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Murcko scaffold

Ring system with 3 rings and 22 atoms

266 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
266
With full pages
13
Scaffold SMILES

O=C(c1ccccc1)N(c1ccccc1)C1C=CS(=O)(=O)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)N(c1ccccc1)C1C=CS(=O)(=O)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 266 chemicals

4-Chloro-N-(1,1-dioxido-2,3-dihydro-3-thienyl)-N-(4-methylphenyl)benzamide chemical structure, C18H16ClNO3S, CAS 301676-12-0
4-Chloro-N-(1,1-dioxido-2,3-dihydro-3-thienyl)-N-(4-methylphenyl)benzamide
CAS 301676-12-0C18H16ClNO3S
N-(1,1-Dioxido-2,3-dihydro-3-thienyl)-N-(4-methylphenyl)-3,5-dinitrobenzamide chemical structure, C18H15N3O7S, CAS 5548-08-3
N-(1,1-Dioxido-2,3-dihydro-3-thienyl)-N-(4-methylphenyl)-3,5-dinitrobenzamide
CAS 5548-08-3C18H15N3O7S
4-Chloro-N-(1,1-dioxido-2,3-dihydro-3-thienyl)-N-phenylbenzamide chemical structure, C17H14ClNO3S, CAS 303094-04-4
4-Chloro-N-(1,1-dioxido-2,3-dihydro-3-thienyl)-N-phenylbenzamide
CAS 303094-04-4C17H14ClNO3S
N-(1,1-Dioxido-2,3-dihydro-3-thienyl)-2-fluoro-N-(3-methylphenyl)benzamide chemical structure, C18H16FNO3S, CAS 303094-11-3
N-(1,1-Dioxido-2,3-dihydro-3-thienyl)-2-fluoro-N-(3-methylphenyl)benzamide
CAS 303094-11-3C18H16FNO3S
[2,3-Diacetyloxy-5-[(1,1-dioxo-2,3-dihydrothiophen-3-yl)-(4-methylphenyl)carbamoyl]phenyl] acetate chemical structure, C24H23NO9S, CAS 378193-81-8
[2,3-Diacetyloxy-5-[(1,1-dioxo-2,3-dihydrothiophen-3-yl)-(4-methylphenyl)carbamoyl]phenyl] acetate
CAS 378193-81-8C24H23NO9S
4-(tert-Butyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-(p-tolyl)benzamide chemical structure, C22H25NO3S, CAS 540760-26-7
4-(tert-Butyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-(p-tolyl)benzamide
CAS 540760-26-7C22H25NO3S
N-(1,1-Dioxo(3-2,3-dihydrothienyl))-N-(4-ethoxyphenyl)benzamide chemical structure, C19H19NO4S, CAS 713501-10-1
N-(1,1-Dioxo(3-2,3-dihydrothienyl))-N-(4-ethoxyphenyl)benzamide
CAS 713501-10-1C19H19NO4S
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)benzamide chemical structure, C17H14BrNO3S, CAS 831208-11-8
N-(4-Bromophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)benzamide
CAS 831208-11-8C17H14BrNO3S
N-(1,1-Dioxo-2,3-dihydrothiophen-3-yl)-N-(4-ethylphenyl)benzamide chemical structure, C19H19NO3S, CAS 831233-41-1
N-(1,1-Dioxo-2,3-dihydrothiophen-3-yl)-N-(4-ethylphenyl)benzamide
CAS 831233-41-1C19H19NO3S
4-(tert-Butyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-(4-ethoxyphenyl)benzamide chemical structure, C23H27NO4S, CAS 835900-12-4
4-(tert-Butyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-N-(4-ethoxyphenyl)benzamide
CAS 835900-12-4C23H27NO4S
N-(1,1-Dioxo-2,3-dihydrothiophen-3-yl)-4-methyl-N-(4-methylphenyl)benzamide chemical structure, C19H19NO3S, CAS 696637-66-8
N-(1,1-Dioxo-2,3-dihydrothiophen-3-yl)-4-methyl-N-(4-methylphenyl)benzamide
CAS 696637-66-8C19H19NO3S
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-4-ethoxy-N-(p-tolyl)benzamide chemical structure, C20H21NO4S, CAS 852438-34-7
