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Murcko scaffold

Ring system with 3 rings and 21 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
7
With full pages
4
Scaffold SMILES

O=C(NCC1CCCO1)C1CC(=O)N(c2ccccc2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCC1CCCO1)C1CC(=O)N(c2ccccc2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

1-(4-Bromophenyl)-5-oxo-N-(oxolan-2-ylmethyl)pyrrolidine-3-carboxamide chemical structure, C16H19BrN2O3, CAS 309921-66-2
1-(4-Bromophenyl)-5-oxo-N-(oxolan-2-ylmethyl)pyrrolidine-3-carboxamide
CAS 309921-66-2C16H19BrN2O3
1-(4-Methoxyphenyl)-5-oxo-N-(oxolan-2-ylmethyl)pyrrolidine-3-carboxamide chemical structure, C17H22N2O4, CAS 296893-44-2
1-(4-Methoxyphenyl)-5-oxo-N-(oxolan-2-ylmethyl)pyrrolidine-3-carboxamide
CAS 296893-44-2C17H22N2O4
1-(4-Ethoxyphenyl)-5-oxo-N-(oxolan-2-ylmethyl)pyrrolidine-3-carboxamide chemical structure, C18H24N2O4, CAS 440109-34-2
1-(4-Ethoxyphenyl)-5-oxo-N-(oxolan-2-ylmethyl)pyrrolidine-3-carboxamide
CAS 440109-34-2C18H24N2O4
1-(3-Chloro-4-methylphenyl)-5-oxo-N-(oxolan-2-ylmethyl)pyrrolidine-3-carboxamide chemical structure, C17H21ClN2O3, CAS 713081-14-2
1-(3-Chloro-4-methylphenyl)-5-oxo-N-(oxolan-2-ylmethyl)pyrrolidine-3-carboxamide
CAS 713081-14-2C17H21ClN2O3
1-(3-Chlorophenyl)-5-oxo-N-((tetrahydro-2-furanyl)methyl)-3-pyrrolidinecarboxamide chemical structure, C16H19ClN2O3, CAS 876715-26-3
1-(3-Chlorophenyl)-5-oxo-N-((tetrahydro-2-furanyl)methyl)-3-pyrrolidinecarboxamide
CAS 876715-26-3C16H19ClN2O3
1-(3,4-Dimethylphenyl)-5-oxo-N-(tetrahydrofuran-2-ylmethyl)pyrrolidine-3-carboxamide chemical structure, C18H24N2O3, CAS 897917-42-9
1-(3,4-Dimethylphenyl)-5-oxo-N-(tetrahydrofuran-2-ylmethyl)pyrrolidine-3-carboxamide
CAS 897917-42-9C18H24N2O3
1-(2,5-Dimethoxyphenyl)-5-oxo-N-(tetrahydrofuran-2-ylmethyl)pyrrolidine-3-carboxamide chemical structure, C18H24N2O5, CAS 925136-63-6
1-(2,5-Dimethoxyphenyl)-5-oxo-N-(tetrahydrofuran-2-ylmethyl)pyrrolidine-3-carboxamide
CAS 925136-63-6C18H24N2O5