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Murcko scaffold

Ring system with 3 rings and 16 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
14
With full pages
4
Scaffold SMILES

O=C(c1ccn[nH]1)N1CCc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccn[nH]1)N1CCc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

(4-Chloro-2-methylpyrazol-3-yl)-(2,3-dihydroindol-1-yl)methanone chemical structure, C13H12ClN3O, CAS 386749-26-4
(4-Chloro-2-methylpyrazol-3-yl)-(2,3-dihydroindol-1-yl)methanone
CAS 386749-26-4C13H12ClN3O
1-[(4-Bromo-1,5-dimethyl-1H-pyrazol-3-yl)carbonyl]indoline chemical structure, C14H14BrN3O, CAS 514815-97-5
1-[(4-Bromo-1,5-dimethyl-1H-pyrazol-3-yl)carbonyl]indoline
CAS 514815-97-5C14H14BrN3O
2,3-Dihydroindol-1-yl-[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]methanone chemical structure, C14H12F3N3O, CAS 515830-08-7
2,3-Dihydroindol-1-yl-[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]methanone
CAS 515830-08-7C14H12F3N3O
1-[(4-Bromo-1-methyl-1H-pyrazol-3-yl)carbonyl]indoline chemical structure, C13H12BrN3O, CAS 514217-47-1
1-[(4-Bromo-1-methyl-1H-pyrazol-3-yl)carbonyl]indoline
CAS 514217-47-1C13H12BrN3O
1-[(4-Bromo-1-methyl-1H-pyrazol-3-yl)carbonyl]-2-methylindoline chemical structure, C14H14BrN3O, CAS 515847-53-7
1-[(4-Bromo-1-methyl-1H-pyrazol-3-yl)carbonyl]-2-methylindoline
CAS 515847-53-7C14H14BrN3O
(4-Iodo-1-methylpyrazol-3-yl)-(2-methyl-2,3-dihydroindol-1-yl)methanone chemical structure, C14H14IN3O, CAS 490013-40-6
(4-Iodo-1-methylpyrazol-3-yl)-(2-methyl-2,3-dihydroindol-1-yl)methanone
CAS 490013-40-6C14H14IN3O
(4-Chloro-1,5-dimethylpyrazol-3-yl)-(2,3-dihydroindol-1-yl)methanone chemical structure, C14H14ClN3O, CAS 514800-19-2
(4-Chloro-1,5-dimethylpyrazol-3-yl)-(2,3-dihydroindol-1-yl)methanone
CAS 514800-19-2C14H14ClN3O
[4-Bromo-2-methyl-5-(trifluoromethyl)pyrazol-3-yl]-(2,3-dihydroindol-1-yl)methanone chemical structure, C14H11BrF3N3O, CAS 1005677-42-8
[4-Bromo-2-methyl-5-(trifluoromethyl)pyrazol-3-yl]-(2,3-dihydroindol-1-yl)methanone
CAS 1005677-42-8C14H11BrF3N3O
[4-Chloro-1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-(2,3-dihydroindol-1-yl)methanone chemical structure, C14H11ClF3N3O, CAS 1005558-08-6
[4-Chloro-1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-(2,3-dihydroindol-1-yl)methanone
CAS 1005558-08-6C14H11ClF3N3O
5-(2,3-Dihydro-1H-indol-1-ylcarbonyl)-N,N-diethyl-1-methyl-1H-pyrazole-3-carboxamide chemical structure, C18H22N4O2, CAS 1006328-36-4
5-(2,3-Dihydro-1H-indol-1-ylcarbonyl)-N,N-diethyl-1-methyl-1H-pyrazole-3-carboxamide
CAS 1006328-36-4C18H22N4O2
2-[3-(2,3-Dihydro-1H-indole-1-carbonyl)-1H-pyrazol-1-yl]propanoic acid chemical structure, C15H15N3O3, CAS 1006471-21-1
2-[3-(2,3-Dihydro-1H-indole-1-carbonyl)-1H-pyrazol-1-yl]propanoic acid
CAS 1006471-21-1C15H15N3O3
3-[(2,3-Dihydro-2-methyl-1H-indol-1-yl)carbonyl]-1H-pyrazole-1-propanoic acid chemical structure, C16H17N3O3, CAS 1006435-73-9
3-[(2,3-Dihydro-2-methyl-1H-indol-1-yl)carbonyl]-1H-pyrazole-1-propanoic acid
CAS 1006435-73-9C16H17N3O3
5-(2,3-Dihydro-1H-indol-1-ylcarbonyl)-1-methyl-1H-pyrazole-4-carboxylic acid chemical structure, C14H13N3O3, CAS 1006476-71-6
5-(2,3-Dihydro-1H-indol-1-ylcarbonyl)-1-methyl-1H-pyrazole-4-carboxylic acid
CAS 1006476-71-6C14H13N3O3
(5-Bromoindolin-1-yl)-(2-methylpyrazol-3-yl)methanone chemical structure, C13H12BrN3O, CAS 2279912-92-2
(5-Bromoindolin-1-yl)-(2-methylpyrazol-3-yl)methanone
CAS 2279912-92-2C13H12BrN3O