Murcko scaffold
1-(Thiophen-2-ylsulfonyl)piperidine scaffold
138 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 138
- With full pages
- 29
Scaffold SMILES
O=S(=O)(c1cccs1)N1CCCCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 138 chemicals
1-((5-Bromo-2-thienyl)sulfonyl)piperidine
CAS 81597-71-9C9H12BrNO2S2
4-Methyl-1-(2-thienylsulfonyl)piperidine
CAS 302552-66-5C10H15NO2S2
Ethyl1-(2-thienylsulfonyl)-4-piperidinecarboxylate
CAS 328032-17-3C12H17NO4S2
1-(Thiophen-2-ylsulfonyl)piperidine
CAS 53442-04-9C9H13NO2S2
1-(5-Chloro-thiophene-2-sulfonyl)-piperidine-4-carboxylic acid ethyl ester
CAS 440660-56-0C12H16ClNO4S2
![1-[(5-Bromo-2-thienyl)sulfonyl]-4-methylpiperidine chemical structure, C10H14BrNO2S2, CAS 641605-72-3](/s/CHEPIYWIJYHOPN-UHFFFAOYSA-N.svg)
1-[(5-Bromo-2-thienyl)sulfonyl]-4-methylpiperidine
CAS 641605-72-3C10H14BrNO2S2
![1-[(5-Bromo-2-thienyl)sulfonyl]-4-piperidinecarboxamide chemical structure, C10H13BrN2O3S2, CAS 578751-15-2](/s/ZCWMDXGYHHLODC-UHFFFAOYSA-N.svg)
1-[(5-Bromo-2-thienyl)sulfonyl]-4-piperidinecarboxamide
CAS 578751-15-2C10H13BrN2O3S2
![Ethyl 1-[(5-bromo-2-thienyl)sulfonyl]-4-piperidinecarboxylate chemical structure, C12H16BrNO4S2, CAS 577964-55-7](/s/AGJITPBMBVQALQ-UHFFFAOYSA-N.svg)
Ethyl 1-[(5-bromo-2-thienyl)sulfonyl]-4-piperidinecarboxylate
CAS 577964-55-7C12H16BrNO4S2
![1-[(5-Bromothien-2-yl)sulfonyl]piperidine-4-carboxylic acid chemical structure, C10H12BrNO4S2, CAS 496778-02-0](/s/YALGRHPGPRVWRS-UHFFFAOYSA-N.svg)
1-[(5-Bromothien-2-yl)sulfonyl]piperidine-4-carboxylic acid
CAS 496778-02-0C10H12BrNO4S2
![Dimethyl 3-methyl-5-[(4-methylpiperidin-1-yl)sulfonyl]thiophene-2,4-dicarboxylate chemical structure, C15H21NO6S2, CAS 612043-95-5](/s/DNYSXUKEPGUKBN-UHFFFAOYSA-N.svg)
Dimethyl 3-methyl-5-[(4-methylpiperidin-1-yl)sulfonyl]thiophene-2,4-dicarboxylate
CAS 612043-95-5C15H21NO6S2
1-Thiophen-2-ylsulfonylpiperidine-4-carboxamide
CAS 726164-46-1C10H14N2O3S2
2-Chloro-5-(piperidylsulfonyl)thiophene
CAS 385407-75-0C9H12ClNO2S2
1-((5-Chlorothiophen-2-yl)sulfonyl)piperidine-4-carboxylic acid
CAS 384847-76-1C10H12ClNO4S2
![1-{[3,5-Bis(methoxycarbonyl)-4-methylthiophen-2-yl]sulfonyl}piperidine-4-carboxylic acid chemical structure, C15H19NO8S2, CAS 731003-70-6](/s/ZIGOKIBQBDODBD-UHFFFAOYSA-N.svg)
1-{[3,5-Bis(methoxycarbonyl)-4-methylthiophen-2-yl]sulfonyl}piperidine-4-carboxylic acid
CAS 731003-70-6C15H19NO8S2
1-(Thiophene-2-sulfonyl)-piperidine-4-carboxylic acid
CAS 327971-19-7C10H13NO4S2
1-(Thiophene-2-sulfonyl)-piperidine-3-carboxylic acid
CAS 329909-94-6C10H13NO4S2
![1-[(5-Chloro-2-thienyl)sulfonyl]piperidine-3-carboxylic acid chemical structure, C10H12ClNO4S2, CAS 384847-77-2](/s/YUBGCBIDDMVVOC-UHFFFAOYSA-N.svg)
1-[(5-Chloro-2-thienyl)sulfonyl]piperidine-3-carboxylic acid
CAS 384847-77-2C10H12ClNO4S2
![1-[(5-Chloro-2-thienyl)sulfonyl]piperidine-2-carboxylic acid chemical structure, C10H12ClNO4S2, CAS 1008038-62-7](/s/DHYQCHGTXGSQDV-UHFFFAOYSA-N.svg)
1-[(5-Chloro-2-thienyl)sulfonyl]piperidine-2-carboxylic acid
CAS 1008038-62-7C10H12ClNO4S2
1-(Thiophen-2-ylsulfonyl)-3-(trifluoromethyl)piperidine
CAS 325702-34-9C10H12F3NO2S2
1-(5-Chloro-thiophene-2-sulfonyl)-3-methyl-piperidine
CAS 500149-12-2C10H14ClNO2S2
Ethyl 1-(thiophen-2-ylsulfonyl)piperidine-3-carboxylate
CAS 610259-52-4C12H17NO4S2
