Murcko scaffold
Ring system with 2 rings and 17 atoms
443 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 17
- Chemicals
- 443
- With full pages
- 77
Scaffold SMILES
O=C(CSc1ccccc1)Nc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 385 to 432 of 443 chemicals
N-(3,5-Dimethylphenyl)-2-((4-methoxyphenyl)thio)acetamide
CAS 941901-48-0C17H19NO2S
![2-({[(4-Chlorophenyl)sulfanyl]acetyl}amino)-N-[2-(dimethylamino)ethyl]benzamide chemical structure, C19H22ClN3O2S, CAS 947913-27-1](/s/CYPDIWZODQYQCU-UHFFFAOYSA-N.svg)
2-({[(4-Chlorophenyl)sulfanyl]acetyl}amino)-N-[2-(dimethylamino)ethyl]benzamide
CAS 947913-27-1C19H22ClN3O2S
![N-{4-[(Acetylamino)sulfonyl]phenyl}-2-[(4-aminophenyl)thio]propanamide chemical structure, C17H19N3O4S2, CAS 931293-01-5](/s/GDBKQIHJJJZWDK-UHFFFAOYSA-N.svg)
N-{4-[(Acetylamino)sulfonyl]phenyl}-2-[(4-aminophenyl)thio]propanamide
CAS 931293-01-5C17H19N3O4S2
![2-[(4-Aminophenyl)thio]-N-(3-methylphenyl)-propanamide chemical structure, C16H18N2OS, CAS 899016-19-4](/s/IOBOZATWQHICHW-UHFFFAOYSA-N.svg)
2-[(4-Aminophenyl)thio]-N-(3-methylphenyl)-propanamide
CAS 899016-19-4C16H18N2OS
![2-[(4-Aminophenyl)thio]-N-(4-methylphenyl)-propanamide chemical structure, C16H18N2OS, CAS 899016-25-2](/s/SYAJYLNZFCDTDF-UHFFFAOYSA-N.svg)
2-[(4-Aminophenyl)thio]-N-(4-methylphenyl)-propanamide
CAS 899016-25-2C16H18N2OS
![2-[(4-Aminophenyl)thio]-N-(2,4-dimethylphenyl)-propanamide chemical structure, C17H20N2OS, CAS 899588-82-0](/s/UHFAAPNMVLDBQC-UHFFFAOYSA-N.svg)
2-[(4-Aminophenyl)thio]-N-(2,4-dimethylphenyl)-propanamide
CAS 899588-82-0C17H20N2OS
![2-[(4-Aminophenyl)thio]-N-(2,5-dimethylphenyl)-propanamide chemical structure, C17H20N2OS, CAS 899588-89-7](/s/JSCMKUJKOLIUDT-UHFFFAOYSA-N.svg)
2-[(4-Aminophenyl)thio]-N-(2,5-dimethylphenyl)-propanamide
CAS 899588-89-7C17H20N2OS
![2-({[(4-Aminophenyl)thio]acetyl}amino)benzamide chemical structure, C15H15N3O2S, CAS 884798-64-5](/s/INBCHMQZPWITQW-UHFFFAOYSA-N.svg)
2-({[(4-Aminophenyl)thio]acetyl}amino)benzamide
CAS 884798-64-5C15H15N3O2S
![2-[(4-Aminophenyl)thio]-N-(3-chlorophenyl)-propanamide chemical structure, C15H15ClN2OS, CAS 899587-18-9](/s/NKTMGWPQYATAOO-UHFFFAOYSA-N.svg)
2-[(4-Aminophenyl)thio]-N-(3-chlorophenyl)-propanamide
CAS 899587-18-9C15H15ClN2OS
![N-(4-Acetylphenyl)-2-[(4-aminophenyl)thio]-propanamide chemical structure, C17H18N2O2S, CAS 899583-57-4](/s/FQGGCNOLUHUXBQ-UHFFFAOYSA-N.svg)
N-(4-Acetylphenyl)-2-[(4-aminophenyl)thio]-propanamide
CAS 899583-57-4C17H18N2O2S
![2-[(4-Aminophenyl)thio]-N-(2-ethyl-6-methylphenyl)propanamide chemical structure, C18H22N2OS, CAS 899584-11-3](/s/JVASNCDHVHAJNY-UHFFFAOYSA-N.svg)
2-[(4-Aminophenyl)thio]-N-(2-ethyl-6-methylphenyl)propanamide
CAS 899584-11-3C18H22N2OS
![2-[(4-Aminophenyl)thio]-N-(4-methoxyphenyl)-butanamide chemical structure, C17H20N2O2S, CAS 899588-98-8](/s/BXOINFDCEKBSEQ-UHFFFAOYSA-N.svg)
