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Murcko scaffold

Ring system with 3 rings and 16 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
11
With full pages
3
Scaffold SMILES

O=c1[nH]cc(C=C2C=Nc3ccccc32)s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]cc(C=C2C=Nc3ccccc32)s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

3-Thiazolidineacetic acid, 5-[(5-bromo-1H-indol-3-yl)methylene]-2,4-dioxo-, methyl ester chemical structure, C15H11BrN2O4S, CAS 593272-22-1
3-Thiazolidineacetic acid, 5-[(5-bromo-1H-indol-3-yl)methylene]-2,4-dioxo-, methyl ester
CAS 593272-22-1C15H11BrN2O4S
(5Z)-5-[(1H-Indol-3-yl)methylidene]-4-sulfanylidene-1,3-thiazolidin-2-one chemical structure, C12H8N2OS2
(5Z)-5-[(1H-Indol-3-yl)methylidene]-4-sulfanylidene-1,3-thiazolidin-2-one
C12H8N2OS2
3-Thiazolidineacetic acid, 5-(1H-indol-3-ylmethylene)-alpha-methyl-2,4-dioxo-, methyl ester chemical structure, C16H14N2O4S, CAS 593266-04-7
3-Thiazolidineacetic acid, 5-(1H-indol-3-ylmethylene)-alpha-methyl-2,4-dioxo-, methyl ester
CAS 593266-04-7C16H14N2O4S
5-[(E)-1H-Indol-3-ylmethylidene]-3-methyl-1,3-thiazolane-2,4-dione chemical structure, C13H10N2O2S, CAS 365989-89-5
5-[(E)-1H-Indol-3-ylmethylidene]-3-methyl-1,3-thiazolane-2,4-dione
CAS 365989-89-5C13H10N2O2S
Methyl 3-[(2,4-dioxo-1,3-thiazolan-5-yliden)methyl]-1H-indole-2-carboxylate chemical structure, C14H10N2O4S, CAS 860612-09-5
Methyl 3-[(2,4-dioxo-1,3-thiazolan-5-yliden)methyl]-1H-indole-2-carboxylate
CAS 860612-09-5C14H10N2O4S
(Z)-5-((1H-Indol-3-yl)methylene)thiazolidine-2,4-dione chemical structure, C12H8N2O2S, CAS 139336-32-6
(Z)-5-((1H-Indol-3-yl)methylene)thiazolidine-2,4-dione
CAS 139336-32-6C12H8N2O2S
(5E)-3-Ethyl-5-(1H-indol-3-ylmethylidene)-1,3-thiazolidine-2,4-dione chemical structure, C14H12N2O2S, CAS 676622-45-0
(5E)-3-Ethyl-5-(1H-indol-3-ylmethylidene)-1,3-thiazolidine-2,4-dione
CAS 676622-45-0C14H12N2O2S
(5Z)-5-(1H-Indol-3-ylmethylidene)-4-sulfanylidene-1,3-thiazolidin-2-one chemical structure, C12H8N2OS2, CAS 131841-95-7
(5Z)-5-(1H-Indol-3-ylmethylidene)-4-sulfanylidene-1,3-thiazolidin-2-one
CAS 131841-95-7C12H8N2OS2
Ethyl {(5E)-5-[(5-bromo-1H-indol-3-yl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl}acetate chemical structure, C16H13BrN2O4S, CAS 432017-16-8
Ethyl {(5E)-5-[(5-bromo-1H-indol-3-yl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl}acetate
CAS 432017-16-8C16H13BrN2O4S
Methyl 2-[(5E)-5-(1H-indol-3-ylmethylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]acetate chemical structure, C15H12N2O4S, CAS 178881-74-8
Methyl 2-[(5E)-5-(1H-indol-3-ylmethylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]acetate
CAS 178881-74-8C15H12N2O4S
(Z)-5-((1H-Indol-3-yl)methylene)-4-thioxothiazolidin-2-one chemical structure, C12H8N2OS2
(Z)-5-((1H-Indol-3-yl)methylene)-4-thioxothiazolidin-2-one
C12H8N2OS2