CompoundList
Sign in
Murcko scaffold

5-(1H-Indol-3-ylmethyl)imidazolidine-2,4-dione scaffold

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
16
With full pages
7
Scaffold SMILES

O=C1NC(=O)C(Cc2c[nH]c3ccccc23)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-(1H-Indol-3-ylmethyl)imidazolidine-2,4-dione page
Murcko scaffold O=C1NC(=O)C(Cc2c[nH]c3ccccc23)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

5-(1H-Indol-3-ylmethyl)-3-methyl-2,4-imidazolidinedione chemical structure, C13H13N3O2, CAS 74311-00-5
5-(1H-Indol-3-ylmethyl)-3-methyl-2,4-imidazolidinedione
CAS 74311-00-5C13H13N3O2
5-(1H-Indol-3-ylmethyl)imidazolidine-2,4-dione chemical structure, C12H11N3O2, CAS 21753-16-2
5-(1H-Indol-3-ylmethyl)imidazolidine-2,4-dione
CAS 21753-16-2C12H11N3O2
Necrostatin-1s chemical structure, C13H12ClN3O2, CAS 852391-15-2
Necrostatin-1s
CAS 852391-15-2C13H12ClN3O2
(5S)-5-[(1H-Indol-3-yl)methyl]imidazolidine-2,4-dione chemical structure, C12H11N3O2, CAS 40856-80-2
(5S)-5-[(1H-Indol-3-yl)methyl]imidazolidine-2,4-dione
CAS 40856-80-2C12H11N3O2
(5R)-5-[(1H-Indol-3-yl)methyl]imidazolidine-2,4-dione chemical structure, C12H11N3O2, CAS 62498-87-7
(5R)-5-[(1H-Indol-3-yl)methyl]imidazolidine-2,4-dione
CAS 62498-87-7C12H11N3O2
(5R)-5-[(7-Chloro-1H-indol-3-yl)methyl]-3-methylimidazolidine-2,4-dione chemical structure, C13H12ClN3O2, CAS 852391-19-6
(5R)-5-[(7-Chloro-1H-indol-3-yl)methyl]-3-methylimidazolidine-2,4-dione
CAS 852391-19-6C13H12ClN3O2
2,4-Imidazolidinedione, 5-[(5-hydroxy-1H-indol-3-yl)methyl]-, (S)- chemical structure, C12H11N3O3, CAS 109063-48-1
2,4-Imidazolidinedione, 5-[(5-hydroxy-1H-indol-3-yl)methyl]-, (S)-
CAS 109063-48-1C12H11N3O3
2-{4-[(1H-Indol-3-yl)methyl]-2,5-dioxoimidazolidin-1-yl}-N-(3-methylbutan-2-yl)acetamide chemical structure, C19H24N4O3, CAS 1206154-73-5
2-{4-[(1H-Indol-3-yl)methyl]-2,5-dioxoimidazolidin-1-yl}-N-(3-methylbutan-2-yl)acetamide
CAS 1206154-73-5C19H24N4O3
3-Methyl-5-[(7-methyl-1H-indol-3-yl)methyl]-2,4-imidazolidinedione chemical structure, C14H15N3O2, CAS 852391-16-3
3-Methyl-5-[(7-methyl-1H-indol-3-yl)methyl]-2,4-imidazolidinedione
CAS 852391-16-3C14H15N3O2
Necrostatin 2 S enantiomer chemical structure, C13H12ClN3O2, CAS 852391-20-9
Necrostatin 2 S enantiomer
CAS 852391-20-9C13H12ClN3O2
3-(2-Chloroethyl)-5-[(1H-indol-3-yl)methyl]imidazolidine-2,4-dione chemical structure, C14H14ClN3O2, CAS 90124-72-4
3-(2-Chloroethyl)-5-[(1H-indol-3-yl)methyl]imidazolidine-2,4-dione
CAS 90124-72-4C14H14ClN3O2
Necroptosis-IN-1 chemical structure, C12H10ClN3O2, CAS 1391980-92-9
Necroptosis-IN-1
CAS 1391980-92-9C12H10ClN3O2
5-((1H-Indol-3-yl)methyl)-3-allylimidazolidine-2,4-dione chemical structure, C15H15N3O2, CAS 160448-64-6
5-((1H-Indol-3-yl)methyl)-3-allylimidazolidine-2,4-dione
CAS 160448-64-6C15H15N3O2
5-((4-Methoxy-1H-indol-3-yl)methyl)imidazolidine-2,4-dione chemical structure, C13H13N3O3, CAS 2102408-76-2
5-((4-Methoxy-1H-indol-3-yl)methyl)imidazolidine-2,4-dione
CAS 2102408-76-2C13H13N3O3
5-[(5-Fluoro-1H-indol-3-yl)methyl]imidazolidine-2,4-dione chemical structure, C12H10FN3O2, CAS 2748165-90-2
5-[(5-Fluoro-1H-indol-3-yl)methyl]imidazolidine-2,4-dione
CAS 2748165-90-2C12H10FN3O2
5-((1H-Indol-3-yl)methyl)-3-isobutylimidazolidine-2,4-dione chemical structure, C16H19N3O2, CAS 2774441-10-8
5-((1H-Indol-3-yl)methyl)-3-isobutylimidazolidine-2,4-dione
CAS 2774441-10-8C16H19N3O2