Murcko scaffold
N-Cyclobutylaniline scaffold
425 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 11
- Chemicals
- 425
- With full pages
- 12
Scaffold SMILES
c1ccc(NC2CCC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 289 to 336 of 425 chemicals
![4-{[trans-2-Hydroxycyclobutyl]amino}phenol chemical structure, C10H13NO2, CAS 2165483-13-4](/s/ALJRQJIJURCJKL-NXEZZACHSA-N.svg)
4-{[trans-2-Hydroxycyclobutyl]amino}phenol
CAS 2165483-13-4C10H13NO2
![trans-2-[(2-Hydroxyethyl)(phenyl)amino]cyclobutan-1-ol chemical structure, C12H17NO2, CAS 2150888-52-9](/s/GJNUYFJMAQHNMF-VXGBXAGGSA-N.svg)
trans-2-[(2-Hydroxyethyl)(phenyl)amino]cyclobutan-1-ol
CAS 2150888-52-9C12H17NO2
![trans-2-[(2-Methoxy-5-methylphenyl)amino]cyclobutan-1-ol chemical structure, C12H17NO2, CAS 2165940-53-2](/s/MVNJUYRZLQVCKK-MWLCHTKSSA-N.svg)
trans-2-[(2-Methoxy-5-methylphenyl)amino]cyclobutan-1-ol
CAS 2165940-53-2C12H17NO2
![trans-2-[(3,5-Dimethylphenyl)amino]cyclobutan-1-ol chemical structure, C12H17NO, CAS 2165536-47-8](/s/QBSKZMSGKOVLCQ-VXGBXAGGSA-N.svg)
trans-2-[(3,5-Dimethylphenyl)amino]cyclobutan-1-ol
CAS 2165536-47-8C12H17NO
![trans-2-[(3-Methylphenyl)amino]cyclobutan-1-ol chemical structure, C11H15NO, CAS 2165518-55-6](/s/YSHJHMRJXXAFJL-GHMZBOCLSA-N.svg)
trans-2-[(3-Methylphenyl)amino]cyclobutan-1-ol
CAS 2165518-55-6C11H15NO
![trans-2-[(3-Chlorophenyl)amino]cyclobutan-1-ol chemical structure, C10H12ClNO, CAS 2150220-57-6](/s/DWENPKZECXWRCE-NXEZZACHSA-N.svg)
trans-2-[(3-Chlorophenyl)amino]cyclobutan-1-ol
CAS 2150220-57-6C10H12ClNO
![trans-2-[(4-Methylphenyl)amino]cyclobutan-1-ol chemical structure, C11H15NO, CAS 2147925-13-9](/s/UZVSNIYESOZXFB-GHMZBOCLSA-N.svg)
trans-2-[(4-Methylphenyl)amino]cyclobutan-1-ol
CAS 2147925-13-9C11H15NO
![trans-2-[(4-Chlorophenyl)amino]cyclobutan-1-ol chemical structure, C10H12ClNO, CAS 2149368-10-3](/s/DGTNEBOCYRZFRH-NXEZZACHSA-N.svg)
trans-2-[(4-Chlorophenyl)amino]cyclobutan-1-ol
CAS 2149368-10-3C10H12ClNO
![trans-2-[(4-Methoxyphenyl)amino]cyclobutan-1-ol chemical structure, C11H15NO2, CAS 2149520-92-1](/s/MUMGCKOGWSYOCK-GHMZBOCLSA-N.svg)
trans-2-[(4-Methoxyphenyl)amino]cyclobutan-1-ol
CAS 2149520-92-1C11H15NO2
![trans-2-{[4-(2-Hydroxyethyl)phenyl]amino}cyclobutan-1-ol chemical structure, C12H17NO2, CAS 2166005-82-7](/s/TUEJODXPKOSDDP-VXGBXAGGSA-N.svg)
trans-2-{[4-(2-Hydroxyethyl)phenyl]amino}cyclobutan-1-ol
CAS 2166005-82-7C12H17NO2
![trans-2-[Ethyl(phenyl)amino]cyclobutan-1-ol chemical structure, C12H17NO, CAS 2165939-75-1](/s/HKBAKJGXNWRPCK-VXGBXAGGSA-N.svg)
trans-2-[Ethyl(phenyl)amino]cyclobutan-1-ol
CAS 2165939-75-1C12H17NO
![trans-2-[(4-Methoxy-2-methylphenyl)amino]cyclobutan-1-ol chemical structure, C12H17NO2, CAS 2158287-07-9](/s/YFCYJYIAGNHZFZ-VXGBXAGGSA-N.svg)
trans-2-[(4-Methoxy-2-methylphenyl)amino]cyclobutan-1-ol
CAS 2158287-07-9C12H17NO2
4-Bromo-N-cyclobutyl-3,5-difluoroaniline
CAS 2015528-01-3C10H10BrF2N
3-Bromo-5-cyclobutylamino-N-ethylbenzamide
CAS 2270912-34-8C13H17BrN2O
Methyl 3-bromo-5-(cyclobutylamino)benzoate
CAS 2270912-06-4C12H14BrNO2
N-Cyclobutyl-4,5-difluoro-2-nitroaniline
CAS 1872401-09-6C10H10F2N2O2
![Methyl 1-[3-fluoro-4-(methylcarbamoyl)anilino]cyclobutane-1-carboxylate chemical structure, C14H17FN2O3, CAS 2227589-23-1](/s/SMHKDLVTHWNASR-UHFFFAOYSA-N.svg)