2-[(4-Aminophenyl)thio]-N-(4-methoxyphenyl)-butanamide
CAS 899588-98-8C17H20N2O2S
![2-[(4-Aminophenyl)thio]-N-(2-methyl-5-nitrophenyl)acetamide chemical structure, C15H15N3O3S, CAS 899589-24-3](/s/BEFYJLSBXADBAF-UHFFFAOYSA-N.svg)
2-[(4-Aminophenyl)thio]-N-(2-methyl-5-nitrophenyl)acetamide
CAS 899589-24-3C15H15N3O3S
![2-[(4-Aminophenyl)thio]-N-(4-nitrophenyl)-propanamide chemical structure, C15H15N3O3S, CAS 899589-31-2](/s/UJFBSKBKPSREJY-UHFFFAOYSA-N.svg)
2-[(4-Aminophenyl)thio]-N-(4-nitrophenyl)-propanamide
CAS 899589-31-2C15H15N3O3S
![N-[4-(Acetylamino)phenyl]-2-[(4-aminophenyl)thio]-propanamide chemical structure, C17H19N3O2S, CAS 913250-52-9](/s/BZKIMVUQTGWOLZ-UHFFFAOYSA-N.svg)
N-[4-(Acetylamino)phenyl]-2-[(4-aminophenyl)thio]-propanamide
CAS 913250-52-9C17H19N3O2S
![2-[(4-Aminophenyl)thio]-N-(3-chloro-4-methoxyphenyl)propanamide chemical structure, C16H17ClN2O2S, CAS 913251-32-8](/s/FSQDRWFOJNBSTP-UHFFFAOYSA-N.svg)
2-[(4-Aminophenyl)thio]-N-(3-chloro-4-methoxyphenyl)propanamide
CAS 913251-32-8C16H17ClN2O2S
![2-[(4-Aminophenyl)thio]-N-(4-chloro-2-methoxy-5-methylphenyl)acetamide chemical structure, C16H17ClN2O2S, CAS 913241-20-0](/s/NWRFVLFNTFGWJF-UHFFFAOYSA-N.svg)
2-[(4-Aminophenyl)thio]-N-(4-chloro-2-methoxy-5-methylphenyl)acetamide
CAS 913241-20-0C16H17ClN2O2S
![2-[(4-Aminophenyl)thio]-N-(5-chloro-2-methoxyphenyl)propanamide chemical structure, C16H17ClN2O2S, CAS 913241-23-3](/s/DJEIIMSIJWXHTD-UHFFFAOYSA-N.svg)
2-[(4-Aminophenyl)thio]-N-(5-chloro-2-methoxyphenyl)propanamide
CAS 913241-23-3C16H17ClN2O2S
![2-[(4-Aminophenyl)thio]-N-[3-(trifluoromethyl)-phenyl]propanamide chemical structure, C16H15F3N2OS, CAS 913242-28-1](/s/UWAAAUZTMKPFFH-UHFFFAOYSA-N.svg)
2-[(4-Aminophenyl)thio]-N-[3-(trifluoromethyl)-phenyl]propanamide
CAS 913242-28-1C16H15F3N2OS
![2-[(4-Aminophenyl)thio]-N-(2,5-dichlorophenyl)-propanamide chemical structure, C15H14Cl2N2OS, CAS 913250-51-8](/s/UFQQJJYAJZRBLS-UHFFFAOYSA-N.svg)
2-[(4-Aminophenyl)thio]-N-(2,5-dichlorophenyl)-propanamide
CAS 913250-51-8C15H14Cl2N2OS
![2-[(4-Aminophenyl)thio]-N-(3,5-dichlorophenyl)-propanamide chemical structure, C15H14Cl2N2OS, CAS 913250-56-3](/s/JSROSNJVDYDFER-UHFFFAOYSA-N.svg)
2-[(4-Aminophenyl)thio]-N-(3,5-dichlorophenyl)-propanamide
CAS 913250-56-3C15H14Cl2N2OS
![2-[(4-Aminophenyl)thio]-N-(2,3,5,6-tetrafluorophenyl)propanamide chemical structure, C15H12F4N2OS, CAS 913244-32-3](/s/FPNHKHPLCFNOOU-UHFFFAOYSA-N.svg)
2-[(4-Aminophenyl)thio]-N-(2,3,5,6-tetrafluorophenyl)propanamide
CAS 913244-32-3C15H12F4N2OS
![2-[(4-Aminophenyl)thio]-N-(2-bromophenyl)-propanamide chemical structure, C15H15BrN2OS, CAS 913246-00-1](/s/KXWQPEKGHMBRQJ-UHFFFAOYSA-N.svg)
2-[(4-Aminophenyl)thio]-N-(2-bromophenyl)-propanamide
CAS 913246-00-1C15H15BrN2OS
![2-[(4-Aminophenyl)thio]-N-[4-(aminosulfonyl)-phenyl]propanamide chemical structure, C15H17N3O3S2, CAS 913241-96-0](/s/ODJJOKMPVQJHIU-UHFFFAOYSA-N.svg)
