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Murcko scaffold

1-(Azetidin-3-yl)pyrrolidin-2-one scaffold

91 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
91
With full pages
5
Scaffold SMILES

O=C1CCCN1C1CNC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(Azetidin-3-yl)pyrrolidin-2-one page
Murcko scaffold O=C1CCCN1C1CNC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 91 chemicals

tert-Butyl 3-(2-oxopyrrolidin-1-yl)azetidine-1-carboxylate chemical structure, C12H20N2O3, CAS 1257294-07-7
tert-Butyl 3-(2-oxopyrrolidin-1-yl)azetidine-1-carboxylate
CAS 1257294-07-7C12H20N2O3
1-(Azetidin-3-yl)pyrrolidin-2-one chemical structure, C7H12N2O, CAS 1257294-05-5
1-(Azetidin-3-yl)pyrrolidin-2-one
CAS 1257294-05-5C7H12N2O
1-(Azetidin-3-yl)pyrrolidin-2-one hydrochloride chemical structure, C7H13ClN2O, CAS 1403766-91-5
1-(Azetidin-3-yl)pyrrolidin-2-one hydrochloride
CAS 1403766-91-5C7H13ClN2O
1-(Azetidin-3-yl)-5-oxopyrrolidine-3-carboxylic acid chemical structure, C8H12N2O3, CAS 1554204-05-5
1-(Azetidin-3-yl)-5-oxopyrrolidine-3-carboxylic acid
CAS 1554204-05-5C8H12N2O3
Methyl 1-(azetidin-3-yl)-5-oxopyrrolidine-3-carboxylate chemical structure, C9H14N2O3, CAS 1784138-24-4
Methyl 1-(azetidin-3-yl)-5-oxopyrrolidine-3-carboxylate
CAS 1784138-24-4C9H14N2O3
1-(Azetidin-3-yl)pyrrolidin-2-one, tfa salt chemical structure, C9H13F3N2O3, CAS 1706436-80-7
1-(Azetidin-3-yl)pyrrolidin-2-one, tfa salt
CAS 1706436-80-7C9H13F3N2O3
1-(1-Methylazetidin-3-yl)-5-oxopyrrolidine-3-carboxylic acid chemical structure, C9H14N2O3, CAS 1881756-67-7
1-(1-Methylazetidin-3-yl)-5-oxopyrrolidine-3-carboxylic acid
CAS 1881756-67-7C9H14N2O3
1-{1-[(tert-Butoxy)carbonyl]azetidin-3-yl}-5-oxopyrrolidine-3-carboxylic acid chemical structure, C13H20N2O5, CAS 2138132-27-9
1-{1-[(tert-Butoxy)carbonyl]azetidin-3-yl}-5-oxopyrrolidine-3-carboxylic acid
CAS 2138132-27-9C13H20N2O5
1-(Azetidin-3-yl)-N,N-dimethyl-5-oxopyrrolidine-3-carboxamide hydrochloride chemical structure, C10H18ClN3O2, CAS 2138194-41-7
1-(Azetidin-3-yl)-N,N-dimethyl-5-oxopyrrolidine-3-carboxamide hydrochloride
CAS 2138194-41-7C10H18ClN3O2
1-(Azetidin-3-yl)-N,N-dimethyl-5-oxopyrrolidine-3-carboxamide chemical structure, C10H17N3O2, CAS 2137535-64-7
1-(Azetidin-3-yl)-N,N-dimethyl-5-oxopyrrolidine-3-carboxamide
CAS 2137535-64-7C10H17N3O2
tert-Butyl 3-(4-amino-2-oxopyrrolidin-1-yl)azetidine-1-carboxylate chemical structure, C12H21N3O3, CAS 2138423-52-4
tert-Butyl 3-(4-amino-2-oxopyrrolidin-1-yl)azetidine-1-carboxylate
CAS 2138423-52-4C12H21N3O3
1-[1-(But-2-ynoyl)azetidin-3-yl]-N-methyl-5-oxopyrrolidine-3-carboxamide chemical structure, C13H17N3O3, CAS 2190740-74-8
1-[1-(But-2-ynoyl)azetidin-3-yl]-N-methyl-5-oxopyrrolidine-3-carboxamide
