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Murcko scaffold

Ring system with 3 rings and 20 atoms

20 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 20
Chemicals: 20
With full pages: 4

Scaffold SMILES

O=C(C=Cc1ccc(-c2ccccc2)o1)c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(C=Cc1ccc(-c2ccccc2)o1)c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

3-(5-(4-Nitrophenyl)-2-furyl)-1-(2-thienyl)-2-propen-1-one chemical structure, C17H11NO4S, CAS 304677-48-3

3-(5-(4-Nitrophenyl)-2-furyl)-1-(2-thienyl)-2-propen-1-one

CAS 304677-48-3C₁₇H₁₁NO₄S

(E)-3-(5-Phenylfuran-2-yl)-1-(thiophen-2-yl)prop-2-en-1-one chemical structure, C17H12O2S, CAS 301229-16-3

(E)-3-(5-Phenylfuran-2-yl)-1-(thiophen-2-yl)prop-2-en-1-one

CAS 301229-16-3C₁₇H₁₂O₂S

(E)-3-[5-(2,5-Dichlorophenyl)furan-2-yl]-1-thiophen-2-ylprop-2-en-1-one chemical structure, C17H10Cl2O2S, CAS 304896-66-0

(E)-3-[5-(2,5-Dichlorophenyl)furan-2-yl]-1-thiophen-2-ylprop-2-en-1-one

CAS 304896-66-0C₁₇H₁₀Cl₂O₂S

(E)-3-(5-(2-Chlorophenyl)furan-2-yl)-1-(thiophen-2-yl)prop-2-en-1-one chemical structure, C17H11ClO2S, CAS 304896-67-1

(E)-3-(5-(2-Chlorophenyl)furan-2-yl)-1-(thiophen-2-yl)prop-2-en-1-one

CAS 304896-67-1C₁₇H₁₁ClO₂S

(2E)-3-[5-(4-Chlorophenyl)furan-2-yl]-1-(thiophen-2-yl)prop-2-en-1-one chemical structure, C17H11ClO2S, CAS 307504-74-1

(2E)-3-[5-(4-Chlorophenyl)furan-2-yl]-1-(thiophen-2-yl)prop-2-en-1-one

CAS 307504-74-1C₁₇H₁₁ClO₂S

(E)-3-(5-(3-Nitrophenyl)furan-2-yl)-1-(thiophen-2-yl)prop-2-en-1-one chemical structure, C17H11NO4S, CAS 1262430-85-2

(E)-3-(5-(3-Nitrophenyl)furan-2-yl)-1-(thiophen-2-yl)prop-2-en-1-one

CAS 1262430-85-2C₁₇H₁₁NO₄S

(2E)-3-[5-(3-Chlorophenyl)furan-2-yl]-1-(thiophen-2-yl)prop-2-en-1-one chemical structure, C17H11ClO2S, CAS 304896-68-2

(2E)-3-[5-(3-Chlorophenyl)furan-2-yl]-1-(thiophen-2-yl)prop-2-en-1-one

CAS 304896-68-2C₁₇H₁₁ClO₂S

(E)-3-[5-(2,3-Dichlorophenyl)furan-2-yl]-1-thiophen-2-ylprop-2-en-1-one chemical structure, C17H10Cl2O2S, CAS 304896-65-9

(E)-3-[5-(2,3-Dichlorophenyl)furan-2-yl]-1-thiophen-2-ylprop-2-en-1-one

CAS 304896-65-9C₁₇H₁₀Cl₂O₂S

(E)-3-[5-(3-Bromophenyl)furan-2-yl]-1-thiophen-2-ylprop-2-en-1-one chemical structure, C17H11BrO2S, CAS 315240-89-2

(E)-3-[5-(3-Bromophenyl)furan-2-yl]-1-thiophen-2-ylprop-2-en-1-one

CAS 315240-89-2C₁₇H₁₁BrO₂S

3-(5-(2-Nitrophenyl)-2-furyl)-1-(2-thienyl)-2-propen-1-one chemical structure, C17H11NO4S, CAS 304677-46-1