2-[(4-Aminophenyl)thio]-N-[4-(aminosulfonyl)-phenyl]propanamide
CAS 913241-96-0C15H17N3O3S2
- Butyl 4-({[(4-aminophenyl)thio]acetyl}amino)-benzoate913247-25-3C19H22N2O3S
- 3-[[2-Oxo-2-(phenylamino)ethyl]thio]benzoic acid325703-99-9C15H13NO3S
- N-(4-Hydroxyphenyl)-2-((4-hydroxyphenyl)thio)acetamide443965-79-5C14H13NO3S
- N-(3-Hydroxyphenyl)-2-[(4-hydroxyphenyl)sulfanyl]acetamide471278-71-4C14H13NO3S
- 2-[(4-Methylphenyl)sulfanyl]-N-{4-[(propan-2-yl)sulfamoyl]phenyl}propanamide1008583-88-7C19H24N2O3S2
- N-(2-Cyanophenyl)-2-[(2,5-difluorophenyl)thio]acetamide1154008-67-9C15H10F2N2OS
- N-(2-Amino-4-chlorophenyl)-2-(phenylsulfanyl)acetamide1019367-36-2C14H13ClN2OS
- 2-[(4-tert-Butylphenyl)sulfanyl]-N-(cyanomethyl)-N-phenylacetamide1038152-02-1C20H22N2OS
- 2-[[2-[(3-Chloro-2-methylphenyl)amino]-2-oxoethyl]thio]benzoic acid440347-31-9C16H14ClNO3S
- N-Methyl-N-(4-nitrophenyl)-2-(phenylsulfanyl)acetamide75990-88-4C15H14N2O3S
- N-(Cyanomethyl)-2-[(2,6-dichlorophenyl)sulfanyl]-N-phenylacetamide1208683-47-9C16H12Cl2N2OS
- 2-[(4-Bromophenyl)thio]-N-(2-cyanophenyl)propanamide1097167-78-6C16H13BrN2OS
- 2-{2-[(2-Aminophenyl)sulfanyl]acetamido}benzamide902349-01-3C15H15N3O2S
- 2-[(2-Amino-4-methylphenyl)sulfanyl]-N-(2-methylphenyl)acetamide1095624-26-2C16H18N2OS
- 2-[(2-Amino-4-fluorophenyl)thio]-N-(2,6-difluorophenyl)acetamide1095559-58-2C14H11F3N2OS
- 2-[(2-Amino-4-fluorophenyl)thio]-N-(2,4-difluorophenyl)acetamide1095559-61-7C14H11F3N2OS
- N-(4-Aminophenyl)-2-[(2-bromophenyl)thio]propanamide1097829-73-6C15H15BrN2OS
- N-(3-Aminophenyl)-2-[(2,4-difluorophenyl)thio]acetamide1097824-60-6C14H12F2N2OS
- 2-(4-(2-((4-Fluorophenyl)thio)acetamido)phenyl)-N,N-dimethylacetamide1206989-57-2C18H19FN2O2S
- 2-{[4-Chloro-3-(trifluoromethyl)phenyl]sulfanyl}-N-(cyanomethyl)-N-phenylacetamide1209875-82-0C17H12ClF3N2OS
- 2-[(4-Bromophenyl)sulfanyl]-N-(cyanomethyl)-N-phenylacetamide1180099-80-2C16H13BrN2OS
- N-(Cyanomethyl)-N-phenyl-2-(phenylsulfanyl)propanamide1241594-72-8C17H16N2OS
- 2-((4-Fluorophenyl)thio)-N-(4-(2-((1-hydroxy-2-methylpropan-2-yl)amino)-2-oxoethyl)phenyl)acetamide1234994-67-2C20H23FN2O3S
- 2-((4-Fluorophenyl)thio)-N-(4-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)phenyl)acetamide1234805-34-5C18H16F4N2O2S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(COc1ccccc1)Nc1ccccc1476 chemicals
O=C(NN=Cc1ccccc1)c1ccccc1265 chemicals
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O=C(CCc1ccccc1)Nc1ccccc1153 chemicals
O=C(NCCc1ccccc1)c1ccccc1147 chemicals
S=C(NCc1ccccc1)Nc1ccccc1127 chemicals
O=C(CCNc1ccccc1)c1ccccc1120 chemicals
O=C(NC(=S)Nc1ccccc1)c1ccccc196 chemicals
O=S(=O)(NCCc1ccccc1)c1ccccc183 chemicals
O=C(CNc1ccccc1)Nc1ccccc183 chemicals
c1ccc(CCNCc2ccccc2)cc173 chemicals
O=C(NCc1ccccc1)Nc1ccccc171 chemicals