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Murcko scaffold

Ring system with 2 rings and 11 atoms

20 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 11
Chemicals: 20
With full pages: 3

Scaffold SMILES

O=c1ncsc2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=c1ncsc2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

2-Amino-4H-1,3-benzothiazin-4-one chemical structure, C8H6N2OS, CAS 15601-85-1

2-Amino-4H-1,3-benzothiazin-4-one

CAS 15601-85-1C₈H₆N₂OS

2-Amino-6-nitro-1,3-benzothiazin-4-one chemical structure, C8H5N3O3S, CAS 4501-67-1

2-Amino-6-nitro-1,3-benzothiazin-4-one

CAS 4501-67-1C₈H₅N₃O₃S

2-(4-Oxo-4H-1,3-benzothiazin-2-yl)acetonitrile chemical structure, C10H6N2OS, CAS 67433-02-7

2-(4-Oxo-4H-1,3-benzothiazin-2-yl)acetonitrile

CAS 67433-02-7C₁₀H₆N₂OS

3-(Dimethylamino)-2-(4-oxo-4H-1,3-benzothiazin-2-yl)acrylonitrile chemical structure, C13H11N3OS, CAS 320424-67-7

3-(Dimethylamino)-2-(4-oxo-4H-1,3-benzothiazin-2-yl)acrylonitrile

CAS 320424-67-7C₁₃H₁₁N₃OS

N-(4-Oxo-4H-1,3-benzothiazin-2-yl)guanidine chemical structure, C9H8N4OS, CAS 92432-91-2

N-(4-Oxo-4H-1,3-benzothiazin-2-yl)guanidine

CAS 92432-91-2C₉H₈N₄OS

2-Chloro-benzo[e][1,3]thiazin-4-one chemical structure, C8H4ClNOS, CAS 7742-71-4

2-Chloro-benzo[e][1,3]thiazin-4-one

CAS 7742-71-4C₈H₄ClNOS

Icx-56259537 chemical structure, C10H8N2O2S, CAS 67433-05-0

CAS 67433-05-0C₁₀H₈N₂O₂S

Ethyl (4-oxo-4H-1,3-benzothiazin-2-yl)acetate chemical structure, C12H11NO3S, CAS 67433-03-8

Ethyl (4-oxo-4H-1,3-benzothiazin-2-yl)acetate

CAS 67433-03-8C₁₂H₁₁NO₃S

2-(Methylthio)-4H-benzo[e][1,3]thiazin-4-one chemical structure, C9H7NOS2, CAS 122942-04-5

2-(Methylthio)-4H-benzo[e][1,3]thiazin-4-one

CAS 122942-04-5C₉H₇NOS₂

6-Methyl-4-oxo-4H-1,3-benzothiazine-2-carboxamide chemical structure, C10H8N2O2S, CAS 57446-11-4

6-Methyl-4-oxo-4H-1,3-benzothiazine-2-carboxamide

CAS 57446-11-4C₁₀H₈N₂O₂S

6-Amino-2-(diethylamino)-4H-1,3-benzothiazin-4-one chemical structure, C12H15N3OS, CAS 1170826-84-2

6-Amino-2-(diethylamino)-4H-1,3-benzothiazin-4-one

CAS 1170826-84-2C₁₂H₁₅N₃OS

2-(Methylthio)-8-nitro-6-(trifluoromethyl)-4H-benzo[e][1,3]thiazin-4-one chemical structure, C10H5F3N2O3S2, CAS 1344087-73-5

2-(Methylthio)-8-nitro-6-(trifluoromethyl)-4H-benzo[e][1,3]thiazin-4-one

CAS 1344087-73-5C₁₀H₅F₃N₂O₃S₂

2-(Methylthio)-6,8-bis(trifluoromethyl)-4H-benzo[e][1,3]thiazin-4-one chemical structure, C11H5F6NOS2, CAS 1344087-74-6

2-(Methylthio)-6,8-bis(trifluoromethyl)-4H-benzo[e][1,3]thiazin-4-one

CAS 1344087-74-6C₁₁H₅F₆NOS₂

2-(Methylthio)-6-nitro-4H-benzo[e][1,3]thiazin-4-one chemical structure, C9H6N2O3S2, CAS 1344087-75-7

2-(Methylthio)-6-nitro-4H-benzo[e][1,3]thiazin-4-one

CAS 1344087-75-7C₉H₆N₂O₃S₂

8-Bromo-2-(methylthio)-6-(trifluoromethyl)-4H-benzo[e][1,3]thiazin-4-one chemical structure, C10H5BrF3NOS2, CAS 1344087-76-8

8-Bromo-2-(methylthio)-6-(trifluoromethyl)-4H-benzo[e][1,3]thiazin-4-one

CAS 1344087-76-8C₁₀H₅BrF₃NOS₂

2-Ethoxy-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin-4-one chemical structure, C11H7F3N2O4S, CAS 1104812-34-1

2-Ethoxy-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin-4-one

CAS 1104812-34-1C₁₁H₇F₃N₂O₄S

6-Chloro-2-(methylthio)-8-nitro-4H-benzo[e][1,3]thiazin-4-one chemical structure, C9H5ClN2O3S2, CAS 1377240-43-1

6-Chloro-2-(methylthio)-8-nitro-4H-benzo[e][1,3]thiazin-4-one

CAS 1377240-43-1C₉H₅ClN₂O₃S₂

6-Fluoro-2-(methylthio)-8-nitro-4H-benzo[e][1,3]thiazin-4-one chemical structure, C9H5FN2O3S2, CAS 1383531-43-8

6-Fluoro-2-(methylthio)-8-nitro-4H-benzo[e][1,3]thiazin-4-one

CAS 1383531-43-8C₉H₅FN₂O₃S₂

N-[2-(Diethylamino)-4-oxo-1,3-benzothiazin-6-yl]-2-ethylsulfanylacetamide chemical structure, C16H21N3O2S2, CAS 2243515-43-5

N-[2-(Diethylamino)-4-oxo-1,3-benzothiazin-6-yl]-2-ethylsulfanylacetamide

CAS 2243515-43-5C₁₆H₂₁N₃O₂S₂

2-Chloro-6-(methylsulfonyl)-8-nitro-4H-benzo[e][1,3]thiazin-4-one chemical structure, C9H5ClN2O5S2, CAS 2470059-12-0

2-Chloro-6-(methylsulfonyl)-8-nitro-4H-benzo[e][1,3]thiazin-4-one

CAS 2470059-12-0C₉H₅ClN₂O₅S₂