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Murcko scaffold

Ring system with 3 rings and 18 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
8
With full pages
5
Scaffold SMILES

O=c1[nH]cc(C=C2C=Nc3ccccc32)c(=O)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]cc(C=C2C=Nc3ccccc32)c(=O)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

5-(3-Indolylmethylene)barbituric acid chemical structure, C13H9N3O3, CAS 24774-42-3
5-(3-Indolylmethylene)barbituric acid
CAS 24774-42-3C13H9N3O3
5-[(5-Methoxy-1H-indol-3-yl)methylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione chemical structure, C16H15N3O4, CAS 866038-47-3
5-[(5-Methoxy-1H-indol-3-yl)methylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione
CAS 866038-47-3C16H15N3O4
(5Z)-1-Butyl-5-(1H-indol-3-ylmethylidene)-1,3-diazinane-2,4,6-trione chemical structure, C17H17N3O3, CAS 313953-57-0
(5Z)-1-Butyl-5-(1H-indol-3-ylmethylidene)-1,3-diazinane-2,4,6-trione
CAS 313953-57-0C17H17N3O3
6-Hydroxy-5-[(Z)-(2-methylindol-3-ylidene)methyl]-1-prop-2-enylpyrimidine-2,4-dione chemical structure, C17H15N3O3, CAS 5309-51-3
6-Hydroxy-5-[(Z)-(2-methylindol-3-ylidene)methyl]-1-prop-2-enylpyrimidine-2,4-dione
CAS 5309-51-3C17H15N3O3
5-(1H-Indol-3-ylmethylene)-1,3-dimethyl-pyrimidine-2,4,6-trione chemical structure, C15H13N3O3, CAS 198220-35-8
5-(1H-Indol-3-ylmethylene)-1,3-dimethyl-pyrimidine-2,4,6-trione
CAS 198220-35-8C15H13N3O3
(5Z)-5-(1H-Indol-3-ylmethylidene)-1-(prop-2-en-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione chemical structure, C16H13N3O3, CAS 300839-71-8
(5Z)-5-(1H-Indol-3-ylmethylidene)-1-(prop-2-en-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione
CAS 300839-71-8C16H13N3O3
(5E)-1-tert-Butyl-5-(1H-indol-3-ylmethylidene)-1,3-diazinane-2,4,6-trione chemical structure, C17H17N3O3, CAS 373370-35-5
(5E)-1-tert-Butyl-5-(1H-indol-3-ylmethylidene)-1,3-diazinane-2,4,6-trione
CAS 373370-35-5C17H17N3O3
Methyl 3-[(1,3-dimethyl-2,4,6-trioxo-1,3-diazinan-5-ylidene)methyl]-1H-indole-2-carboxylate chemical structure, C17H15N3O5, CAS 346450-27-9
Methyl 3-[(1,3-dimethyl-2,4,6-trioxo-1,3-diazinan-5-ylidene)methyl]-1H-indole-2-carboxylate
CAS 346450-27-9C17H15N3O5