CAS 2190740-74-8C13H17N3O3
1-(Azetidin-3-yl)-N-methyl-5-oxopyrrolidine-3-carboxamide, trifluoroacetic acid chemical structure, C11H16F3N3O4, CAS 2187435-22-7
1-(Azetidin-3-yl)-N-methyl-5-oxopyrrolidine-3-carboxamide, trifluoroacetic acid
CAS 2187435-22-7C11H16F3N3O4
1-(Azetidin-3-yl)-N-methyl-5-oxopyrrolidine-3-carboxamide chemical structure, C9H15N3O2, CAS 2126163-34-4
1-(Azetidin-3-yl)-N-methyl-5-oxopyrrolidine-3-carboxamide
CAS 2126163-34-4C9H15N3O2
Lithium(1+) ion 1-(1-methylazetidin-3-yl)-5-oxopyrrolidine-3-carboxylate chemical structure, C9H13LiN2O3, CAS 2172251-24-8
Lithium(1+) ion 1-(1-methylazetidin-3-yl)-5-oxopyrrolidine-3-carboxylate
CAS 2172251-24-8C9H13LiN2O3
1-[1-(Prop-2-enoyl)azetidin-3-yl]pyrrolidin-2-one chemical structure, C10H14N2O2, CAS 2224358-62-5
1-[1-(Prop-2-enoyl)azetidin-3-yl]pyrrolidin-2-one
CAS 2224358-62-5C10H14N2O2
tert-Butyl 3-(3-amino-2-oxopyrrolidin-1-yl)azetidine-1-carboxylate chemical structure, C12H21N3O3, CAS 2305253-99-8
tert-Butyl 3-(3-amino-2-oxopyrrolidin-1-yl)azetidine-1-carboxylate
CAS 2305253-99-8C12H21N3O3
Methyl 1-(azetidin-3-yl)-5-oxopyrrolidine-3-carboxylate hydrochloride chemical structure, C9H15ClN2O3, CAS 2361634-21-9
Methyl 1-(azetidin-3-yl)-5-oxopyrrolidine-3-carboxylate hydrochloride
CAS 2361634-21-9C9H15ClN2O3
1-(Azetidin-3-yl)-5-oxopyrrolidine-3-carboxylic acid, trifluoroacetic acid chemical structure, C10H13F3N2O5, CAS 2375261-05-3
1-(Azetidin-3-yl)-5-oxopyrrolidine-3-carboxylic acid, trifluoroacetic acid
CAS 2375261-05-3C10H13F3N2O5
tert-Butyl 3-[2-oxo-4-(prop-2-enamido)pyrrolidin-1-yl]azetidine-1-carboxylate chemical structure, C15H23N3O4, CAS 2411261-64-6
tert-Butyl 3-[2-oxo-4-(prop-2-enamido)pyrrolidin-1-yl]azetidine-1-carboxylate
CAS 2411261-64-6C15H23N3O4
1-(1-Carbamoylazetidin-3-yl)-N,N-dimethyl-5-oxopyrrolidine-3-carboxamide chemical structure, C11H18N4O3, CAS 2408957-66-2
1-(1-Carbamoylazetidin-3-yl)-N,N-dimethyl-5-oxopyrrolidine-3-carboxamide
CAS 2408957-66-2C11H18N4O3
tert-Butyl 3-{4-[(2E)-4-(dimethylamino)but-2-enamido]-2-oxopyrrolidin-1-yl}azetidine-1-carboxylate chemical structure, C18H30N4O4, CAS 2411332-07-3
tert-Butyl 3-{4-[(2E)-4-(dimethylamino)but-2-enamido]-2-oxopyrrolidin-1-yl}azetidine-1-carboxylate
CAS 2411332-07-3C18H30N4O4
tert-Butyl 3-[4-(2-chloroacetamido)-2-oxopyrrolidin-1-yl]azetidine-1-carboxylate chemical structure, C14H22ClN3O4, CAS 2411263-75-5
tert-Butyl 3-[4-(2-chloroacetamido)-2-oxopyrrolidin-1-yl]azetidine-1-carboxylate
CAS 2411263-75-5C14H22ClN3O4
tert-Butyl 3-[4-(but-2-ynamido)-2-oxopyrrolidin-1-yl]azetidine-1-carboxylate chemical structure, C16H23N3O4, CAS 2411259-91-9
tert-Butyl 3-[4-(but-2-ynamido)-2-oxopyrrolidin-1-yl]azetidine-1-carboxylate
CAS 2411259-91-9C16H23N3O4