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-4-ethoxy-N-(p-tolyl)benzamide
CAS 852438-34-7C20H21NO4S
N-(1,1-Dioxo-2,3-dihydrothiophen-3-yl)-3-fluoro-N-phenylbenzamide chemical structure, C17H14FNO3S, CAS 838592-14-6
N-(1,1-Dioxo-2,3-dihydrothiophen-3-yl)-3-fluoro-N-phenylbenzamide
CAS 838592-14-6C17H14FNO3S
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-4-methyl-N-(m-tolyl)benzamide chemical structure, C19H19NO3S, CAS 882356-94-7
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-4-methyl-N-(m-tolyl)benzamide
CAS 882356-94-7C19H19NO3S
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-N-(4-ethylphenyl)-4-methoxybenzamide chemical structure, C20H21NO4S, CAS 882355-86-4
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-N-(4-ethylphenyl)-4-methoxybenzamide
CAS 882355-86-4C20H21NO4S
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-3-methyl-N-(m-tolyl)benzamide chemical structure, C19H19NO3S, CAS 882356-86-7
N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-3-methyl-N-(m-tolyl)benzamide
CAS 882356-86-7C19H19NO3S
N-(1,1-Dioxido-2,3-dihydro-3-thienyl)-2-fluoro-N-phenylbenzamide chemical structure, C17H14FNO3S, CAS 303094-10-2
N-(1,1-Dioxido-2,3-dihydro-3-thienyl)-2-fluoro-N-phenylbenzamide
CAS 303094-10-2C17H14FNO3S
N-(1,1-Dioxo-2,3-dihydrothiophen-3-yl)-2-fluoro-N-(4-methoxyphenyl)benzamide chemical structure, C18H16FNO4S, CAS 303992-31-6
N-(1,1-Dioxo-2,3-dihydrothiophen-3-yl)-2-fluoro-N-(4-methoxyphenyl)benzamide
CAS 303992-31-6C18H16FNO4S
4-Chloro-N-(4-chlorophenyl)-N-(1,1-dioxo-2,3-dihydrothiophen-3-yl)benzamide chemical structure, C17H13Cl2NO3S, CAS 303094-05-5
4-Chloro-N-(4-chlorophenyl)-N-(1,1-dioxo-2,3-dihydrothiophen-3-yl)benzamide
CAS 303094-05-5C17H13Cl2NO3S
4-Chloro-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3-nitro-N-(p-tolyl)benzamide chemical structure, C18H15ClN2O5S, CAS 301675-78-5
4-Chloro-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)-3-nitro-N-(p-tolyl)benzamide
CAS 301675-78-5C18H15ClN2O5S
N-(2,4-Dimethoxyphenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)-3-methoxybenzamide chemical structure, C20H21NO6S, CAS 852439-47-5
N-(2,4-Dimethoxyphenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)-3-methoxybenzamide
CAS 852439-47-5C20H21NO6S
N-(2,4-Dimethoxyphenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)-2,3-dimethoxybenzamide chemical structure, C21H23NO7S, CAS 863443-81-6
N-(2,4-Dimethoxyphenyl)-N-(1,1-dioxido-2,3-dihydrothien-3-yl)-2,3-dimethoxybenzamide
CAS 863443-81-6C21H23NO7S
N-(1,1-Dioxido-2,3-dihydro-3-thienyl)-4-fluoro-N-(4-methoxyphenyl)benzamide chemical structure, C18H16FNO4S, CAS 321977-88-2
N-(1,1-Dioxido-2,3-dihydro-3-thienyl)-4-fluoro-N-(4-methoxyphenyl)benzamide
CAS 321977-88-2C18H16FNO4S
4-Chloro-N-(1,1-dioxido-2,3-dihydro-3-thienyl)-N-(4-methoxyphenyl)benzamide chemical structure, C18H16ClNO4S, CAS 303094-06-6
4-Chloro-N-(1,1-dioxido-2,3-dihydro-3-thienyl)-N-(4-methoxyphenyl)benzamide
CAS 303094-06-6C18H16ClNO4S