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Murcko scaffold

N-(1,1-Dioxo-2,3-dihydrothiophen-3-yl)-N-phenylbenzenesulfonamide scaffold

21 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
21
With full pages
5
Scaffold SMILES

O=S1(=O)C=CC(N(c2ccccc2)S(=O)(=O)c2ccccc2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(1,1-Dioxo-2,3-dihydrothiophen-3-yl)-N-phenylbenzenesulfonamide page
Murcko scaffold O=S1(=O)C=CC(N(c2ccccc2)S(=O)(=O)c2ccccc2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

4-{[(4-Methylphenyl)sulfonyl]phenylamino}-4,5-dihydrothiophene-1,1-dione chemical structure, C17H17NO4S2, CAS 294668-97-6
4-{[(4-Methylphenyl)sulfonyl]phenylamino}-4,5-dihydrothiophene-1,1-dione
CAS 294668-97-6C17H17NO4S2
N-(1,1-Dioxo-2,3-dihydrothiophen-3-yl)-N-(4-methoxyphenyl)-4-methylbenzenesulfonamide chemical structure, C18H19NO5S2, CAS 299955-96-7
N-(1,1-Dioxo-2,3-dihydrothiophen-3-yl)-N-(4-methoxyphenyl)-4-methylbenzenesulfonamide
CAS 299955-96-7C18H19NO5S2
N-(1,1-Dioxo-2,3-dihydrothiophen-3-yl)-N-(4-methoxyphenyl)-4-nitrobenzenesulfonamide chemical structure, C17H16N2O7S2, CAS 433307-76-7
N-(1,1-Dioxo-2,3-dihydrothiophen-3-yl)-N-(4-methoxyphenyl)-4-nitrobenzenesulfonamide
CAS 433307-76-7C17H16N2O7S2
4-Chloro-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-(4-methoxyphenyl)benzenesulfonamide chemical structure, C17H16ClNO5S2, CAS 433321-11-0
4-Chloro-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-(4-methoxyphenyl)benzenesulfonamide
CAS 433321-11-0C17H16ClNO5S2
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-N-(3-methoxyphenyl)benzenesulfonamide chemical structure, C17H17NO5S2, CAS 327067-33-4
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-N-(3-methoxyphenyl)benzenesulfonamide
CAS 327067-33-4C17H17NO5S2
N-(4-Bromophenyl)-N-(1,1-dioxo-2,3-dihydrothiophen-3-yl)-4-methylbenzenesulfonamide chemical structure, C17H16BrNO4S2, CAS 616214-35-8
N-(4-Bromophenyl)-N-(1,1-dioxo-2,3-dihydrothiophen-3-yl)-4-methylbenzenesulfonamide
CAS 616214-35-8C17H16BrNO4S2
N-(1,1-Dioxo-2,3-dihydrothiophen-3-yl)-N-(4-ethoxyphenyl)-4-methylbenzenesulfonamide chemical structure, C19H21NO5S2, CAS 620590-14-9
N-(1,1-Dioxo-2,3-dihydrothiophen-3-yl)-N-(4-ethoxyphenyl)-4-methylbenzenesulfonamide
CAS 620590-14-9C19H21NO5S2
N-(1,1-Dioxido-2,3-dihydro-3-thienyl)-N-(3-methylphenyl)benzenesulfonamide chemical structure, C17H17NO4S2, CAS 327067-27-6
N-(1,1-Dioxido-2,3-dihydro-3-thienyl)-N-(3-methylphenyl)benzenesulfonamide
CAS 327067-27-6C17H17NO4S2
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-N-(4-methoxyphenyl)benzenesulfonamide chemical structure, C17H17NO5S2, CAS 327067-31-2
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-N-(4-methoxyphenyl)benzenesulfonamide
CAS 327067-31-2C17H17NO5S2
4-Chloro-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-(p-tolyl)benzenesulfonamide chemical structure, C17H16ClNO4S2, CAS 630065-49-5
