinoline-5-carboxylic acid885688-15-3C18H15NO4
- 8-(Benzyloxy)-2-methoxyquinoline642477-85-8C17H15NO2
- 8-Benzyloxy-5-bromo-2-methoxyquinoline885687-77-4C17H14BrNO2
- 2-Methyl-8-(4-(trifluoromethyl)benzyloxy)quinoline1383949-10-7C18H14F3NO
- 8-(Benzyloxy)quinoline-7-carboxylic acid630414-70-9C17H13NO3
- 8-Benzyloxy-7-fluoro-2-methoxy-quinoline1184302-56-4C17H14FNO2
- 1-(5-Chloro-8-phenylmethoxyquinolin-7-yl)ethanamine1004980-14-6C18H17ClN2O
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(N=Nc2cccc3ccccc23)cc1153 chemicals
c1ccc(CNc2ncnc3ccccc23)cc140 chemicals
C(=Nc1ccccc1)c1cccc2ccccc1236 chemicals
O=C(Nc1ccccc1)c1cccc2ccccc1235 chemicals
O=S(=O)(Nc1cccc2ccccc12)c1ccccc129 chemicals
O=C(Nc1cccc2cccnc12)c1ccccc127 chemicals
O=C(Nc1cccc2ccccc12)c1ccccc121 chemicals
O=C(NC1CCCc2ccccc21)c1ccccc120 chemicals
C(=Nc1cccc2ccccc12)c1ccccc118 chemicals
O=C(Nc1cccc2ncccc12)c1ccccc118 chemicals
O=C(Nc1ccccc1)c1ccnc2ccccc1216 chemicals
O=S(=O)(Nc1cccc2cccnc12)c1ccccc115 chemicals