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Murcko scaffold

Ring system with 3 rings and 20 atoms

24 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
24
With full pages
9
Scaffold SMILES

O=C(C=Cc1ccc(-c2ccccc2)o1)c1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccc(-c2ccccc2)o1)c1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

(2E)-1-(Furan-2-yl)-3-[5-(4-nitrophenyl)furan-2-yl]prop-2-en-1-one chemical structure, C17H11NO5, CAS 5618-60-0
(2E)-1-(Furan-2-yl)-3-[5-(4-nitrophenyl)furan-2-yl]prop-2-en-1-one
CAS 5618-60-0C17H11NO5
(2E)-1-(Furan-2-yl)-3-[5-(2-nitrophenyl)furan-2-yl]prop-2-en-1-one chemical structure, C17H11NO5, CAS 1262430-91-0
(2E)-1-(Furan-2-yl)-3-[5-(2-nitrophenyl)furan-2-yl]prop-2-en-1-one
CAS 1262430-91-0C17H11NO5
3-(5-(2-Chlorophenyl)-2-furyl)-1-(2-furyl)-2-propen-1-one chemical structure, C17H11ClO3, CAS 304896-61-5
3-(5-(2-Chlorophenyl)-2-furyl)-1-(2-furyl)-2-propen-1-one
CAS 304896-61-5C17H11ClO3
3-(5-(3-Chlorophenyl)-2-furyl)-1-(2-furyl)-2-propen-1-one chemical structure, C17H11ClO3, CAS 304896-62-6
3-(5-(3-Chlorophenyl)-2-furyl)-1-(2-furyl)-2-propen-1-one
CAS 304896-62-6C17H11ClO3
(E)-3-(5-(3,4-Dichlorophenyl)furan-2-yl)-1-(furan-2-yl)prop-2-en-1-one chemical structure, C17H10Cl2O3, CAS 307504-73-0
(E)-3-(5-(3,4-Dichlorophenyl)furan-2-yl)-1-(furan-2-yl)prop-2-en-1-one
CAS 307504-73-0C17H10Cl2O3
(2E)-3-[5-(4-Chlorophenyl)furan-2-yl]-1-(furan-2-yl)prop-2-en-1-one chemical structure, C17H11ClO3, CAS 1492902-61-0
(2E)-3-[5-(4-Chlorophenyl)furan-2-yl]-1-(furan-2-yl)prop-2-en-1-one
CAS 1492902-61-0C17H11ClO3
(E)-1-(Furan-2-yl)-3-(5-phenylfuran-2-yl)prop-2-en-1-one chemical structure, C17H12O3, CAS 40940-98-5
(E)-1-(Furan-2-yl)-3-(5-phenylfuran-2-yl)prop-2-en-1-one
CAS 40940-98-5C17H12O3
(E)-3-[5-(2,5-Dichlorophenyl)furan-2-yl]-1-(furan-2-yl)prop-2-en-1-one chemical structure, C17H10Cl2O3, CAS 304896-63-7
(E)-3-[5-(2,5-Dichlorophenyl)furan-2-yl]-1-(furan-2-yl)prop-2-en-1-one
CAS 304896-63-7C17H10Cl2O3
(E)-1-(Furan-2-yl)-3-(5-(3-(trifluoromethyl)phenyl)furan-2-yl)prop-2-en-1-one chemical structure, C18H11F3O3, CAS 5860-32-2
(E)-1-(Furan-2-yl)-3-(5-(3-(trifluoromethyl)phenyl)furan-2-yl)prop-2-en-1-one
CAS 5860-32-2C18H11F3O3
(E)-3-(5-(3-Bromophenyl)furan-2-yl)-1-(furan-2-yl)prop-2-en-1-one chemical structure, C17H11BrO3, CAS 6015-47-0
(E)-3-(5-(3-Bromophenyl)furan-2-yl)-1-(furan-2-yl)prop-2-en-1-one
CAS 6015-47-0C17H11BrO3
(2E)-3-[5-(2,4-Dichlorophenyl)furan-2-yl]-1-(furan-2-yl)prop-2-en-1-one chemical structure, C17H10Cl2O3, CAS 6116-53-6
(2E)-3-[5-(2,4-Dichlorophenyl)furan-2-yl]-1-(furan-2-yl)prop-2-en-1-one
CAS 6116-53-6C17H10Cl2O3
(E)-1-(Furan-2-yl)-3-[5-(3-nitrophenyl)furan-2-yl]prop-2-en-1-one chemical structure, C17H11NO5, CAS 1262430-92-1