4-Chloro-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-(p-tolyl)benzenesulfonamide
CAS 630065-49-5C17H16ClNO4S2
N-(1,1-Dioxido-2,3-dihydro-3-thienyl)-N-(4-ethylphenyl)benzenesulfonamide chemical structure, C18H19NO4S2, CAS 713506-19-5
N-(1,1-Dioxido-2,3-dihydro-3-thienyl)-N-(4-ethylphenyl)benzenesulfonamide
CAS 713506-19-5C18H19NO4S2
4-Chloro-N-(1,1-dioxo-2,3-dihydrothiophen-3-yl)-N-(4-ethoxyphenyl)benzenesulfonamide chemical structure, C18H18ClNO5S2, CAS 831206-08-7
4-Chloro-N-(1,1-dioxo-2,3-dihydrothiophen-3-yl)-N-(4-ethoxyphenyl)benzenesulfonamide
CAS 831206-08-7C18H18ClNO5S2
4-[(4-Fluorophenyl)(phenylsulfonyl)amino]-4,5-dihydrothiophene-1,1-dione chemical structure, C16H14FNO4S2, CAS 327067-19-6
4-[(4-Fluorophenyl)(phenylsulfonyl)amino]-4,5-dihydrothiophene-1,1-dione
CAS 327067-19-6C16H14FNO4S2
N-(1,1-Dioxido-2,3-dihydro-3-thienyl)-N-(4-ethylphenyl)-4-methylbenzenesulfonamide chemical structure, C19H21NO4S2, CAS 831237-38-8
N-(1,1-Dioxido-2,3-dihydro-3-thienyl)-N-(4-ethylphenyl)-4-methylbenzenesulfonamide
CAS 831237-38-8C19H21NO4S2
4-Chloro-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-(3-methoxyphenyl)benzenesulfonamide chemical structure, C17H16ClNO5S2, CAS 831243-77-7
4-Chloro-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-(3-methoxyphenyl)benzenesulfonamide
CAS 831243-77-7C17H16ClNO5S2
N-(1,1-Dioxo-2,3-dihydrothiophen-3-yl)-N-(3-methoxyphenyl)-4-methylbenzenesulfonamide chemical structure, C18H19NO5S2, CAS 327067-35-6
N-(1,1-Dioxo-2,3-dihydrothiophen-3-yl)-N-(3-methoxyphenyl)-4-methylbenzenesulfonamide
CAS 327067-35-6C18H19NO5S2
N-(1,1-Dioxo-2,3-dihydrothiophen-3-yl)-N-phenylbenzenesulfonamide chemical structure, C16H15NO4S2, CAS 327067-13-0
N-(1,1-Dioxo-2,3-dihydrothiophen-3-yl)-N-phenylbenzenesulfonamide
CAS 327067-13-0C16H15NO4S2
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-4-fluoro-N-(p-tolyl)benzenesulfonamide chemical structure, C17H16FNO4S2, CAS 380189-24-2
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-4-fluoro-N-(p-tolyl)benzenesulfonamide
CAS 380189-24-2C17H16FNO4S2
4-[(4-Methylphenyl)(phenylsulfonyl)amino]-4,5-dihydrothiophene-1,1-dione chemical structure, C17H17NO4S2, CAS 327067-25-4
4-[(4-Methylphenyl)(phenylsulfonyl)amino]-4,5-dihydrothiophene-1,1-dione
CAS 327067-25-4C17H17NO4S2
4-Chloro-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-phenylbenzenesulfonamide chemical structure, C16H14ClNO4S2, CAS 616214-25-6
4-Chloro-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-phenylbenzenesulfonamide
CAS 616214-25-6C16H14ClNO4S2
4-Chloro-N-(4-chlorophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)benzenesulfonamide chemical structure, C16H13Cl2NO4S2, CAS 616214-28-9
4-Chloro-N-(4-chlorophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)benzenesulfonamide
CAS 616214-28-9C16H13Cl2NO4S2