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Murcko scaffold

Ring system with 2 rings and 17 atoms

443 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
443
With full pages
77
Scaffold SMILES

O=C(CSc1ccccc1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1ccccc1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 337 to 384 of 443 chemicals

2-[(3-Methylphenyl)sulfanyl]-N-(2-nitrophenyl)acetamide chemical structure, C15H14N2O3S, CAS 331460-40-3
2-[(3-Methylphenyl)sulfanyl]-N-(2-nitrophenyl)acetamide
CAS 331460-40-3C15H14N2O3S
2-[(4-Fluorophenyl)sulfanyl]-N-[4-(trifluoromethoxy)phenyl]acetamide chemical structure, C15H11F4NO2S, CAS 329779-76-2
2-[(4-Fluorophenyl)sulfanyl]-N-[4-(trifluoromethoxy)phenyl]acetamide
CAS 329779-76-2C15H11F4NO2S
N-(2,3-Dichlorophenyl)-2-[(3-methylphenyl)sulfanyl]acetamide chemical structure, C15H13Cl2NOS, CAS 882079-96-1
N-(2,3-Dichlorophenyl)-2-[(3-methylphenyl)sulfanyl]acetamide
CAS 882079-96-1C15H13Cl2NOS
N-(4-Methoxy-2-nitrophenyl)-2-[(4-methylphenyl)sulfanyl]acetamide chemical structure, C16H16N2O4S, CAS 331461-12-2
N-(4-Methoxy-2-nitrophenyl)-2-[(4-methylphenyl)sulfanyl]acetamide
CAS 331461-12-2C16H16N2O4S
N-(3-Chloro-4-fluorophenyl)-2-[(2,3,4,5,6-pentafluorophenyl)sulfanyl]acetamide chemical structure, C14H6ClF6NOS, CAS 883794-61-4
N-(3-Chloro-4-fluorophenyl)-2-[(2,3,4,5,6-pentafluorophenyl)sulfanyl]acetamide
CAS 883794-61-4C14H6ClF6NOS
2-[2-(4-Chlorophenyl)sulfanylpropanoylamino]-3,5-dimethylbenzoic acid chemical structure, C18H18ClNO3S, CAS 1023576-89-7
2-[2-(4-Chlorophenyl)sulfanylpropanoylamino]-3,5-dimethylbenzoic acid
CAS 1023576-89-7C18H18ClNO3S
N-(4-Ethoxyphenyl)-2-[(3-methylphenyl)sulfanyl]acetamide chemical structure, C17H19NO2S, CAS 329079-29-0
N-(4-Ethoxyphenyl)-2-[(3-methylphenyl)sulfanyl]acetamide
CAS 329079-29-0C17H19NO2S
2-((4-Aminophenyl)thio)-N-(3,4-dimethylphenyl)acetamide chemical structure, C16H18N2OS, CAS 763130-03-6
2-((4-Aminophenyl)thio)-N-(3,4-dimethylphenyl)acetamide
CAS 763130-03-6C16H18N2OS
N-(3,4-Difluorophenyl)-2-[(4-fluorophenyl)sulfanyl]acetamide chemical structure, C14H10F3NOS, CAS 329779-75-1
N-(3,4-Difluorophenyl)-2-[(4-fluorophenyl)sulfanyl]acetamide
CAS 329779-75-1C14H10F3NOS
2-[({[4-(Methoxycarbonyl)phenyl]carbamoyl}methyl)sulfanyl]benzoic acid chemical structure, C17H15NO5S, CAS 326015-91-2
2-[({[4-(Methoxycarbonyl)phenyl]carbamoyl}methyl)sulfanyl]benzoic acid
CAS 326015-91-2C17H15NO5S
N-(2,4-Difluorophenyl)-2-((perfluorophenyl)thio)acetamide chemical structure, C14H6F7NOS, CAS 477320-63-1
N-(2,4-Difluorophenyl)-2-((perfluorophenyl)thio)acetamide
CAS 477320-63-1C14H6F7NOS
