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Murcko scaffold

Ring system with 3 rings and 29 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
29
Chemicals
9
With full pages
2
Scaffold SMILES

O=C(COC(=O)C(CC(=O)c1ccccc1)Nc1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COC(=O)C(CC(=O)c1ccccc1)Nc1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

2-(4-Methylphenyl)-2-oxoethyl 2-[(2-methoxyphenyl)amino]-4-oxo-4-phenylbutanoate chemical structure, C26H25NO5, CAS 1025759-34-5
2-(4-Methylphenyl)-2-oxoethyl 2-[(2-methoxyphenyl)amino]-4-oxo-4-phenylbutanoate
CAS 1025759-34-5C26H25NO5
[2-(3-Methoxyphenyl)-2-oxoethyl] 2-(2,3-dichloroanilino)-4-oxo-4-phenylbutanoate chemical structure, C25H21Cl2NO5, CAS 1025759-37-8
[2-(3-Methoxyphenyl)-2-oxoethyl] 2-(2,3-dichloroanilino)-4-oxo-4-phenylbutanoate
CAS 1025759-37-8C25H21Cl2NO5
2-(4-Fluorophenyl)-2-oxoethyl 2-[(2,5-dichlorophenyl)amino]-4-oxo-4-phenylbutanoate chemical structure, C24H18Cl2FNO4, CAS 1042693-34-4
2-(4-Fluorophenyl)-2-oxoethyl 2-[(2,5-dichlorophenyl)amino]-4-oxo-4-phenylbutanoate
CAS 1042693-34-4C24H18Cl2FNO4
2-(3-Methoxyphenyl)-2-oxoethyl 2-((2,4-dimethylphenyl)amino)-4-oxo-4-phenylbutanoate chemical structure, C27H27NO5, CAS 1093642-26-2
2-(3-Methoxyphenyl)-2-oxoethyl 2-((2,4-dimethylphenyl)amino)-4-oxo-4-phenylbutanoate
CAS 1093642-26-2C27H27NO5
2-(4-Bromophenyl)-2-oxoethyl 2-[(2-methoxyphenyl)amino]-4-oxo-4-phenylbutanoate chemical structure, C25H22BrNO5, CAS 1025759-47-0
2-(4-Bromophenyl)-2-oxoethyl 2-[(2-methoxyphenyl)amino]-4-oxo-4-phenylbutanoate
CAS 1025759-47-0C25H22BrNO5
[2-(4-Methylphenyl)-2-oxoethyl] 2-(4-fluoroanilino)-4-oxo-4-phenylbutanoate chemical structure, C25H22FNO4, CAS 1008003-09-5
[2-(4-Methylphenyl)-2-oxoethyl] 2-(4-fluoroanilino)-4-oxo-4-phenylbutanoate
CAS 1008003-09-5C25H22FNO4
[2-(3-Nitrophenyl)-2-oxoethyl] 2-(4-chloroanilino)-4-oxo-4-phenylbutanoate chemical structure, C24H19ClN2O6, CAS 1025725-35-2
[2-(3-Nitrophenyl)-2-oxoethyl] 2-(4-chloroanilino)-4-oxo-4-phenylbutanoate
CAS 1025725-35-2C24H19ClN2O6
2-(4-Bromophenyl)-2-oxoethyl 2-[(4-fluorophenyl)amino]-4-oxo-4-phenylbutanoate chemical structure, C24H19BrFNO4, CAS 1093814-18-6
2-(4-Bromophenyl)-2-oxoethyl 2-[(4-fluorophenyl)amino]-4-oxo-4-phenylbutanoate
CAS 1093814-18-6C24H19BrFNO4
2-(3-Methoxyphenyl)-2-oxoethyl 2-[(2,4-dichlorophenyl)amino]-4-oxo-4-phenylbutanoate chemical structure, C25H21Cl2NO5, CAS 1022918-39-3
2-(3-Methoxyphenyl)-2-oxoethyl 2-[(2,4-dichlorophenyl)amino]-4-oxo-4-phenylbutanoate
CAS 1022918-39-3C25H21Cl2NO5