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Murcko scaffold

3-Phenylpiperidin-4-one scaffold

25 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
25
With full pages
4
Scaffold SMILES

O=C1CCNCC1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenylpiperidin-4-one page
Murcko scaffold O=C1CCNCC1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

Ethyl 1-methyl-4-oxo-5-phenyl-piperidine-3-carboxylate chemical structure, C15H19NO3, CAS 7494-89-5
Ethyl 1-methyl-4-oxo-5-phenyl-piperidine-3-carboxylate
CAS 7494-89-5C15H19NO3
3-Phenylpiperidin-4-one hydrochloride chemical structure, C11H14ClNO, CAS 910875-39-7
3-Phenylpiperidin-4-one hydrochloride
CAS 910875-39-7C11H14ClNO
3-Phenylpiperidin-4-one chemical structure, C11H13NO, CAS 76041-09-3
3-Phenylpiperidin-4-one
CAS 76041-09-3C11H13NO
N-[2-Oxo-2-(4-oxo-3-phenylpiperidin-1-yl)ethyl]acetamide chemical structure, C15H18N2O3, CAS 913092-75-8
N-[2-Oxo-2-(4-oxo-3-phenylpiperidin-1-yl)ethyl]acetamide
CAS 913092-75-8C15H18N2O3
1-Methyl-3-phenylpiperidin-4-one chemical structure, C12H15NO, CAS 3881-28-5
1-Methyl-3-phenylpiperidin-4-one
CAS 3881-28-5C12H15NO
3-(2-Fluorophenyl)-1-methylpiperidin-4-one chemical structure, C12H14FNO, CAS 76041-40-2
3-(2-Fluorophenyl)-1-methylpiperidin-4-one
CAS 76041-40-2C12H14FNO
1,1-Dimethyl-4-oxo-3-phenylpiperidin-1-ium bromide chemical structure, C13H18BrNO, CAS 7465-25-0
1,1-Dimethyl-4-oxo-3-phenylpiperidin-1-ium bromide
CAS 7465-25-0C13H18BrNO
tert-Butyl 3-(4-fluorophenyl)-4-oxopiperidine-1-carboxylate chemical structure, C16H20FNO3, CAS 632352-74-0
tert-Butyl 3-(4-fluorophenyl)-4-oxopiperidine-1-carboxylate
CAS 632352-74-0C16H20FNO3
tert-Butyl 4-oxo-3-phenylpiperidine-1-carboxylate chemical structure, C16H21NO3, CAS 632352-56-8
tert-Butyl 4-oxo-3-phenylpiperidine-1-carboxylate
CAS 632352-56-8C16H21NO3
1-Methyl-4-oxo-5-phenyl-piperidine-3-carboxylic acid ethyl ester hydrochloride chemical structure, C15H20ClNO3, CAS 7473-02-1
1-Methyl-4-oxo-5-phenyl-piperidine-3-carboxylic acid ethyl ester hydrochloride
CAS 7473-02-1C15H20ClNO3
Methyl 4-oxo-3-phenylpiperidine-1-carboxylate chemical structure, C13H15NO3, CAS 1263280-83-6
Methyl 4-oxo-3-phenylpiperidine-1-carboxylate
CAS 1263280-83-6C13H15NO3
Ethyl 5-(4-fluorophenyl)-1-methyl-4-oxopiperidine-3-carboxylate chemical structure, C15H18FNO3, CAS 1263870-60-5
Ethyl 5-(4-fluorophenyl)-1-methyl-4-oxopiperidine-3-carboxylate
CAS 1263870-60-5C15H18FNO3
tert-Butyl 3-(4-hydroxy-2-methylphenyl)-4-oxopiperidine-1-carboxylate chemical structure, C17H23NO4, CAS 1247091-09-3
tert-Butyl 3-(4-hydroxy-2-methylphenyl)-4-oxopiperidine-1-carboxylate
CAS 1247091-09-3C17H23NO4
tert-Butyl 3-(4-((tert-butyldimethylsilyl)oxy)-2-methylphenyl)-4-oxopiperidine-1-carboxylate chemical structure, C23H37NO4Si, CAS 1307795-73-8
tert-Butyl 3-(4-((tert-butyldimethylsilyl)oxy)-2-methylphenyl)-4-oxopiperidine-1-carboxylate
CAS 1307795-73-8C23H37NO4Si
4-Oxo-5-phenyl-piperidine-3-carboxylic acid ethyl ester chemical structure, C14H17NO3, CAS 1096168-16-9
4-Oxo-5-phenyl-piperidine-3-carboxylic acid ethyl ester
CAS 1096168-16-9C14H17NO3
tert-Butyl 3-(3,4-dichlorophenyl)-4-oxopiperidine-1-carboxylate chemical structure, C16H19Cl2NO3, CAS 1160260-13-8
tert-Butyl 3-(3,4-dichlorophenyl)-4-oxopiperidine-1-carboxylate
CAS 1160260-13-8C16H19Cl2NO3
tert-Butyl 3-(3-chlorophenyl)-4-oxopiperidine-1-carboxylate chemical structure, C16H20ClNO3, CAS 869720-07-0
tert-Butyl 3-(3-chlorophenyl)-4-oxopiperidine-1-carboxylate
CAS 869720-07-0C16H20ClNO3
1-Boc-3-(3',4'-difluoro-phenyl)-piperidin-4-one chemical structure, C16H19F2NO3, CAS 869720-05-8
1-Boc-3-(3',4'-difluoro-phenyl)-piperidin-4-one
CAS 869720-05-8C16H19F2NO3
tert-Butyl 3-(2-methylphenyl)-4-oxopiperidine-1-carboxylate chemical structure, C17H23NO3, CAS 869720-03-6
tert-Butyl 3-(2-methylphenyl)-4-oxopiperidine-1-carboxylate
CAS 869720-03-6C17H23NO3
3-(2,4-Dichlorophenyl)piperidin-4-one chemical structure, C11H11Cl2NO, CAS 1367938-32-6
3-(2,4-Dichlorophenyl)piperidin-4-one
CAS 1367938-32-6C11H11Cl2NO
3-(2-Chlorophenyl)-4-piperidinone Hydrochloride chemical structure, C11H13Cl2NO, CAS 1425366-60-4
3-(2-Chlorophenyl)-4-piperidinone Hydrochloride
CAS 1425366-60-4C11H13Cl2NO
3-(4-Chlorophenyl)-4-piperidinone Hydrochloride chemical structure, C11H13Cl2NO, CAS 1425366-64-8
3-(4-Chlorophenyl)-4-piperidinone Hydrochloride
CAS 1425366-64-8C11H13Cl2NO
tert-Butyl 3-(4-cyanophenyl)-4-oxopiperidine-1-carboxylate chemical structure, C17H20N2O3, CAS 1425336-90-8
tert-Butyl 3-(4-cyanophenyl)-4-oxopiperidine-1-carboxylate
CAS 1425336-90-8C17H20N2O3
tert-Butyl 3-(3-fluorophenyl)-4-oxopiperidine-1-carboxylate chemical structure, C16H20FNO3, CAS 1425336-70-4
tert-Butyl 3-(3-fluorophenyl)-4-oxopiperidine-1-carboxylate
CAS 1425336-70-4C16H20FNO3