3-(5-(2-Nitrophenyl)-2-furyl)-1-(2-thienyl)-2-propen-1-one

CAS 304677-46-1C₁₇H₁₁NO₄S

(E)-1-(Thiophen-2-yl)-3-(5-(3-(trifluoromethyl)phenyl)furan-2-yl)prop-2-en-1-one chemical structure, C18H11F3O2S, CAS 304896-70-6

(E)-1-(Thiophen-2-yl)-3-(5-(3-(trifluoromethyl)phenyl)furan-2-yl)prop-2-en-1-one

CAS 304896-70-6C₁₈H₁₁F₃O₂S

(E)-1-(Thiophen-2-yl)-3-(5-(p-tolyl)furan-2-yl)prop-2-en-1-one chemical structure, C18H14O2S, CAS 301312-56-1

(E)-1-(Thiophen-2-yl)-3-(5-(p-tolyl)furan-2-yl)prop-2-en-1-one

CAS 301312-56-1C₁₈H₁₄O₂S

(E)-3-(5-(4-Bromophenyl)furan-2-yl)-1-(thiophen-2-yl)prop-2-en-1-one chemical structure, C17H11BrO2S, CAS 307504-75-2

(E)-3-(5-(4-Bromophenyl)furan-2-yl)-1-(thiophen-2-yl)prop-2-en-1-one

CAS 307504-75-2C₁₇H₁₁BrO₂S

(E)-3-[5-(3,4-Dichlorophenyl)furan-2-yl]-1-thiophen-2-ylprop-2-en-1-one chemical structure, C17H10Cl2O2S, CAS 307504-76-3

(E)-3-[5-(3,4-Dichlorophenyl)furan-2-yl]-1-thiophen-2-ylprop-2-en-1-one

CAS 307504-76-3C₁₇H₁₀Cl₂O₂S

(E)-3-[5-(2,4-Dichlorophenyl)furan-2-yl]-1-thiophen-2-ylprop-2-en-1-one chemical structure, C17H10Cl2O2S, CAS 314259-15-9

(E)-3-[5-(2,4-Dichlorophenyl)furan-2-yl]-1-thiophen-2-ylprop-2-en-1-one

CAS 314259-15-9C₁₇H₁₀Cl₂O₂S

(E)-3-[5-[2-Chloro-5-(trifluoromethyl)phenyl]furan-2-yl]-1-thiophen-2-ylprop-2-en-1-one chemical structure, C18H10ClF3O2S, CAS 431996-38-2

(E)-3-[5-[2-Chloro-5-(trifluoromethyl)phenyl]furan-2-yl]-1-thiophen-2-ylprop-2-en-1-one

CAS 431996-38-2C₁₈H₁₀ClF₃O₂S

(E)-3-[5-(2-Chloro-4-nitrophenyl)furan-2-yl]-1-thiophen-2-ylprop-2-en-1-one chemical structure, C17H10ClNO4S, CAS 432537-02-5

(E)-3-[5-(2-Chloro-4-nitrophenyl)furan-2-yl]-1-thiophen-2-ylprop-2-en-1-one

CAS 432537-02-5C₁₇H₁₀ClNO₄S

(E)-3-(5-(4-Methyl-2-nitrophenyl)furan-2-yl)-1-(thiophen-2-yl)prop-2-en-1-one chemical structure, C18H13NO4S, CAS 627890-54-4

(E)-3-(5-(4-Methyl-2-nitrophenyl)furan-2-yl)-1-(thiophen-2-yl)prop-2-en-1-one

CAS 627890-54-4C₁₈H₁₃NO₄S

(E)-3-[5-(2,6-Dichlorophenyl)furan-2-yl]-1-thiophen-2-ylprop-2-en-1-one chemical structure, C17H10Cl2O2S, CAS 627072-29-1

(E)-3-[5-(2,6-Dichlorophenyl)furan-2-yl]-1-thiophen-2-ylprop-2-en-1-one

CAS 627072-29-1C₁₇H₁₀Cl₂O₂S

(E)-3-(5-(2-Bromophenyl)furan-2-yl)-1-(thiophen-2-yl)prop-2-en-1-one chemical structure, C17H11BrO2S, CAS 327078-21-7

(E)-3-(5-(2-Bromophenyl)furan-2-yl)-1-(thiophen-2-yl)prop-2-en-1-one

CAS 327078-21-7C₁₇H₁₁BrO₂S