(E)-1-(Furan-2-yl)-3-[5-(3-nitrophenyl)furan-2-yl]prop-2-en-1-one
CAS 1262430-92-1C17H11NO5
(2E)-3-[5-(4-Bromophenyl)furan-2-yl]-1-(furan-2-yl)prop-2-en-1-one chemical structure, C17H11BrO3, CAS 20005-36-1
(2E)-3-[5-(4-Bromophenyl)furan-2-yl]-1-(furan-2-yl)prop-2-en-1-one
CAS 20005-36-1C17H11BrO3
(2E)-1-(Furan-2-yl)-3-[5-(4-methylphenyl)furan-2-yl]prop-2-en-1-one chemical structure, C18H14O3, CAS 40940-99-6
(2E)-1-(Furan-2-yl)-3-[5-(4-methylphenyl)furan-2-yl]prop-2-en-1-one
CAS 40940-99-6C18H14O3
(2E)-1-(Furan-2-yl)-3-[5-(2-methoxyphenyl)furan-2-yl]prop-2-en-1-one chemical structure, C18H14O4, CAS 1351404-42-6
(2E)-1-(Furan-2-yl)-3-[5-(2-methoxyphenyl)furan-2-yl]prop-2-en-1-one
CAS 1351404-42-6C18H14O4
(E)-1-(5-Methylfuran-2-yl)-3-[5-(4-methylphenyl)furan-2-yl]prop-2-en-1-one chemical structure, C19H16O3, CAS 1351507-51-1
(E)-1-(5-Methylfuran-2-yl)-3-[5-(4-methylphenyl)furan-2-yl]prop-2-en-1-one
CAS 1351507-51-1C19H16O3
(2E)-1-(5-Methylfuran-2-yl)-3-[5-(3-nitrophenyl)furan-2-yl]prop-2-en-1-one chemical structure, C18H13NO5, CAS 373618-80-5
(2E)-1-(5-Methylfuran-2-yl)-3-[5-(3-nitrophenyl)furan-2-yl]prop-2-en-1-one
CAS 373618-80-5C18H13NO5
(E)-1-(Furan-2-yl)-3-(5-(4-methoxyphenyl)furan-2-yl)prop-2-en-1-one chemical structure, C18H14O4, CAS 40941-00-2
(E)-1-(Furan-2-yl)-3-(5-(4-methoxyphenyl)furan-2-yl)prop-2-en-1-one
CAS 40941-00-2C18H14O4
(E)-3-[5-[2-Chloro-5-(trifluoromethyl)phenyl]furan-2-yl]-1-(furan-2-yl)prop-2-en-1-one chemical structure, C18H10ClF3O3, CAS 432510-21-9
(E)-3-[5-[2-Chloro-5-(trifluoromethyl)phenyl]furan-2-yl]-1-(furan-2-yl)prop-2-en-1-one
CAS 432510-21-9C18H10ClF3O3
(E)-3-[5-(2-Chloro-4-nitrophenyl)furan-2-yl]-1-(furan-2-yl)prop-2-en-1-one chemical structure, C17H10ClNO5, CAS 432532-17-7
(E)-3-[5-(2-Chloro-4-nitrophenyl)furan-2-yl]-1-(furan-2-yl)prop-2-en-1-one
CAS 432532-17-7C17H10ClNO5
(2E)-3-(5-{4-[(Difluoromethyl)sulfanyl]phenyl}furan-2-yl)-1-(furan-2-yl)prop-2-en-1-one chemical structure, C18H12F2O3S, CAS 461682-58-6
(2E)-3-(5-{4-[(Difluoromethyl)sulfanyl]phenyl}furan-2-yl)-1-(furan-2-yl)prop-2-en-1-one
CAS 461682-58-6C18H12F2O3S
(E)-1-(Furan-2-yl)-3-[5-(4-methyl-2-nitrophenyl)furan-2-yl]prop-2-en-1-one chemical structure, C18H13NO5, CAS 501349-87-7
(E)-1-(Furan-2-yl)-3-[5-(4-methyl-2-nitrophenyl)furan-2-yl]prop-2-en-1-one
CAS 501349-87-7C18H13NO5
(E)-3-[5-(4-Fluorophenyl)furan-2-yl]-1-(furan-2-yl)prop-2-en-1-one chemical structure, C17H11FO3, CAS 301312-55-0
(E)-3-[5-(4-Fluorophenyl)furan-2-yl]-1-(furan-2-yl)prop-2-en-1-one
CAS 301312-55-0C17H11FO3
(E)-3-(5-(4-Fluorophenyl)furan-2-yl)-1-(5-methylfuran-2-yl)prop-2-en-1-one chemical structure, C18H13FO3, CAS 327078-33-1
(E)-3-(5-(4-Fluorophenyl)furan-2-yl)-1-(5-methylfuran-2-yl)prop-2-en-1-one
CAS 327078-33-1C18H13FO3