![1-[(5-Methylthiophen-2-yl)sulfonyl]piperidine-3-carboxylic acid chemical structure, C11H15NO4S2, CAS 610261-43-3](/s/QKLAHLXSXCSXCN-UHFFFAOYSA-N.svg)
1-[(5-Methylthiophen-2-yl)sulfonyl]piperidine-3-carboxylic acid
CAS 610261-43-3C11H15NO4S2
![Ethyl1-[(5-methyl-2-thienyl)sulfonyl]-4-piperidinecarboxylate chemical structure, C13H19NO4S2, CAS 620104-15-6](/s/WSMRSFCDYGNYAG-UHFFFAOYSA-N.svg)
Ethyl1-[(5-methyl-2-thienyl)sulfonyl]-4-piperidinecarboxylate
CAS 620104-15-6C13H19NO4S2
![1-[(5-Methyl-2-thienyl)sulfonyl]-2-piperidinecarboxylic acid chemical structure, C11H15NO4S2, CAS 1008703-84-1](/s/OACZNBYRQPECEM-UHFFFAOYSA-N.svg)
1-[(5-Methyl-2-thienyl)sulfonyl]-2-piperidinecarboxylic acid
CAS 1008703-84-1C11H15NO4S2
- 1 suppliers1-[(5-Bromo-2-thiophenyl)sulfonyl]-3-methylpiperidine723252-40-2C10H14BrNO2S2
- 1-[(5-Bromothiophen-2-yl)sulfonyl]piperidine-2-carboxylic acid1008571-93-4C10H12BrNO4S2
- Ethyl 1-[(5-methyl-2-thienyl)sulfonyl]piperidine-3-carboxylate620104-16-7C13H19NO4S2
- 1-(Thiophen-2-ylsulfonyl)piperidin-3-ol1153146-37-2C9H13NO3S2
- (1-(Thiophen-2-ylsulfonyl)piperidin-2-yl)methanol1022764-50-6C10H15NO3S2
- 2-Methyl-1-(2-thienylsulfonyl)piperidine897450-04-3C10H15NO2S2
- 1-((5-Bromothiophen-2-yl)sulfonyl)piperidin-3-ol1022383-19-2C9H12BrNO3S2
- (1-(Thiophen-2-ylsulfonyl)piperidin-3-yl)methanol1022210-55-4C10H15NO3S2
- 1-(Thiophen-2-ylsulfonyl)piperidine-3-carbohydrazide488118-79-2C10H15N3O3S2
- 2-[5-(Piperidine-1-sulfonyl)thiophen-2-yl]acetic acid379254-74-7C11H15NO4S2
- 1-[(5-Chlorothiophen-2-yl)sulfonyl]-3-(trifluoromethyl)piperidine500149-14-4C10H11ClF3NO2S2
- 1-((5-Bromo-2-thienyl)sulfonyl)-3-piperidinecarboxylic acid496778-03-1C10H12BrNO4S2
- 5-Chloro-2-[(4-methylpiperidyl)sulfonyl]thiophene500149-13-3C10H14ClNO2S2
- 5-Bromo-2-{[3-(trifluoromethyl)piperidyl]sulfonyl}thiophene496778-12-2C10H11BrF3NO2S2
- 1-((5-Bromothiophen-2-yl)sulfonyl)-2-methylpiperidine897449-94-4C10H14BrNO2S2
- 1-(Thiophen-2-ylsulfonyl)piperidin-4-ol913479-58-0C9H13NO3S2
- Methyl 1-(5-bromothiophen-2-yl)sulfonylpiperidine-4-carboxylate876904-16-4C11H14BrNO4S2
- 1-(Thiophene-2-sulfonyl)piperidine-2-carboxylic acid223562-16-1C10H13NO4S2
- [5-(Piperidine-1-sulfonyl)thiophen-2-yl]methanamine900137-40-8C10H16N2O2S2
- (5-(Piperidine-1-sulfonyl)thiophen-2-yl)methanamine hydrochloride1049741-22-1C10H17ClN2O2S2
- N-Methyl-1-(thiophene-2-sulfonyl)piperidine-3-carboxamide955171-87-6C11H16N2O3S2
- N1-propyl-N2-(2-(1-(thiophen-2-ylsulfonyl)piperidin-2-yl)ethyl)oxalamide898446-53-2C16H25N3O4S2
- N1-allyl-N2-(2-(1-(thiophen-2-ylsulfonyl)piperidin-2-yl)ethyl)oxalamide898415-84-4C16H23N3O4S2
- N1-(2-hydroxyethyl)-N2-(2-(1-(thiophen-2-ylsulfonyl)piperidin-2-yl)ethyl)oxalamide898415-87-7C15H23N3O5S2
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(Cn2cccn2)cc1271 chemicals
c1ccc(CN2CCCC2)cc1172 chemicals
O=S(=O)(c1ccccc1)N1CCCC1146 chemicals
c1ccc(Cn2ccnc2)cc1107 chemicals![Scaffold c1ccc(N=c2[nH]ccs2)cc1](/scaffold/OGVGQYZRJXSMGC-UHFFFAOYSA-N/structure.svg)
c1ccc(N=c2[nH]ccs2)cc198 chemicals
O=C1NC(=S)SC1=Cc1ccccc186 chemicals
O=C(c1ccccc1)N1CCCC186 chemicals
O=S(=O)(c1ccccc1)n1ccnc184 chemicals![Scaffold O=C(c1ccccc1)c1cc[nH]c1](/scaffold/DSNSKSWTLGZGAN-UHFFFAOYSA-N/structure.svg)
O=C(c1ccccc1)c1cc[nH]c177 chemicals
c1ccc(Cn2ccnn2)cc177 chemicals
c1ccc(Cc2cncs2)cc175 chemicals
c1ccc(Cn2cccc2)cc163 chemicals