Methyl 1-[3-fluoro-4-(methylcarbamoyl)anilino]cyclobutane-1-carboxylate
CAS 2227589-23-1C14H17FN2O3
Methyl 5-bromo-3-(cyclobutylamino)-2-methylbenzoate
CAS 2270910-61-5C13H16BrNO2
![1-[2-(Cyclobutylamino)-5-nitrophenyl]ethanone chemical structure, C12H14N2O3, CAS 2222512-27-6](/s/KDJQYOOQXFSQDX-UHFFFAOYSA-N.svg)
1-[2-(Cyclobutylamino)-5-nitrophenyl]ethanone
CAS 2222512-27-6C12H14N2O3
amino}benzoic acid chemical structure, C16H21NO4, CAS 2248311-38-6](/s/JJVLEFXPNOCTON-UHFFFAOYSA-N.svg)
2-{[(tert-Butoxy)carbonyl](cyclobutyl)amino}benzoic acid
CAS 2248311-38-6C16H21NO4
tert-Butyl 2-(cyclobutylamino)benzoate
CAS 2248417-70-9C15H21NO2
2-Bromo-N-cyclobutylaniline hydrochloride
CAS 2225136-23-0C10H13BrClN
N-Cyclobutyl-4-fluoroaniline hydrochloride
CAS 2228694-06-0C10H13ClFN
![4-{[trans-2-Hydroxycyclobutyl]amino}benzonitrile chemical structure, C11H12N2O, CAS 2413365-20-3](/s/OJPLMXOSBJGJER-QWRGUYRKSA-N.svg)
4-{[trans-2-Hydroxycyclobutyl]amino}benzonitrile
CAS 2413365-20-3C11H12N2O
- N-(2-Cyanophenyl)-N-cyclobutylprop-2-enamide2361640-50-6C14H14N2O
- 3-(tert-Butyl)-N-cyclobutylaniline2566172-70-9C14H21N
- 4-Bromo-N1-cyclobutyl-3-methylbenzene-1,2-diamine2563282-40-4C11H15BrN2
- Methyl 4-(cyclobutylamino)-3-fluorobenzoate1563216-16-9C12H14FNO2
- 4-(2-Cyano-cyclobutylamino)-2-fluoro-N-methyl-benzamide2108996-77-4C13H14FN3O
- 3-Chloro-N-cyclobutyl-4-(trifluoromethoxy)aniline2752228-79-6C11H11ClF3NO
- N-Cyclobutyl-2-iodoaniline hydrochloride2378501-91-6C10H13ClIN
- N-Cyclobutyl-4-fluoro-2-iodoaniline hydrochloride2378503-75-2C10H12ClFIN
- N-Cyclobutyl-2-iodo-4-(trifluoromethyl)aniline2749921-54-6C11H11F3IN
- N-Cyclobutyl-2-iodo-4-methylaniline2742072-81-5C11H14IN
- (2-Bromo-5-trifluoromethoxyphenyl)-cyclobutylamine2742306-86-9C11H11BrF3NO
- 2-Bromo-N-cyclobutyl-4-(trifluoromethoxy)aniline2751267-76-0C11H11BrF3NO
- 5-Bromo-N-cyclobutyl-2-(trifluoromethoxy)aniline2749755-22-2C11H11BrF3NO
- 5-Bromo-4-(cyclobutylamino)-2-(trifluoromethyl)benzonitrile2752776-89-7C12H10BrF3N2
- 2-Chloro-N-(3-cyanophenyl)-N-cyclobutylpropanamide2411284-29-0C14H15ClN2O
- 2-Chloro-N-(4-cyanophenyl)-N-cyclobutylpropanamide2411262-98-9C14H15ClN2O
- N-Cyclobutyl-3-methoxy-4-methylaniline1999873-93-6C12H17NO
- Methyl 3-Carbamoyl-3-[(4-iodophenyl)amino]cyclobutane-1-carboxylate2330881-40-6C13H15IN2O3
- Methyl 3-cyano-3-((4-iodophenyl)amino)cyclobutanecarboxylate2330881-37-1C13H13IN2O2
- Rel-(1R,2R)-2-((3,4-dimethoxyphenyl)amino)cyclobutan-1-ol2156416-22-5C12H17NO3
- Rel-(1R,2R)-2-((2-(trifluoromethyl)phenyl)amino)cyclobutan-1-ol2151265-15-3C11H12F3NO
- Rel-(1R,2R)-2-((2,3,4-trifluorophenyl)amino)cyclobutan-1-ol2165115-11-5C10H10F3NO
- Rel-3-(((1R,2R)-2-hydroxycyclobutyl)amino)benzonitrile2158893-76-4C11H12N2O
- (4-(Cyclobutylamino)-3-nitrophenyl)methanol1866904-84-8C11H14N2O3
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(CC2CCC2)cc148 chemicals
c1ccc(CC2CNC2)cc141 chemicals
c1ccc(OC2CNC2)cc131 chemicals
c1ccc(CN2CCC2)cc115 chemicals
c1ccc(NC2COC2)cc114 chemicals
c1ccc(OC2CCC2)cc112 chemicals
c1ccc(OC2COC2)cc110 chemicals
c1ccc(CC2COC2)cc18 chemicals
O=S(=O)(c1ccccc1)N1CCC18 chemicals
c1ccc(OC2CCC2)nc18 chemicals
C(=C1CNC1)c1ccccc16 chemicals
c1ccc(NC2CNC2)cc15 chemicals