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Murcko scaffold

4,4'-(1,2-Ethanediyl)bis(2,6-piperazinedione) scaffold

19 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
19
With full pages
9
Scaffold SMILES

O=C1CN(CCN2CC(=O)NC(=O)C2)CC(=O)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4,4'-(1,2-Ethanediyl)bis(2,6-piperazinedione) page
Murcko scaffold O=C1CN(CCN2CC(=O)NC(=O)C2)CC(=O)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

Sobuzoxane chemical structure, C22H34N4O10, CAS 98631-95-9
Sobuzoxane
CAS 98631-95-9C22H34N4O10
Razoxane chemical structure, C11H16N4O4, CAS 21416-67-1
Razoxane
CAS 21416-67-1C11H16N4O4
Dexrazoxane chemical structure, C11H16N4O4, CAS 24584-09-6
Dexrazoxane
CAS 24584-09-6C11H16N4O4
4,4'-(1,2-Ethanediyl)bis(2,6-piperazinedione) chemical structure, C10H14N4O4, CAS 1506-47-4
4,4'-(1,2-Ethanediyl)bis(2,6-piperazinedione)
CAS 1506-47-4C10H14N4O4
Icrf 158 chemical structure, C12H18N4O4, CAS 1155-54-0
Icrf 158
CAS 1155-54-0C12H18N4O4
4,4'-(1,2-Dimethyl-1,2-ethanediyl)bis-2,6-piperazinedione chemical structure, C12H18N4O4, CAS 21416-68-2
4,4'-(1,2-Dimethyl-1,2-ethanediyl)bis-2,6-piperazinedione
CAS 21416-68-2C12H18N4O4
Icrf 193 chemical structure, C12H18N4O4, CAS 21416-88-6
Icrf 193
CAS 21416-88-6C12H18N4O4
1,2-Bis(4-methyl-3,5-dioxopiperazin-1-yl)propane, (R)- chemical structure, C13H20N4O4, CAS 96886-77-0
1,2-Bis(4-methyl-3,5-dioxopiperazin-1-yl)propane, (R)-
CAS 96886-77-0C13H20N4O4
Razoxane, (R)- chemical structure, C11H16N4O4, CAS 24613-06-7
Razoxane, (R)-
CAS 24613-06-7C11H16N4O4
4-[3-(3,5-Dioxopiperazin-1-yl)pentan-2-yl]piperazine-2,6-dione chemical structure, C13H20N4O4, CAS 36753-17-0
4-[3-(3,5-Dioxopiperazin-1-yl)pentan-2-yl]piperazine-2,6-dione
CAS 36753-17-0C13H20N4O4
Zsb11 chemical structure, C16H22N4O8, CAS 98631-87-9
Zsb11
CAS 98631-87-9C16H22N4O8
Carbonic acid, 1,2-ethanediylbis((2,6-dioxo-4,1-piperazinediyl)methylene)dimethyl ester chemical structure, C16H22N4O10, CAS 98632-24-7
Carbonic acid, 1,2-ethanediylbis((2,6-dioxo-4,1-piperazinediyl)methylene)dimethyl ester
CAS 98632-24-7C16H22N4O10
Cardioxane chemical structure, C11H17ClN4O4, CAS 149003-01-0
Cardioxane
CAS 149003-01-0C11H17ClN4O4
Razoxane hydrochloride chemical structure, C11H17ClN4O4, CAS 1383294-26-5
Razoxane hydrochloride
CAS 1383294-26-5C11H17ClN4O4
4,4'-(Ethane-1,2-diyl)bis(1-octylpiperazine-2,6-dione) chemical structure, C26H46N4O4, CAS 2947-87-7
4,4'-(Ethane-1,2-diyl)bis(1-octylpiperazine-2,6-dione)
CAS 2947-87-7C26H46N4O4
4,4'-(Ethane-1,2-diyl)bis(1-tridecylpiperazine-2,6-dione) chemical structure, C36H66N4O4, CAS 66276-89-9
4,4'-(Ethane-1,2-diyl)bis(1-tridecylpiperazine-2,6-dione)
CAS 66276-89-9C36H66N4O4
4,4'-(Ethane-1,2-diyl)bis[1-(propan-2-yl)piperazine-2,6-dione] chemical structure, C16H26N4O4, CAS 61533-53-7
4,4'-(Ethane-1,2-diyl)bis[1-(propan-2-yl)piperazine-2,6-dione]
CAS 61533-53-7C16H26N4O4
4,4'-(Ethane-1,2-diyl)bis(1-propylpiperazine-2,6-dione) chemical structure, C16H26N4O4, CAS 61533-52-6
4,4'-(Ethane-1,2-diyl)bis(1-propylpiperazine-2,6-dione)
CAS 61533-52-6C16H26N4O4
4,4'-(Ethane-1,2-diyl)bis(1-ethylpiperazine-2,6-dione) chemical structure, C14H22N4O4, CAS 61533-51-5
4,4'-(Ethane-1,2-diyl)bis(1-ethylpiperazine-2,6-dione)
CAS 61533-51-5C14H22N4O4