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Murcko scaffold

Ring system with 4 rings and 26 atoms

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
9
With full pages
1
Scaffold SMILES

O=S(=O)(c1ccccc1)N1CCN(c2cccc(N3CCCC3)c2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)N1CCN(c2cccc(N3CCCC3)c2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

1-(4-Chlorophenyl)sulfonyl-4-(4-nitro-3-pyrrolidin-1-ylphenyl)piperazine chemical structure, C20H23ClN4O4S, CAS 347354-93-2
1-(4-Chlorophenyl)sulfonyl-4-(4-nitro-3-pyrrolidin-1-ylphenyl)piperazine
CAS 347354-93-2C20H23ClN4O4S
1-(4-Methylphenyl)sulfonyl-4-(4-nitro-3-pyrrolidin-1-ylphenyl)piperazine chemical structure, C21H26N4O4S, CAS 347354-47-6
1-(4-Methylphenyl)sulfonyl-4-(4-nitro-3-pyrrolidin-1-ylphenyl)piperazine
CAS 347354-47-6C21H26N4O4S
1-(Benzenesulfonyl)-4-(4-nitro-3-pyrrolidin-1-ylphenyl)piperazine chemical structure, C20H24N4O4S, CAS 347354-73-8
1-(Benzenesulfonyl)-4-(4-nitro-3-pyrrolidin-1-ylphenyl)piperazine
CAS 347354-73-8C20H24N4O4S
1-(Benzenesulfonyl)-4-(2-nitro-5-pyrrolidin-1-ylphenyl)piperazine chemical structure, C20H24N4O4S, CAS 431992-94-8
1-(Benzenesulfonyl)-4-(2-nitro-5-pyrrolidin-1-ylphenyl)piperazine
CAS 431992-94-8C20H24N4O4S
1-(3,4-Dichlorophenyl)sulfonyl-4-(4-nitro-3-pyrrolidin-1-ylphenyl)piperazine chemical structure, C20H22Cl2N4O4S, CAS 593237-43-5
1-(3,4-Dichlorophenyl)sulfonyl-4-(4-nitro-3-pyrrolidin-1-ylphenyl)piperazine
CAS 593237-43-5C20H22Cl2N4O4S
N-[4-[4-(4-Nitro-3-pyrrolidin-1-ylphenyl)piperazin-1-yl]sulfonylphenyl]acetamide chemical structure, C22H27N5O5S, CAS 593237-58-2
N-[4-[4-(4-Nitro-3-pyrrolidin-1-ylphenyl)piperazin-1-yl]sulfonylphenyl]acetamide
CAS 593237-58-2C22H27N5O5S
1-(4-Fluorophenyl)sulfonyl-4-(4-nitro-3-pyrrolidin-1-ylphenyl)piperazine chemical structure, C20H23FN4O4S, CAS 662163-68-0
1-(4-Fluorophenyl)sulfonyl-4-(4-nitro-3-pyrrolidin-1-ylphenyl)piperazine
CAS 662163-68-0C20H23FN4O4S
1-(3,4-Dimethylphenyl)sulfonyl-4-(4-nitro-3-pyrrolidin-1-ylphenyl)piperazine chemical structure, C22H28N4O4S, CAS 701970-16-3
1-(3,4-Dimethylphenyl)sulfonyl-4-(4-nitro-3-pyrrolidin-1-ylphenyl)piperazine
CAS 701970-16-3C22H28N4O4S
1-(4-Bromophenyl)sulfonyl-4-(4-nitro-3-pyrrolidin-1-ylphenyl)piperazine chemical structure, C20H23BrN4O4S, CAS 725706-43-4
1-(4-Bromophenyl)sulfonyl-4-(4-nitro-3-pyrrolidin-1-ylphenyl)piperazine
CAS 725706-43-4C20H23BrN4O4S