2-[(4-Methylphenyl)sulfanyl]-N-[4-(trifluoromethyl)phenyl]acetamide chemical structure, C16H14F3NOS, CAS 755015-57-7
2-[(4-Methylphenyl)sulfanyl]-N-[4-(trifluoromethyl)phenyl]acetamide
CAS 755015-57-7C16H14F3NOS
N-(4-Butylphenyl)-2-[(4-fluorophenyl)sulfanyl]acetamide chemical structure, C18H20FNOS, CAS 303091-24-9
N-(4-Butylphenyl)-2-[(4-fluorophenyl)sulfanyl]acetamide
CAS 303091-24-9C18H20FNOS
2-[(4-Fluorophenyl)sulfanyl]-N-(3-nitrophenyl)acetamide chemical structure, C14H11FN2O3S, CAS 329778-07-6
2-[(4-Fluorophenyl)sulfanyl]-N-(3-nitrophenyl)acetamide
CAS 329778-07-6C14H11FN2O3S
2-(2,4-Dinitrophenylthio)-N-[3-(trifluoromethyl)phenyl]acetamide chemical structure, C15H10F3N3O5S, CAS 459181-94-3
2-(2,4-Dinitrophenylthio)-N-[3-(trifluoromethyl)phenyl]acetamide
CAS 459181-94-3C15H10F3N3O5S
N-(4-Acetamidophenyl)-2-[2-nitro-4-(trifluoromethylsulfonyl)phenyl]sulfanylacetamide chemical structure, C17H14F3N3O6S2, CAS 459188-30-8
N-(4-Acetamidophenyl)-2-[2-nitro-4-(trifluoromethylsulfonyl)phenyl]sulfanylacetamide
CAS 459188-30-8C17H14F3N3O6S2
2-[(4-Bromophenyl)sulfanyl]-N-(4-chloro-3-nitrophenyl)acetamide chemical structure, C14H10BrClN2O3S, CAS 329779-33-1
2-[(4-Bromophenyl)sulfanyl]-N-(4-chloro-3-nitrophenyl)acetamide
CAS 329779-33-1C14H10BrClN2O3S
N-[3,5-Bis(trifluoromethyl)phenyl]-2-[(4-chlorophenyl)sulfanyl]acetamide chemical structure, C16H10ClF6NOS, CAS 306732-33-2
N-[3,5-Bis(trifluoromethyl)phenyl]-2-[(4-chlorophenyl)sulfanyl]acetamide
CAS 306732-33-2C16H10ClF6NOS
N-[4-(Butan-2-yl)phenyl]-2-[(4-chlorophenyl)sulfanyl]acetamide chemical structure, C18H20ClNOS, CAS 329079-03-0
N-[4-(Butan-2-yl)phenyl]-2-[(4-chlorophenyl)sulfanyl]acetamide
CAS 329079-03-0C18H20ClNOS
2-{[N-(2,4,6-Trimethylphenyl)carbamoyl]methylthio}benzoic acid chemical structure, C18H19NO3S, CAS 540774-64-9
2-{[N-(2,4,6-Trimethylphenyl)carbamoyl]methylthio}benzoic acid
CAS 540774-64-9C18H19NO3S
2-((4-Methylphenyl)sulfanyl)-N-(2,3,4,5,6-pentafluorophenyl)acetamide chemical structure, C15H10F5NOS, CAS 301194-19-4
2-((4-Methylphenyl)sulfanyl)-N-(2,3,4,5,6-pentafluorophenyl)acetamide
CAS 301194-19-4C15H10F5NOS
N-(3-Chloro-4-methylphenyl)-2-[(4-chlorophenyl)sulfanyl]acetamide chemical structure, C15H13Cl2NOS, CAS 196712-32-0
N-(3-Chloro-4-methylphenyl)-2-[(4-chlorophenyl)sulfanyl]acetamide
CAS 196712-32-0C15H13Cl2NOS
2-((4-Aminophenyl)thio)-N-(4-butylphenyl)acetamide chemical structure, C18H22N2OS, CAS 763128-02-5
2-((4-Aminophenyl)thio)-N-(4-butylphenyl)acetamide
CAS 763128-02-5C18H22N2OS
2-[({[2-(Difluoromethoxy)phenyl]carbamoyl}methyl)sulfanyl]benzoic acid chemical structure, C16H13F2NO4S, CAS 790263-46-6
2-[({[2-(Difluoromethoxy)phenyl]carbamoyl}methyl)sulfanyl]benzoic acid
CAS 790263-46-6C16H13F2NO4S